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Plant cells carry Ca2+ ATPases to maintain the low resting level of cytosolic Ca2+ (0.1-0.2 µM) found in all eukaryotes. Plant Ca2+ ATPases are mainly located in the plasma membrane, the endoplasmic reticulum and in the vacuolar membrane, and consequently large Ca2+ gradients are created across these membranes. The Ca2+ gradients are used by the cell to transmit information in a variety of physiol
A method based on the coupled decay-chain equations for extracting the isotopic and the isomeric composition of a postaccelerated radioactive ion beam is presented and demonstrated on a data set from a Coulomb excitation experiment. This is the first attempt of analyzing the content of a postaccelerated radioactive ion beam using this technique. The beam composition is required for an absolute nor
I artikeln görs en översikt över jordbrukets och skogsbrukets närvaro i konsten i Sverige under 1900-talet. Den innehåller också analyser och diskussioner rörande hur, när och varför det agrara motivet är närvarande alternativt frånvarande i konsten under perioden.
A major concern for contemporary organizations is how to gain support of business processes from standardized software package such as enterprise resource planning (ERP) systems. To gain support adoption of such standardized information and communication technologies (ICTs) demands that either the system is adjusted to existing business processes or that business processes are adjusted to the syst
Background Rheumatoid arthritis (RA) and osteoarthritis (OA) are important musculoskeletal diseases that the EUMUSC.NET project developed Standards of Care (SOC) for. Objective The purpose was to explore factors to enable successful implementation of the SOC for RA and OA. Methods A combined set of methods was used; a literature search, a European survey among patients, clinicians and policymakers
Previous studies showed that larvae of Methona themisto (Hubner, [ 1818]) (Lepidoptera: Nymphalidae) display a showy yellow color to avoid predation. In addition, these larvae absorb secondary compounds when feeding on Brunfelsia uniflora (Pohl) D. Don (Solanaceae) plants, although this does not prevent pupal parasitism by Palmistichus elaeisis Delvare & LaSalle, 1993 (Hymenoptera: Eulophidae)
I denna uppsats undersöks aborträtten i Sverige och Irland samt innebörden av artiklarna 2, 3, 8, 9 och 10 i Europakonventionen i förhållande till aborter. Syftet är att belysa övergripande likheter och skillnader mellan de svenska och de irländska reglerna och att diskutera hur de nationella reglerna kan förändras, för att stärka olika rättigheter och bättre harmoniera med Europakonventionen. DetThis essay investigates abortion law in Sweden and Ireland and the meaning of articles 2, 3, 8, 9 and 10 of the European Convention on Human Rights, in relation to abortions. The aim is to illustrate general similarities and differences between Swedish and Irish abortion law and to discuss how the law might be changed in order to strengthen different rights and to increase its harmonisation with t
Upplevelserummet blir alltmer viktigare. Tidigare undersökningar om upplevelserummet har enbart fokuserats på de fysiska faktorerna. Men vad som även behöver undersökas är vilka faktorer utöver de fysiska som kan påverka en människas uppfattning om upplevelserummet och beteendet. Vårt syfte är att undersöka vilka faktorer som främst påverkar samt hur dessa påverkar kundens kvalitetsuppfattning av
Denna uppsats behandlar fattigdomsbekämpning utifrån svensk biståndspolitik. Bi-ståndsgivning har länge varit en självklar del i både internationell och svensk politik, ändå har inga större framgångar skett med att utrota fattigdom. Syftet med uppsatsen är att utvärdera Sveriges politik om bistånd genom det senast utgivna dokumentet om bi-ståndspolitik – Biståndspolitisk plattform – utgiven av regThis essay concern poverty alleviation through Swedish aid policy. Giving aid has been an evident part of both international and Swedish policy for a long time, yet there has been no great success with eradicating poverty. The purpose is to evaluate Sweden’s aid policy through its most recently published document on aid policy, which the govern-ment published in March 2014. The document will be an
Leonard Talmy’s influential binary motion event typology has encountered four main challenges: (a) additional language types; (b) extensive “type-internal” variation; (c) the role of other relevant form classes than verbs and “satellites;” and (d) alternative definitions of key semantic concepts like Motion, Path and Manner. After reviewing these issues, we show that the theory of Holistic Spatial
In 2015, the World health organisation (WHO) released a press statement together with the International Agency for Research in Cancer (IARC) classifying processed meat as carcinogenic. Since then, research in this area has been focused on finding the underlying mechanism(s) responsible for the link between processed meat and the increased prevalence of colorectal cancer. One of the main hypotheses
MOTIVATION: Transcription factors (TFs) are key regulators of gene expression, and can activate or repress multiple target genes, forming regulatory units, or regulons. Understanding downstream effects of these regulators includes evaluating how TFs cooperate or compete within regulatory networks. Here we present RTNduals, an R/Bioconductor package that implements a general method for analyzing pa
Genetically determined myoclonus disorders are a result of a large number of genes. They have wide clinical variation and no systematic nomenclature. With next-generation sequencing, genetic diagnostics require stringent criteria to associate genes and phenotype. To improve (future) classification and recognition of genetically determined movement disorders, the Movement Disorder Society Task Forc
Filamentous fungi play a key role as decomposers in Earth’s nutrient cycles. In soils, substrates are heterogeneously distributed in microenvironments. Hence, individual hyphae of a mycelium may experience very different environmental conditions simultaneously. In the current work, we investigated how fungi cope with local environmental variations at single-cell level. We developed a method based
Hurler syndrome (HS) is a lysosomal storage disease characterized by multisystem morbidity and death in early childhood. Hematopoietic stem cell transplantation (HSCT) results in long-term survival, although with significant residual disease burden. How this residual disease affects the health-related quality of life is unknown. Therefore, we conducted a multicenter cohort study on functional and
In this review we explore the similarities between spinocerebellar ataxias and dystonias, and suggest potentially shared molecular pathways using a gene co-expression network approach. The spinocerebellar ataxias are a group of neurodegenerative disorders characterized by coordination problems caused mainly by atrophy of the cerebellum. The dystonias are another group of neurological movement diso
Background: Rare and ultra-rare diseases (URDs) are often chronic and life-threatening conditions that have a profound impact on sufferers and their families, but many are notoriously difficult to detect. Niemann-Pick disease type C (NP-C) serves to illustrate the challenges, benefits and pitfalls associated with screening for ultra-rare inborn errors of metabolism (IEMs). A comprehensive, non-sys
Background: The clinical demarcation of the syndrome progressive myoclonus ataxia is unclear, leading to a lack of recognition and difficult differentiation from other neurological syndromes. Objectives: The objective of this study was to apply a refined definition of progressive myoclonus ataxia and describe the clinical characteristics in patients with progressive myoclonus ataxia and with isola
