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OBJECTIVE: To examine the endometrial expression pattern of messenger RNA (mRNA) for selected matrix metalloproteinases (MMP) and tissue inhibitor of metalloproteinases-1 (TIMP-1). DESIGN: Experimental study. SETTING: Department of Obstetrics and gynecology of the Palacky University Medical School and University Hospital, Olomouc, Czech Republic, Department of Obsterics and Gynecology, University

To assess the stability of polyomavirus antibodies in serial samples over time and the incidence and age-specific prevalence of polyomavirus infections, we established enzyme immunoassays (EIAs) using purified yeast-expressed virus-like particles (VLPs) containing the VP1 major capsid proteins of JC virus (JCV) and the AS and SB strains of BK virus (BKV). A random subsample of 150 Finnish women wh

Endogenous and exogenous sex hormones are of pivotal importance for women’s health. Hormone therapy has been widely studied but there is limited data about androgen and androgen replacement therapy. The aim of this study was to delineate the possible interrelations between endogenous androgens and women’s particularly pertaining to cardiovascular disease (CVD) and risk markers for CVD in perimeno

Allt sedan 1989 har vi i den södra sjukvårdsregionen gett en 20-poängskurs i grundläggande forskningsmetodik. Vår målsättning har varit att ge många läkare en basal vetenskaplig skolning till glädje för den vardagsnära kvalitetsutvecklingen och verksamhetsuppföljningen, men också att stimulera enstaka läkare till att påbörja en regelrätt forskarutbildning. Vi har genom åren presenterat utvecklingeAt the Department of Community Medicine at Lund University we have given courses in basic research methodology since 1989. The course has yielded 20 points of university credit, the equivalent of one full-time semester of studies, and it has been run part-time, covering one and a half years. Our aim has been to provide a large number of physicians with basic training in research methods, and to st

Aim: Carbon monoxide (CO) in blood as assessed by the COHb% is a marker of the cardiovascular ( CV) risk in smokers. Non-smokers exposed to tobacco smoke similarly inhale and absorb CO. The objective in this population-based cohort study has been to describe inter-individual differences in COHb% in never smokers and to estimate the associated cardiovascular risk. Methods: Of the 8,333 men, aged 34

Wind speed and direction have a significant effect on a flying bird's ground speed. Migrants are therefore expected to be sensitive to wind conditions and this should have consequences for optimal strategies of stopover and refuelling. Based on an earlier model of time-minimizing migration which includes wind condition, we investigate the consequences of the temporal correlation of wind conditions

Control beliefs, i.e. a person's perceived control over his or her own behaviour, are important predictors of psychological functioning in old age. The aim of this study is to examine the mediating effect of housing-related control beliefs on the relationship between housing accessibility and independence in activities of daily living (ADL). Moreover, cross-national differences in five European co

Treatment with alendronate ( Fosamax (R)) has been shown to significantly reduce the risk of fragility fractures. Cost-effectiveness of treatment was assessed in nine European countries in a Markov model and was generally found to be cost effective in women with a previous spine fracture. Introduction Treatment with alendronate (Fosamax (R)) reduces the risk of osteoporotic fractures at the spine,

Web breaks in the dryer section of a paper machine cause loss of production and quality problems. After a web break, the steam pressure in the cylinders must be reduced to avoid overheating. The goal of this project is to determine optimal steam pressure trajectories during web breaks, so that the production is restarted with the same drying properties of the cylinder as before the break. A detail

The aim of this paper is to present and discuss nurses' and physicians' comments in a questionnaire relating to patients' transition from curative treatment to palliative care. The four-page questionnaire relating to experiences of and attitudes towards communication, decision-making, documentation and responsibility of nurses and physicians and towards the competence of patients was developed and