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An early anonymous Greek translation of the Qur'ān : The fragments from Niketas Byzantios' Refutatio and the anonymous Abjuratio

Abstract in SpanishPresentamos en este artículo los fragmentos de la primera traducción completa conocida del Corán, acompañados de una introducción y notas. Esta traducción al griego, realizada algún tiempo antes de 780 d.C., no ha sido hasta ahora reconocida en los estudios coránicos ni en los bizantinos, sin que sus principales rasgos hayan sido advertidos. En el artículo argumentamos que la trIn this article the fragments of the first known complete translation of the Qur’ān are presented with introduction and notes. This translation into Greek, produced sometime before 870 CE, has not previously been recognized in Qur’ānic or Byzantine studies, and its main traits have not been noted. In the article it is argued that the translation attempts to render the Qur’ānic text closely and in

Current Practices, Experiences, and Views in Clinical Hypnosis : Findings of an International Survey

An online survey of 691 clinicians who use hypnosis was conducted in 31 countries to gain a broad real-world picture of current practices, views, and experiences in clinical hypnosis. Among 36 common clinical uses, stress reduction, wellbeing and self-esteem-enhancement, surgery preparations, anxiety interventions, mindfulness facilitation, and labor and childbirth applications were the most frequ

Feasibility and safety of synchrotron-based X-ray phase contrast imaging as a technique complementary to histopathology analysis

X-ray phase contrast imaging (X-PCI) is a powerful technique for high-resolution, three-dimensional imaging of soft tissue samples in a non-destructive manner. In this technical report, we assess the quality of standard histopathological techniques performed on formalin-fixed, paraffin-embedded (FFPE) human tissue samples that have been irradiated with different doses of X-rays in the context of a

Cellulose Acetate Microbeads for Controlled Delivery of Essential Micronutrients

The controlled delivery of micronutrients to soil and plants is essential to increase agricultural yields. However, this is today achieved using fossil fuel-derived plastic carriers, posing environmental risks and contributing to global carbon emissions. In this work, a novel and efficient way to prepare biodegradable zinc-impregnated cellulose acetate beads for use as controlled release fertilize

Overexpression of the key metabolic protein CPT1A defines mantle cell lymphoma patients with poor response to standard high dose chemotherapy independent of MIPI and complement established high-risk factors

The variable outcome to standard immunochemotherapy for mantle cell lymphoma (MCL) patients is a clinical challenge. Established risk factors, including high MCL international prognostic index (MIPI), high proliferation (Ki-67), non-classic (blastoid/pleomorphic) morphology, and mutated TP53, only partly identify patients in need of alternative treatment. Deepened understanding of biological facto

Changes to consultations and diagnosis of osteoarthritis in primary care during the COVID-19 pandemic

OBJECTIVE: General practitioners (GP) are often the first medical professionals to treat musculoskeletal complaints. Yet the impact of COVID-19 on primary care utilisation for musculoskeletal complaints is largely unknown. This study quantifies the impact of the pandemic on primary care utilisation for musculoskeletal complaints and specifically osteoarthritis (OA) in the Netherlands.DESIGN: We ex

Coulomb excitation of Rn 222

The nature of quadrupole and octupole collectivity in Rn222 was investigated by determining the electric-quadrupole (E2) and octupole (E3) matrix elements using subbarrier, multistep Coulomb excitation. The radioactive Rn222 beam, accelerated to 4.23 MeV/u, was provided by the HIE-ISOLDE facility at CERN. Data were collected in the Miniball γ-ray spectrometer following the bombardment of two targe

Characterization of Male-Produced Aggregation Pheromone of the Bean Flower Thrips Megalurothrips sjostedti (Thysanoptera: Thripidae)

Aggregation of the bean flower thrips, Megalurothrips sjostedti (Trybom) (Thysanoptera: Thripidae), has been observed on cowpea, Vigna unguiculata (L.) Walp. To understand the mechanism underpinning this behavior, we studiedthe responses of M. sjostedti to headspace volatiles from conspecifics in a four-arm olfactometer. Both male andfemale M. sjostedti were attracted to male, but not to female od

Appendiceal tumours and pseudomyxoma peritonei : Literature review with PSOGI/EURACAN clinical practice guidelines for diagnosis and treatment

Pseudomyxoma Peritonei (PMP) is a rare peritoneal malignancy, most commonly originating from a perforated epithelial tumour of the appendix. Given its rarity, randomized controlled trials on treatment strategies are lacking, nor likely to be performed in the foreseeable future. However, many questions regarding the management of appendiceal tumours, especially when accompanied by PMP, remain unans

An evaluation of the industrial symbiosis systems modeling

Industrial symbiosis, a concept derived from industrial ecology, emphasizes the collaborative and synergic production among industries. The particular focus is on cyclical flows of resources (material, energy, water, and/or by-products), in order to minimize impacts on the environment. In this way, an industry could reuse the discarded resources of another industry as an input to production. Essen

Clinical notes as prognostic markers of mortality associated with diabetes mellitus following critical care : A retrospective cohort analysis using machine learning and unstructured big data

BACKGROUND: Clinical notes are ubiquitous resources offering potential value in optimizing critical care via data mining technologies.OBJECTIVE: To determine the predictive value of clinical notes as prognostic markers of 1-year all-cause mortality among people with diabetes following critical care.MATERIALS AND METHODS: Mortality of diabetes patients were predicted using three cohorts of clinical

Collaborative Future-Making: Bridging the Everyday and the Global Political Economy of Automated Health

Health services and medical research are subject to growing use of ADM. Whilst such technology brings many benefits, it is important to understand that it is not just a tool but involves a more fundamental shift in the infrastructure through which healthcare takes place. Where that development is driven by the private sector, it also indicates a wider paradigmatic change in how healthcare is provi

Quantification and Profiling of Early and Late Differentiation Stage T Cells in Mantle Cell Lymphoma Reveals Immunotherapeutic Targets in Subsets of Patients

With the aim to advance the understanding of immune regulation in MCL and to identify targetable T-cell subsets, we set out to combine image analysis and spatial omic technology focused on both early and late differentiation stages of T cells. MCL patient tissue (n = 102) was explored using image analysis and GeoMx spatial omics profiling of 69 proteins and 1812 mRNAs. Tumor cells, T helper (TH) c

IsiXhosa Intellectual Traditions Digital Archive: Digitizing isiXhosa texts from 1870-1914

This article offers an overview of the IsiXhosa Intellectual Traditions Digital Archive, which hosts digitized texts and images of early isiXhosa newspapers and books from 1870-1914. The archive offers new opportunities for a range of research across multiple fields, and responds to debates around the importance of African intellectual traditions and their indigenous language sources in generating

WT1-mediated repression of the proapoptotic transcription factor ZNF224 is triggered by the BCR-ABL oncogene.

The Kruppel-like protein ZNF224 is a co-factor of the Wilms' tumor 1 protein, WT1. We have previously shown that ZNF224 exerts a specific proapoptotic role in chronic myelogenous leukemia (CML) K562 cells and contributes to cytosine arabinoside-induced apoptosis, by modulating WT1-dependent transcription of apoptotic genes. Here we demonstrate that ZNF224 gene expression is down-regulated both in

EVOLUTION OF A beta 42 AND A beta 40 LEVELS AND A beta 42/A beta 40 RATIO IN PLASMA DURING PROGRESSION OF ALZHEIMER'S DISEASE: A MULTICENTER ASSESSMENT

Objective: To better understand the seemingly contradictory plasma beta-amyloid (A beta) results in Alzheimer's disease (AD) patients by using a newly developed plasma A beta assay, the INNO-BIA plasma A beta forms, in a multicenter study. Methods: A combined retrospective analysis of plasma A beta isoforms on mild cognitive impairment (MCI) from three large cross-sectional studies involving 643 s