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Protein adducts in plasma as biomarkers of exposure to and risk of organic acid anhydrides

Organic acid anhydrides (OAAs) are important industrial chemicals but also potent inducers of airways diseases. Many exposed workers develop specific IgE and IgG antibodies. Hexahydrophthalic anhydride (HHPA) and methylhexahydrophthalic anhydride (MHHPA) are two particularly sensitising OAAs. The aim of this thesis was to develop and evaluate a method for biological monitoring of exposure to and r

Tools for protective lung ventilation. The elastic pressure-volume curve and aspiration of dead space

Ventilator-induced lung injury (VILI) may contribute to morbidity and mortality of acute lung injury (ALI). Lung protective ventilation (LPV), that reduces VILI, may involve low tidal volume (Vt). Particularly low Vt is possible if dead space ventilation is reduced e.g. by aspiration of dead space gas (ASPIDS). ASPIDS implies that gas rich in CO2 during expiration is aspirated through a separate c

Fertile grounds? : Collective strategies and the political ecology of soil management in Uganda

Proceeding from land degradation and soil fertility decline in sub-Saharan African smallholder agriculture and drawing on empirical research with smallholder farmers in Tororo district in south-eastern Uganda (2010-2012), this thesis identifies local collective strategies in response to changing livelihood conditions. In an attempt to co-produce knowledge with a transformative potential, the thesi

Den utsträckta TV:n - Ett exempel ur praktiken

The aim of this licentiate thesis is twofold: 1) to describe old people’s interest in and prospects of using the television for something other than traditional TV viewing, and 2) to describe the nonlinearities in the design process in which this research was performed. A concept called The Extended TV was developed and tested (by old people, their relatives and care workers) in a new nursing home

On Reduction of Production Disturbances in Manufacturing Systems Based on Discrete-Event Simulation

Improved efficiency in manufacturing systems to achieve increased output and thus reduced production disturbances is a vital area. DES (Discrete-Event Simulation) can visualize and study the dynamic issues related to total efficiency in manufacturing systems. A methodology for production disturbance reduction is presented. Increased performance of manufacturing systems means not only enhanced valu

Efficient Optimization Techniques for Localization and Registration of Images

This thesis focuses on two problems in the field of computer vision and image analysis. The first part of the thesis deals with image localization. The goal is simply to answer the question: Where was this picture taken? To answer this two things are needed: A model of the world, or at least the relevant parts of the world, and a method for relating a new image to the model. The thesis presents ne

Model development for estimating carbon dioxide exchange in Nordic forests and peatlands with MODIS time series data

The ongoing increase in atmospheric greenhouse gas concentrations causes an increase in the global mean air temperature. One important moderator of the atmospheric carbon dioxide (CO2) concentration is the gas exchange between the atmosphere and the biosphere; photosynthesis extracts and respiration releases CO2, resulting in a net exchange. A variety of methods are used to improve our understandi

ENDOTHELIAL- EPITHELIAL INTERACTIONS Blood vessels friends or foes?

Diabetes affects enormous amounts of patients. In type 1 diabetes the insulin producing β cells in the islet of Langerhans are destroyed by the immune system. The β cells, which are located in the pancreas, regulate blood glucose levels. The lack of insulin production requires administration of insulin. This is accomplished by insulin injections. Even though the treatment methods have been improve

A microscopic investigation of miR-34c and miR-205 in Prostate Cancer

The complex genetics of cancer allows tumors to grow and spread undeterred by the control mechanisms of the cell. The importance of protein-coding genes in tumorigenesis is well established. Recently, microRNAs (miRNAs) have emerge as key regulator of development and cellular processes such as differentiation, cell growth and cell death; processes closely linked to cancer. The aim of this thesis w

Effect of experimental complex III deficiency on respiratory chain assembly and function

The assembly of respiratory chain complexes in the mitochondrial inner membrane requires specific factors. Once assembled to form a mature functional complex, complex III (CIII) is a dimer consisting of two monomers, each with eleven subunits. To date, seven assembly factors for CIII are known, of which BCS1L incorporates the Rieske iron-sulfur protein (RISP) in the last stage of the assembly. The

Reading John Climacus: Rhetorical Argumentation, Literary Convention and the Tradition of Monastic Formation

This thesis offers an investigation of the literary form and the literary composition of The Ladder by John Climacus, as well as a study of how the author uses the tradition to form his reader. Besides a brief introduction with a survey of the previous research, the study comprises four chapters. In the first chapter it is shown, from a number of detailed text analyses, that the material in the s

Hemicelluloses from Agricultural and Forestry Crops Isolation, Characterisation, and Enzymatic Hydrolysis

Hemicelluloses are tremendous sources of renewable raw materials, which utilisation have the potential to be highly increased in the future. Hemicelluloses are among the major groups of compounds in plant cell walls, together with cellulose and lignin. These three components are closely associated, making them difficult to separate from each other. Hemicelluloses are complex polysaccharides and tw

Mikrokosmos Förvaltare och Skapelsens Integritet, Den Teologiska Antropologin i Kyrkornas Världsråds JPIC-process med särskild hänsyn till skapelsens integritet

The aim of this dissertation is to discuss the two theologic anthropological concepts microcosm and steward within the World Council of Churches project called the JPIC-process - their JPIC stands for justice, peace and the integrity of creation - and to relate the two anthropological concepts to each other using a theological correlation method. After an introduction the JPIC-process, which offic

Simulation and execution of autonomous robot systems

Traditional off-line programming is not enough in order to use the full potential of virtual models and simulation system in industrial robot applications. The interface between off-line programming system and the robot controller is today restricted to program transfer. In this way a large amount of information is lost since typical robot programming languages is rather limited. If the virtual m

“No Friends but the Mountains” Understanding Population Mobility and Land Dynamics in Iraqi Kurdistan

The link between population mobility and environmental change is fundamental for our understanding of how future global environmental changes will affect our societies, and also how the increased mobility will change our role in the Earth system. Climate change has been predicted as a major cause of human migration, both voluntary and forced, through for example increased storm and drought frequen

Ambivalent Friendship : Anglican Conflict Handling and Education for Peace in Jerusalem 1920-1948

This thesis concerns a religious actor in the civil society in times of violent conflict. During the British Mandate period in Palestine, Jewish, Muslim and Christian children studied together at Anglican missionary schools. At this time Jerusalem bore all the imprints of ethnic and religious separation and division. The Anglican educational project became part of the efforts made by the Anglican

Visually guided swimming in box jellyfish: A study of swimming behaviour in response to visual stimuli

Most animals use eyes to guide their behaviour. Analysing, and understanding, visually guided behaviours gets more complicated the more advanced the animal gets. Box jellyfish provide a relatively simple system for understanding visually guided behaviours. They have a limited nervous system, but they also possess a visual system that is quite impressive for a jellyfish. Box jellyfish have 24 eyes

Chemical communication in mating shore crabs Carcinus maenas

Locating and evaluating a suitable partner for mating is one of the most important events in any sexually reproducing organism. To achieve this, an animal must be able to locate its partner over both long and short distances, and finally evoke the proper mating behaviour. This is made possible by use of conspecific signals picked up by one or several sensory systems, the most well investigated bei

On LFSR based Stream Ciphers - analysis and design

Stream ciphers are cryptographic primitives used to ensure privacy in digital communication. In this thesis we focus on stream ciphers built using Linear Feedback Shift Registers (LFSRs). Several different stream ciphers are analysed and new attacks are presented. In addition, two new stream ciphers are presented, both based on the same design. The first attack is performed on SOBER-t16 and SOBER