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The development of a miniaturised silicon wafer integrated enzyme reactor is described. The reactor was micromachined by anisotropic wet etching of (110) silicon. The enzyme glucose oxidase (GOx) was coupled to the reactor surface with standard methods of immobilising enzyme to silica. The glucose turn-over rate was monitored following a colourimetric assay. The advantage, in terms of high surface
Abstract: This thesis consists of four papers related to various aspects of water waves with vorticity. Paper I: Symmetry of steady periodic gravity water waves with vorticity. We prove that steady periodic two-dimensional rotational gravity water waves with a monotone surface profile between troughs and crests have to be symmetric about the crest, irrespective of the vorticity distribution wit
The aim of this work was to develop, implement and evaluate an independent system with which to calculate the absorbed dose, delivered by high-energy X-ray beams, to the prescription point and the depth of dose maximum. The introduction of such a system in the clinical routine may help ensure high-quality treatment and avoidance of errors which may jeopardise the clinical outcome of the treatment
The formation of the kingdom of Denmark is generally presented as a linear process linking ancient chiefs to the modern nation state of Denmark. This dissertation focuses on the small stories behind this great narrative of Denmark. The purpose is to show that there never was any formation process. Instead, encounters between people in the local landscapes and the Danish kingdom were both considera
Re-occurring hyperglycaemic episodes promote subclinical low-grade inflammation and CVD in type 2 diabetes, emphasising the therapeutic role of tight blood glucose regulation. A tight blood glucose regulation is probably beneficial also in healthy subjects and mild elevations in postprandial glycaemia and triglycerides are associated with impaired flow-mediated dilation and increased markers of ox
Most animals use eyes to guide their behaviour. Analysing, and understanding, visually guided behaviours gets more complicated the more advanced the animal gets. Box jellyfish provide a relatively simple system for understanding visually guided behaviours. They have a limited nervous system, but they also possess a visual system that is quite impressive for a jellyfish. Box jellyfish have 24 eyes
Locating and evaluating a suitable partner for mating is one of the most important events in any sexually reproducing organism. To achieve this, an animal must be able to locate its partner over both long and short distances, and finally evoke the proper mating behaviour. This is made possible by use of conspecific signals picked up by one or several sensory systems, the most well investigated bei
The number of fractures is increasing worldwide, and fractures frequently cause long-term disability, impaired quality of life and sometimes death. The Malmö Preventive Project, a population-based, prospective study, consisting of 22 444 men, mean age 44 and 10 902 women, mean age 50 years, provides data for evaluation of common public health conditions, such as fracture and diabetes. The follow-u
Several studies have reported that bone marrow (BM)-derived stem cells have the capacity to give rise to cells of different type of tissue; an ability termed stem cell plasticity or transdifferentiation. Controversies exist as to how frequent this phenomenon is, or if it may be explained by alternative mechanisms. Here we have used different mouse models to study the potential plasticity of BM-der
The so-called Chilean economic miracle during the 1980s and 1990s connotes not only high-speed economic growth but also a profound structural transformation of the Chilean economy. Most previous research ascribes growth and transformation to the liberalisation of markets and other neo-liberal policy instruments introduced after 1974. Policies, before as well as after 1974, have indeed been importa
This thesis is based on five papers (A-E), all treating various applications of Rice's formula. The areas of application are oceanographic and environmental problems. The first three papers treat properties of encountering waves, that is, waves that a ship encounters while sailing on the ocean. Paper A addresses the problem of computing the intensity of such waves and, in particular, the intensit
This dissertation consists of a primary and a secondary study. The aim of the primary study is to follow-up a group of juveniles diagnosed with conduct disorder (n=351) into adulthood. The secondary study's aim is to question, clarify and attach the questionnaire SOC-29 to the salutogenic theory.In the dissertation different outcomes and outcome measurements are fomulated and discussed. Two perspe
The assessment of ischemic heart disease (IHD) often focuses on the detection of dysfunctional but viable myocardium which may improve in function following revascularization. Dysfunctional but viable myocardium is identified by distinct characteristics with regards to function, perfusion and viability. Therefore, in Paper I we developed a method for quantitative polar representation of left ventr
The vantage point for this thesis is the passport as it was understood and used in the European Union from 1999 to 2001, as a requirement to cross the external borders of the EU and as a symbol of a united Europe free from a spectacular nationalism of the member states. According to nationalism, every nation should have its own state, and every state should be legitimized by a nation. If the mode
Contracts traded on international financial and commodity markets are associated with complex risk structures. In this dissertation we are concerned with two specific types of risks; market risks and credit risks. The first chapter investigates market risks in the context of the Nordic electricity market. The paper performs in- and out-of-sample backtesting of a VaR model based on GARCH volatili
This thesis is based on studies of the clinical use of induced hypothermia as an intervention to reduce mortality and neurological impairment after cardiac arrest. After the publication of two trials indicating benefit of induced hypothermia, we developed a registry to assess outcome, possible adverse events and conduct of induced hypothermia when this intervention was implemented in a clinical p
The test free-electron laser (test-FEL) at MAX-lab in Lund demonstrated for the first time circularly polarized coherent femtosecond pulses at 66 nm wavelength. A 375 MeV electron bunch was seeded by a femtosecond laser at 263 nm and coherent harmonics were extracted in an APPLE-II type elliptical undulator. A thermionic gun with a barium oxide cathode was adapted for photocathode operation, and t
Diabetes affects enormous amounts of patients. In type 1 diabetes the insulin producing β cells in the islet of Langerhans are destroyed by the immune system. The β cells, which are located in the pancreas, regulate blood glucose levels. The lack of insulin production requires administration of insulin. This is accomplished by insulin injections. Even though the treatment methods have been improve
