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Reservoir Pressure Integral Is Independently Associated With the Reduction in Renal Function in Older Adults

Background: Arterial hemodynamic parameters derived from reservoir-excess pressure analysis exhibit prognostic utility. Reservoir-excess pressure analysis may provide useful information about an influence of altered hemodynamics on target organ such as the kidneys. We determined whether the parameters derived from the reservoir-excess pressure analysis were associated with the reduction in estimat

Halving food-related greenhouse gas emissions can be achieved by redistributing meat consumption : Progressive optimization results of the NutriNet-Santé cohort

BACKGROUND: Diet-related greenhouse gas emissions (GHGe) mainly comes from animal-sourced foods. As progressive changes are more acceptable for a sustainable food transition, we aimed to identify nutritionally adequate and culturally acceptable optimized diets ensuring a gradual reduction in GHGe, using observed diet from a large sample of French adults, while considering the mode of food producti

Incidence, Predictors, and Success of Ventricular Tachycardia Catheter Ablation in Arrhythmogenic Right Ventricular Cardiomyopathy (from the Nordic ARVC Registry)

Catheter ablation may reduce ventricular tachycardia (VT) burden in arrhythmogenic right ventricular cardiomyopathy (ARVC) patients. However, little is known about factors predicting need for ablation. Therefore, we sought to investigate predictors and use of VT ablation and to evaluate the postprocedural outcome in ARVC patients. We studied 435 patients from the Nordic ARVC registry including 220

Picoliter sample preparation in MALDI-TOF MS using a micromachined silicon flow-through dispenser

This paper presents a picoliter sample preparation technique utilizing the flow-through principle, allowing on-line coupling of chromatographic systems to be made. The work was performed in order to investigate the characteristics and the physicochemical properties of the sample preparation using typical mobile phase conditions from μ-CLC (column liquid chromatography) separations. The device pres

Lund Concept for De-airing of the Left Heart. Clinical Evaluation.

Background: Residual air accumulated air in the pulmonary veins constitutes a challenge to achievment of complete de-airing in open left heart surgery. To adress this problem, a conceptual method for de-airing was developed in Lund comprising bilateral opening of the pleurae to induce pulmonary collapse and a strategy with gradual pulmonary reperfusion and ventilation at weaning from cardiopulmona

Group-based Parental Support in Child Health Service. Development and evaluation of a group leadership course for nurses.

The close relationship between young children’s living conditions and their healthlater in life is well documented and a safe and healthy environment during earlychildhood promotes cognitive functions and social development during the wholelifespan. Becoming a parent is a major life transition and it is sometimes described as a stressful and vulnerable time involving changes to lifestyle and routi

Is the use of sunscreens a risk factor for malignant melanoma?

The relation between use of sunscreens, different host factors and malignant melanoma was investigated in a population-based, matched case-control study of malignant melanoma in the South Swedish Health Care Region, which has the highest risk for melanoma in Sweden, between 1 July 1988 and 30 June 1990. In total, 400 melanoma patients and 640 healthy controls aged 15-75 years answered a comprehens

Comparative risk of suicide by specific substance use disorders : A national cohort study

Substance use disorders (SUDs) are important risk factors for suicide, yet little is known about how suicide risks vary by specific SUDs. We examined these risks for the first time in a large general population to facilitate comparisons across SUDs. A national cohort study was conducted of all 6,947,191 adults in Sweden. SUDs (opioid, sedative/hypnotic, hallucinogen, cannabis, amphetamine, cocaine

The Gaia reference frame for bright sources examined using VLBI observations of radio stars

Context. Positions and proper motions of Gaia sources are expressed in a reference frame that ideally should be non-rotating relative to distant extragalactic objects, coincident with the International Celestial Reference System (ICRS), and consistent across all magnitudes. For sources fainter than 16th magnitude, this is achieved through Gaia's direct observations of quasars. At brighter magnitud

Gaia Data Release 3 : G RVSphotometry from the RVS spectra

Context.Gaia Data Release 3 (DR3) contains the first release of magnitudes estimated from the integration of Radial Velocity Spectrometer (RVS) spectra for a sample of about 32.2 million stars brighter than GRVS∼ 14 mag (or G ∼ 15 mag). Aims. In this paper, we describe the data used and the approach adopted to derive and validate the GRVS magnitudes published in DR3. We also provide estimates of t

Between Growth and Sustainability : Exploring the Construction of Sustainable Mobility in Swedish Transport Policy

Samtidigt som bilen är själva grunden för det sätt vi förflyttar oss i samhället, utgör bilismen den främsta orsaken till transportsektorns negativa miljö- och hälsoeffekter. Denna avhandling handlar om politiska försök att gå bortom bilen, mot en mer hållbar form av mobilitet. Hållbar mobilitet eller hållbara transporter, som är den mer använda termen i Sverige, har de senaste decennierna kommit Transport policies in Western Europe are increasingly framed in terms of sustainable mobility. This is a response to an urgent need to tackle adverse consequences of the transport system and implies changes in discourses related to transport. Exploring sustainable mobility is a fruitful way of studying discursive development in a policy field historically connected to priorities radically differen

Adapting for shared use – evaluating the lifecycle carbon impact

Vast amounts of resources extracted through the times are in today’s built environment, with only an estimated 20-30% of building material recycled or reused and the sector accounting for over 35% of the EU’s total waste generation. Buildings are also responsible for 25-40% of all global carbon dioxide emissions. Circular Economy (CE) refers to the better management of resources and waste by closi

The bilayer melting transition in lung surfactant bilayers: the role of cholesterol.

Aqueous di persions of a porcine lung surfactant (PLS) extract with and without cholesterol supplementation were analyzed by X-ray scattering. Lamellar liquid-crystalline and gel-type bilayer phases are formed, as in pure phosphatidylcholine (PC)-cholesterol systems. This PLS extract, developed for clinical applications, has a cholesterol content of less than 1% (w/w). Above the limit of swelling,

Early ventilatory management and lung function in the immature newly born. Experimental studies in lambs.

Popular Abstract in Swedish När ett barn föds före graviditetsvecka 30 är andningsinsufficiens eller på engelska kallad respiratory distress syndrome (RDS) ett av de stora kliniska problemen som barnläkaren står inför. Redan på 1920-talet förstod man att det måste finnas ett ytspänningsnedsättande ämne i lungorna och på 1950-talet fann man att för tidigt födda (prematura) barn med RDS hade brist pUsing an animal model, the thesis explores how the initial ventilation of the lungs, and surfactant therapy, should best be managed after premature birth. Material and measurements: The studies were made in newborn lambs delivered by cesarean section. Spread of exogenous surfactant was analysed by mixing it with technetium-labelled macroaggregated human serum albumin and imaging the radioactivity

RoSiB - a 4 pi silicon ball for charged-particle detection in EUROBALL

A 4 pi silicon bail for detection and identification of light charged particles in large multidetector gamma-arrays as EUROBALL is presented. The design is based on a N = 42 ball with 12 pentagons and 30 hexagons as used in the GASP array. The absorptive material for gamma-rays is minimized to the detector thickness of 300 or 500 mu m and a 0.63 mm ceramic backing. The geometrical coverage is desi

Palaeoenvironments, palaeoecology and palaeobiogeography of Late Cretaceous (Campanian) faunas from the Kristianstad Basin, southern Sweden, with applications for science education

I den andra delen av avhandlingen introduceras några konkreta förslag på tillämpningar av paleontologisk kunskap generellt, och forskningsresultat om fossil från Kristianstadsområdet specifikt, som kan användas i undervisning från förskola till gymnasieskola med undervisningsförslag inom de tre områdena; fossil och dinosaurier i förskolan, tidslinjer för utveckling av tidsmedvetenhet samt geovetenThis thesis is thematically divided into two sections: Part1 presents studies related to the palaeoenvironments,palaeoecology and palaeobiogeography of the LateCretaceous (Campanian) faunas from the KristianstadBasin of southern Sweden; Part 2 reports on applicationsof palaeontological research for science education inschools.Part 1 was based on personally conducted fieldworkand biostratigraphical

Health-related quality of life in children with Type 1 diabetes: an RCT of hospital-based care and hospital-based home care at diagnosis

Introduction: When a child is diagnosed with Type 1 diabetes, it involves extensive lifestyle changes for the whole family. There is limited knowledge of the impact the initial care has for children and parents over time. The aim was to compare children’s diabetes-specific health-related quality of life (HRQOL) in hospital-based care and hospital-based home care (HBHC), 12 and 24 months after the

Comparison of exhaustion symptoms in patients with stress-related and other psychiatric and somatic diagnoses

BACKGROUND: Several rating scales assessing stress-related symptoms of exhaustion have emerged in recent years. However, more knowledge is needed about the performance of these rating scales in patients with stress-related disorders as well as in other patient groups. With the recently developed Karolinska Exhaustion Disorder Scale (KEDS), we compared symptoms of exhaustion in different patient gr

Exhibiting transparency without opening the 'Black Box' - Balancing act between Data Protection and Trade Secrets Rights in Solely Automated Decision-Making AI system in Healthcare

What was once called science fiction has developed over the years to be one of the most strategic technologies of the 21st century – artificial intelligence (AI) is real. The rapid digitalization has opened new pathways in Swedish healthcare, by increasing productivity and the effectiveness of care delivery as well as helping more patients in receiving better care. Yet, when fully automated decisi