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Preoperative chemotherapy for colon cancer and short-term outcomes—a nationwide cohort study
Skiljeförfarande inom arbetsrätten och dess förenlighet med arbetsrättens skyddsvärden
Skiljeförfarande är ett vanligt förekommande rättsligt institut inom kommersi-ella sammanhang och framhålls ofta som ett effektivt och diskret alternativ till prövning i allmän domstol. När skiljeklausuler införs i anställningsavtal aktua-liseras emellertid särskilda problem, eftersom förfarandet kan innebära bety-dande nackdelar för arbetstagaren, bland annat i form av höga kostnader, be-gränsadeArbitration is a common legal institution in commercial contexts and is fre-quently described as an efficient and discreet alternative to proceedings in a general court. When arbitration clauses are included in employment contracts, specific problems arise, as the procedure can entail significant disadvantages for the employee, including high costs, limited opportunities for review and a lack of t
Den allmänna principen om reklamation - Ett minne blott? - Den allmänna reklamationsskyldigheten i ljuset av NJA 2025 s. 374
Denna uppsats utreder huruvida rättsläget för den allmänna principen om att reklamera vid avtalsbrott utanför det lagreglerade området har förändrats till följd av Högsta domstolens avgörande i NJA 2025 s. 374 ”Brf Ida”. För att klargöra vad reklamation är konstateras att preskription har en förutbestämd tidsram, medan reklamationsfristens start- och slutpunkt varierar bero-ende på de enskilda omsThis thesis examines whether the legal situation for the general principle regarding the duty to give notice of breach of contract outside the scope of legislation has shifted due to the Supreme Court’s decision in NJA 2025 s. 374 “Brf Ida”. To clarify what the general principle of a duty to give notice is, it is noted that prescription has a fixed starting point. By contrast, the duty to give not
Brottsprovokation och straffansvar - En studie av betänkandet till Lag (2027:000) om särskilda provokativa åtgärder
Provokation saknar idag uttrycklig lagreglering i svensk rätt och har under lång tid varit föremål för rättslig diskussion. Med provokation, agent provo-ceateur, avses utredningsåtgärder genom vilka myndigheter aktivt förmår eller påverkar en person att handla på ett visst sätt, vilket kan leda till att brottslig verksamhet avslöjas men samtidigt innebär en risk för att brott framkallas. Utvecklin
Standardized mortality ratio in adults with congenital heart disease
Aims The prevalence of adults with congenital heart disease (ACHD) is rising due to improved paediatric care. In parallel, updated data on prognosis in adult life are needed. Objectives The aim was to calculate the standardized mortality ratio (SMR) and death rates in ACHD compared to the general population. Methods and results Data were obtained from the national register of congenital heart dise
Prothrombin concentrations in middle-aged men and women – stability over time and correlations with cardiovascular risk factors
Background Prothrombin is a vitamin K-dependent glycoprotein synthesized in the liver and circulating in blood as an inactive zymogen. The corresponding activated thrombin enzyme is a central player in hemostasis and thrombosis. Still, little is known about the individual variation over time of the prothrombin concentration in plasma in the general population. Objectives This study aimed to establ
Organisatoriska och strategiska beslut om AI i B2B-marknadsföring
Artificial intelligence (AI) is frequently described as a strategic resource for marketing, yet empirical insights into how AI is adopted and used in business-to-business (B2B) marketing remain limited. Prior research has predominantly focused on technological capabilities or consumer-oriented contexts, while organizational and strategic considerations in B2B firms have received less attention. Th
Computed tomography urography in macroscopic hematuria : a retrospective study with implications for standard care pathway
Accounting for the Scarcity of Time as Patients Approach End of Life: The Construction of End-Weighted Time Toxicity
ObjectivesPeople with serious illness approaching end of life often end up in emergency and hospital care, frequently against expressed preferences. Consequently, oncology trials record care days as a measure of treatment burden called “time toxicity.” However, this measure ignores the diminishing marginal utility of time: that the value of a day is higher when fewer remain. We aimed to incorporat
The impact of alcohol use disorder and PTSD comorbidity on risk of suicide attempt
Mercury stocks and methylmercury production remain unaffected by 17 years of experimental permafrost thaw
Mercury (Hg) has been stored in permafrost peatlands for millennia. As permafrost thaw is predicted to increase with ongoing climate warming, Hg is at risk to be remobilized from those peatlands and hotspots for Hg methylation could potentially form. Monomethylmercury (MeHg) is a known neurotoxin and a health concern to northern communities if Hg is remobilized, transformed to MeHg and subsequentl
Positive effects of a perioperative training intervention in Ivor Lewis oesophageal surgery : a randomised, controlled multicentre trial
Background: The effects of peri-operative training interventions in connection with oesophageal surgery have not been thoroughly investigated. The aim of this randomised, controlled, single-blind study was to evaluate a peri-operative physical training programme in patients undergoing oesophageal cancer resection surgery due to cancer of the oesophagus or the gastro-oesophageal junction. Methods:
Risk of substance-related problems in hypochondriasis
Individual Plant Species' Occurrences and Habitat Preferences Are Related to Variation in Community-Level Reflectance in Grasslands
Questions: Earth observation is an important tool in biological monitoring. Previous studies have shown that variation in grassland canopy reflectance can explain gradients in plant community composition. However, there is a need for methods that allow the interpretation of the overall spectral signal of complex grassland vegetation in terms of existing knowledge about individual species' habitat
Tumor-Infiltrating Immune Cells Are More Abundant in Lung Metastases From Colorectal Cancer Than in Paired Primary Tumors and Their Prognostic Value Depends on Adjuvant Chemotherapy
INTRODUCTION: The immune microenvironment plays a crucial role in the progression of colorectal cancer (CRC), but its variation across primary tumors and metastatic sites remains incompletely understood. In this study, we compared the composition and prognostic significance of the immune microenvironment in lung metastases, paired primary tumors, and liver metastases from a retrospective cohort of
Beta-cell-specific C3 deficiency exacerbates metabolic dysregulation and insulin resistance in obesity
Background: C3 is highly expressed in human and rodent pancreatic islets, which secrete insulin to regulate blood glucose homeostasis. We have previously shown that cytosolic C3 protects pancreatic beta-cells from stress, by allowing cytoprotective autophagy, and that the same intracellular pool of C3 also protects beta-cells from cytokine-induced apoptosis. Methods: We now generated a beta-cell s
Evaluation of a Novel Automated Cerebral Ventricular Drainage System for Intracranial Pressure Monitoring and Cerebrospinal Fluid Drainage in Neurocritical Care Patients : A Prospective, Randomized Clinical Study
BACKGROUND: Neurointensive care is moving toward more automated patient management. This study aimed to evaluate a novel external ventricular drainage (EVD) system, the VGuard® system, as a tool for intracranial pressure (ICP) monitoring and automating ventricular drainage of cerebrospinal fluid (CSF), focusing on its safety and potential to reduce complications associated with manual EVD manageme
Genetic Susceptibility to Diabetes Subtypes and Risk of Developing Coronary Artery Disease
OBJECTIVE: Diabetes significantly increases the risk for atherosclerotic complications, including coronary artery disease (CAD). Previous studies have suggested that adult-onset diabetes can be classified into five different clinical subtypes, including moderate obesity-related diabetes (MOD). The aim of this study was to investigate the genetic associations between the five diabetes subtypes and
The overlooked role of internalizing symptoms in adolescent executive function: Insights from self- and teacher ratings
This study examined how self- and teacher-rated executive functioning (EF), measured with the Behavior Rating Inventory of Executive Function – Second Edition, differed between adolescents with and without self-reported neurodevelopmental disorders (NDDs; e.g., autism), across levels of internalizing symptoms, and how EF, NDDs, and internalizing symptoms related to academic achievement. Analyses i
