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Utbildningsstyrelsen har i samarbete med undervisnings- och kulturministeriet börjat utveckla rektorsutbildningarna mera målmedvetet än tidigare, i synnerhet de utbildningsprogram för läroanstalternas ledning som finansieras via programmet Kunnig (Osaava). En åtgärd som ansetts vara nödvändig som underlag för utvecklingsarbetet har varit att kartlägga olika länders praxis för utbildning av läroansThe Finnish National Board of Education, in collaboration with the Ministry of Education and Culture, has started to develop the training of rectors in a more systematic way by utilizing the funds which were allocated for the Osaava programme. One of the pre-liminary measures in this regard included a survey concerning the continuing education practices of school leaders on a worldwide basis. The

Microbe-mediated mn oxidation—a proposed model of mineral formation

Manganese oxides occur in a wide range of environmental settings either as coatings on rocks, sediment, and soil particles, or as discrete grains. Although the production of biologically mediated Mn oxides is well established, relatively little is known about microbial-specific strategies for utilizing Mn in the environment and how these affect the morphology, structure, and chemistry of associate

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Our aim was to assess the incidence of symptomatic ulnar nerve dislocation and its influence on surgical outcome after primary and revision surgeries in ulnar nerve entrapment at the elbow (ulnar neuropathy at the elbow (UNE) or cubital tunnel syndrome). The influence of pre- or intra-operative ulnar nerve dislocation on postoperative outcome was assessed in 548 surgically treated cases (548 nerve

Comparable Initial Engagement of Intracellular Signaling Pathways by Parathyroid Hormone Receptor Ligands Teriparatide, Abaloparatide, and Long-Acting PTH

Multiple analogs of parathyroid hormone, all of which bind to the PTH/PTHrP receptor PTH1R, are used for patients with osteoporosis and hypoparathyroidism. Although ligands such as abaloparatide, teriparatide (hPTH 1-34 [TPTD]), and long-acting PTH (LA-PTH) show distinct biologic effects with respect to skeletal and mineral metabolism endpoints, the mechanistic basis for these clinically-important

Plasma S1P (Sphingosine-1-Phosphate) Links to Hypertension and Biomarkers of Inflammation and Cardiovascular Disease : Findings From a Translational Investigation

S1P (Sphingosine-1-phosphate) is an important regulator of immune cell trafficking and vascular dysfunction contributing to the development and progression of overt hypertension. Although targeting S1P signaling revealed therapeutic potential in different experimental hypertension studies, validations of S1P-blood pressure (BP) associations in humans are lacking. In a translational approach, we ex

Machine learning compared with rule-in/rule-out algorithms and logistic regression to predict acute myocardial infarction based on troponin T concentrations

ObjectiveComputerized decision‐support tools may improve diagnosis of acute myocardial infarction (AMI) among patients presenting with chest pain at the emergency department (ED). The primary aim was to assess the predictive accuracy of machine learning algorithms based on paired high‐sensitivity cardiac troponin T (hs‐cTnT) concentrations with varying sampling times, age, and sex in order to rule

Low diagnostic yield of ST elevation myocardial infarction amplitude criteria in chest pain patients at the emergency department

To evaluate the diagnostic yield of the ECG criteria for ST-elevation myocardial infarction in a large cohort of emergency department chest pain patients, and to determine whether extended ECG criteria or reciprocal ST depression can improve accuracy. Design: Observational, register-based diagnostic study on the accuracy of ECG criteria for ST-elevation myocardial infarction. Between Jan 2010 and

Glass-bottled drinking water : a time capsule to study the historic presence of hazardous chemicals using effect-based methods

Background: Contamination of drinking water by hazardous chemicals can be associated with human health risks. Recent studies using effect-based in vitro methods have demonstrated that a large part of the observed toxic effects are caused by unknown chemicals. In this study, we have used a panel of effect-based methods to study the presence of chemical contaminants in a unique material; glass-bottl

Factors Associated With the Decline of C-Peptide in a Cohort of Young Children Diagnosed With Type 1 Diabetes

CONTEXT: Understanding factors involved in the rate of C-peptide decline is needed to tailor therapies for type 1 diabetes (T1D). OBJECTIVE: Evaluate factors associated with rate of C-peptide decline after a T1D diagnosis in young children. DESIGN: Observational study. SETTING: Academic centers. PARTICIPANTS: A total of 57 participants from the Environmental Determinants of Diabetes in the Young (

Bladder and upper urinary tract cancers as first and second primary cancers

Background: Previous population-based studies on second primary cancers (SPCs) in urothelial cancers have focused on known risk factors in bladder cancer patients without data on other urothelial sites of the renal pelvis or ureter. Aims: To estimate sex-specific risks for any SPCs after urothelial cancers, and in reverse order, for urothelial cancers as SPCs after any cancer. Such two-way analysi

Geochemical fingerprints of ginkgoales across the triassic-jurassic boundary of greenland

Premise of research. Geochemical fingerprinting of fossil plants is a relatively new research field complementing morphological analyses and providing information for paleoenvironmental interpretations. Ginkgoales contains a single extant species but was diverse through the Mesozoic and is an excellent target for biochemical analyses. Methodology. Cuticles derived from fresh and fallen autumn leav

The Shrunken pore syndrome is associated with poor prognosis and lower quality of life in heart failure patients : the HARVEST-Malmö study

AIMS: This study aimed to investigate the association between the 'Shrunken pore syndrome' (SPS) and risk of death, 30 day rehospitalization, and health-related quality of life (QoL) in heart failure (HF) patients. SPS is characterized by a difference in renal filtration between cystatin C and creatinine, resulting in a low eGFRcystatin C /eGFRcreatinine ratio.METHODS AND RESULTS: A total of 373 p

Extreme altitude changes between night and day during marathon flights of great snipes

Summary Several factors affect the flight altitude of migratory birds, such as topography, ambient temperature, wind conditions, air humidity, predation avoidance, landmark orientation, and avoiding over-heating from direct sunlight.1, 2, 3, 4, 5, 6 Recent tracking of migratory birds over long distances has shown that migrants change flight altitude more commonly and dramatically than previously t

Flexibility and Control of Circadian Activity, Migratory Restlessness and Fueling in Two Songbird Migrants

Juvenile songbirds rely on an endogenous program, encoding direction, distance, fueling, and timing of migration. Migratory distance is species-specific, expressed as a period of migratory restlessness, for which the length is correlated with distance, while fueling is modified to meet anticipated flight distances controlled by geomagnetic cues and amount of day-light available for foraging. How d

Customer expectations of unattended grocery delivery services: mapping forms and determinants

PurposeIn the rapidly growing e-grocery segment, unattended delivery is an emerging practice with the potential to offer a superior delivery experience. The purpose of this study is to contribute to the body of knowledge for unattended grocery delivery services by empirically identifying and describing the forms and determinants of customer expectations.Design/methodology/approachA multiple case s