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The Simplest Multi-key Linearly Homomorphic Signature Scheme

We consider the problem of outsourcing computation on data authenticated by different users. Our aim is to describe and implement the simplest possible solution to provide data integrity in cloud-based scenarios. Concretely, our multi-key linearly homomorphic signature scheme (MKLHS) allows users to upload signed data on a server, and at any later point in time any third party can query the server

Event-related potentials to visual processing of incongruities in negated and affirmative sentences

In spite of the fact that negation has been the focus of many studies, the way it is processed in human communication still eludes us. Previous studies of negation using event-related potentials (ERPs) have reported inconclusive results as to whether or not negation poses difficulties for processing. While some have found that negation is initially ignored and incongruities in negated sentences do

Biochar production and application in small-scale farming in Kenya : Yield increases and local perceptions

Degradation of agricultural soils and forest resources are two pervasive challenges in rural landscapes of sub-Saharan Africa. Biochar-producing biomass gasification technologies attract evermore interest because these can empower small-scale farmers to produce energy and food more sustainably byimproving energy use efficiencies, lowering emissions and strengthening climate resilience. In order to

Modeling Multi-Fraction Coastal Aeolian Sediment Transport With Horizontal and Vertical Grain-Size Variability

Grain size affects the rates of aeolian sediment transport on beaches. Sediment in coastal environments typically consists of multiple grain-size fractions and exhibits spatiotemporal variations. Still, conceptual and numerical aeolian transport models are simplified and often only include a single fraction that is constant over the model domain. It is unclear to what extent this simplification is

GPR55 signalling promotes proliferation of pancreatic cancer cells and tumour growth in mice, and its inhibition increases effects of gemcitabine

The life expectancy for pancreatic cancer patients has seen no substantial changes in the last 40 years as very few and mostly just palliative treatments are available. As the five years survival rate remains around 5%, the identification of novel pharmacological targets and development of new therapeutic strategies are urgently needed. Here we demonstrate that inhibition of the G protein-coupled

Quantification of Phagocytosis Using Flow Cytometry

Phagocytosis is relevant for many research fields and is often measured as a functional outcome. However, accurate quantification can be challenging, and many researchers find it difficult to study in a robust manner. There are many ways to measure phagocytosis, but what is often overlooked is the importance of experimental design and how the analysis is planned and performed. Experimental factors

GCNPMDA : Human microbe-disease association prediction by hierarchical graph convolutional network with layer attention

Microorganisms play a crucial role in various physiological processes, including metabolism, immune defense, nutrition absorption, defense against cancer, and protection against pathogen colonization. Changes in microbial communities serve as potential biomarkers for diseases, offering significant insights into disease treatment and diagnosis. However, the association between microorganisms and di

Microplastics in commercial bivalves and their association with farm structures : A case study in a relevant aquaculture area of Brazil

This study investigated the presence of MPs in three species of bivalves cultivated in Brazil: Crassostrea gigas, Perna perna, and Nodipecten nodosus. Our hypothesis was that the different structures and plastic materials used in the cultivation of these bivalves could serve as a contributing source of MPs. Our results showed the presence of MPs in all species, with C. gigas showing the highest le

Survey among experts on the future role of tau-PET in clinical practice and trials

BACKGROUND: Recent advancements in Alzheimer's disease (AD) biomarker research and clinical trials prompt reflection on the value and consequently appropriate use of tau positron emission tomography (tau-PET) in the future. METHODS: We conducted an online survey among dementia and PET experts worldwide to investigate the anticipated future role of tau-PET in clinical practice and trials. RESULTS:

Computational modeling of peritoneal dialysis : An overview

Peritoneal dialysis (PD) is a kidney replacement therapy for patients with end-stage renal disease. It is becoming more popular as a result of a rising interest in home dialysis. Its effectiveness depends on several physiological and technical factors, which have led to the development of various computational models to better understand and predict PD outcomes. In this review, we traced the evolu

Skin, scales, and cells in a Jurassic plesiosaur

Plesiosaurs are an iconic group of Mesozoic marine reptiles with an evolutionary history spanning over 140 million years (Ma).1 Their skeletal remains have been discovered worldwide; however, accompanying fossilized soft tissues are exceptionally rare.2 Here, we report a virtually complete plesiosaur from the Lower Jurassic (∼183 Ma)3 Posidonia Shale of Germany that preserves skin traces from arou

Shortening antibiotic therapy duration for hospital-acquired bloodstream infections in critically ill patients : a causal inference model from the international EUROBACT-2 database

INTRODUCTION: Hospital-acquired bloodstream infections (HA-BSIs) are severe and require antibiotic therapy. In non-complicated BSIs, shortened therapy reduces side effects without compromising efficacy. The impact of shortened antibiotic therapy in HA-BSI critically ill patients without indication of prolonged therapy requires further evaluation. METHODS: Using the international prospective EUROBA

Testing the Activity of Complement Convertases in Serum/Plasma for Diagnosis of C4NeF-Mediated C3 Glomerulonephritis

Autoantibodies termed C3-nephritic factor (C3NeF), which stabilize convertases of the alternative complement pathway, often stimulate autoinflammatory diseases. However, knowledge about analogous autoantibodies acting on the classical pathway (C4NeF) is limited to a few reports, which indicate association with kidney dysfunction, systemic lupus erythematous, and infections. C4NeF may appear indepe

Design of Oversampled Uniform DFT Filter Banks with Delay Specifications using Quadratic Optimization

Subband adaptive filters have been proposed to avoid the drawbacks of slow convergence and high computational complexity associated with time domain adaptive filters. Subband processing introduces transmission delays caused by the filter bank and signal degradations due to aliasing effects. One efficient way to reduce the aliasing effects is to allow a higher sample rate than critically needed in

The association of mobility disability, weight status and job strain : A cross-sectional study

Aims: The study investigated whether people with mobility disability (MD) and/or obesity had higher job strain than people without it, and whether social support at work modifies this association. Methods: The study included 35,160 individuals (25-64 years of age) from the Stockholm Public Health Surveys of 2006 and 2010. Data on MD and obesity (BMI ≥ 3/4 30 kg/m2 calculated from weight (kg) and h

Robotic Friction Stir Welding—Seam-Tracking Control, Force Control and Process Supervision

Purpose – This study aims to enable robotic friction stir welding (FSW) in practice. The use of robots has hitherto been limited, because of the large contact forces necessary for FSW. These forces are detrimental for the position accuracy of the robot. In this context, it is not sufficient to rely on the robot’s internal sensors for positioning. This paper describes and evaluates a new method for