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Health care utilisation among older people with Down syndrome compared to specific medical guidelines for health surveillance : a Swedish national register study

Background: Specific medical guidelines for health surveillance exist for people with Down syndrome (DS) since 25 years but knowledge of adherence to the guidelines is lacking. The guidelines were developed to avoid unnecessary suffering from preventable conditions. The aims of the study were to investigate 1) planned health care visits in relation to the co-morbidities described in specific medic

Clinical studies of extended-half-life recombinant FVIII products for prophylaxis in adults and children : A critical review from the physician's perspective

This review compares the methodology of published clinical studies investigating the extended-half-life (EHL) factor VIII (FVIII) products, rFVIIIFc (efmoroctocog alfa, Elocta®/Eloctate®), BAY 94-9027 (damoctocog alfa pegol, Jivi®), BAX 855 (rurioctocog alfa pegol, Adynovate®) and N8-GP (turoctocog alfa pegol, Esperoct®) including the phase 2/3 studies, A-LONG (NCT01181128), PROTECT VIII (NCT01580

Alveolar mast cells shift to an FcεRI-expressing phenotype in mild atopic asthma: a novel feature in allergic asthma pathology.

Background: A unique feature of alveolar mast cells is their low high-affinity IgE receptor (FcεRI) expression. Recent discoveries in uncontrolled asthma suggest that the appearance of FcεRI-expressing alveolar mast cells may be a novel disease-specific feature of allergic asthma. This study investigates whether increased FcεRI-expressing alveolar mast cells are present in patients with mild aller

Terminstider-lasaret-2023-24

Terminstider läsåret 2023/24 Beslut Sida 1 av 3 Student och utbildning Diarienummer U 2022/287 2022-06-20 Reviderad: 2022-12-01 Terminstider läsåret 2023/24 För läsåret 2023/24 gäller följande terminstider: Höstterminen 2023 pågår från och med måndagen den 28 augusti 2023 till och med söndagen den 14 januari 2024. Vårterminen 2024 pågår från och med måndagen 15 januari 2024 till och med söndagen d

https://www.medarbetarwebben.lu.se/sites/medarbetarwebben.lu.se/files/2022-12/Terminstider-lasaret-2023-24.pdf - 2026-05-14

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Master’s Dissertation Structural Mechanics JIMMY PERSSON Report TV SM -5181 JIM M Y PERSSO N N U M ER IC A L A N A LY SIS O F C O M PR ESSIO N PER PEN D IC U LA R TO TH E G R A IN IN G LU LA M B EA M S W ITH A N D W ITH O U T R EIN FO R C EM EN T NUMERICAL ANALYSIS OF COMPRESSION PERPENDICULAR TO THE GRAIN IN GLULAM BEAMS WITH AND WITHOUT REINFORCEMENT Detta är en tom sida! Copyright © 2011 by Str

https://www.byggmek.lth.se/fileadmin/byggnadsmekanik/publications/tvsm5000/web5181.pdf - 2026-05-14

IgG glycan hydrolysis by a bacterial enzyme as a therapy against autoimmune conditions.

EndoS from Streptococcus pyogenes efficiently hydrolyzes the functionally important and conserved N-linked glycan of IgG in human blood. Repeated i.v. administration of EndoS in rabbits completely hydrolyzes the glycans of the whole IgG pool, despite the generation of anti-EndoS antibodies. EndoS administration had no apparent effects on the health of the animals. EndoS hydrolysis of the IgG glyca

Induction of platelet thrombi by bacteria and antibodies.

We have characterized 2 distinct mechanisms through which infectious agents may promote platelet adhesion and thrombus formation in flowing blood, thus contributing to the progression of disease. In one case, the process initiates when the integrin alpha(IIb)beta(3) mediates platelet arrest onto immobilized bacterial constituents that have bound plasma fibrinogen. If blood contains antibodies agai

Group B Streptococcus suppression of phagocyte functions by protein-mediated engagement of human Siglec-5

Group B Streptococcus (GBS) is a leading cause of invasive bacterial infections in human newborns. A key GBS virulence factor is its capsular polysaccharide (CPS), displaying terminal sialic acid (Sia) residues which block deposition and activation of complement on the bacterial surface. We recently demonstrated that GBS Sia can bind human CD33-related Sia-recognizing immunoglobulin (Ig) superfami

Prevention and Management of Bleeding Episodes in Children with Hemophilia

Regular prophylactic treatment with factor VIII (FVIII) and factor IX (FIX) concentrates in hemophilia A and B, respectively, is introduced in early infancy and has resulted in dramatic improvement of the conditions. Recombinant FVIII and FIX concentrates have been available for > 25 years and have been modified and refined through the years; however, unfortunately frequent intravenous administrat

Countercurrent distribution of lymphocytes from human peripheral blood in an aqueous two-phase system. : II. Separation into subsets of lymphocytes with distinctive functions

Lymphocytes from human peripheral blood were separated by Countercurrent distribution (CCD) in a charged aqueous two-phase system composed of Dextran T 500 and polyethylene glycol 6000. Maximal responses to the T-cell mitogens phytohemagglutinin and concanavalin A were detected in a part of the distribution corresponding to the area where the highest percentage of E rosetting cells were seen. Anti

Engineering Af1521 improves ADP-ribose binding and identification of ADP-ribosylated proteins

Protein ADP-ribosylation is a reversible post-translational modification that regulates important cellular functions. The identification of modified proteins has proven challenging and has mainly been achieved via enrichment methodologies. Random mutagenesis was used here to develop an engineered Af1521 ADP-ribose binding macro domain protein with 1000-fold increased affinity towards ADP-ribose. T

Terminstider 2019 2020

2018-06-07 Dnr U 2018/357 Postadress Box 117, 221 00 LUND Hämtställe 13 Besöksadress Sölvegatan 29 B Telefon dir 046-222 70 58, växel 046-222 00 00; Telefax 046-222 04 95 E-post Daniel.Huledal@stu.lu.se S tudent och utb i ldn ing Danie l Huleda l Till fakulteter och särskilda verksamheter med grundutbildning Terminstider läsåren 2019/20 och 2020/21 Universitetet tog 2009-10-22 beslut om principer

https://www.graduateschool.sam.lu.se/sites/graduateschool.sam.lu.se/files/terminstider_2019_2020.pdf - 2026-05-14

Studies on hereditary C2 deficiency: Frequent occurrence of severe infections, atherosclerosis and rheumatological manifestations

Popular Abstract in Swedish Komplementsystemet utgör en del av den medfödda immuniteten och är viktigt i försvaret mot angripande mikroorganismer. Ärftlig C2-brist (C2D) är en av de vanligaste bristerna inom komplementsystemet och förekommer i en frekvens av 1: 20 000 hos personer med västerländsk härstamning. I de aktuella undersökningarna har mer än 40 personer med C2D identifierats och observerThe complement system is a part of the innate immunity and is essential in the defence against microorganisms. Hereditary C2 deficiency (C2D) is one of the most common complement deficiency states with an estimated prevalence of 1:20,000 in persons of Western descent. In the present investigation, the identification of more than 40 C2D persons at a single centre combined with long observation peri

NordIAS Call-for-applications 2026 0

NordIAS Visiting Fellowship Programme, Call for Applications 2026 NordIAS Visiting Fellowship Programme _____________ Call for Applications – 2026 Deadline 13 January 2026 The Nordic Institutes for Advanced Studies have formed the network NordIAS with the aim of increasing collaborations among the institutes and affiliated fellows and staff. The NordIAS visiting fellowship programme is intended to

https://www.pi.lu.se/en/sites/pi.lu.se.en/files/2025-11/NordIAS_Call-for-applications_2026_0.pdf - 2026-05-14