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Over the years poverty and well-being has taken several definitions. Recently, a wide literature unanimously agrees that the multidimensional aspects poverty such as economic, cultural, social and ecological has close linkages to lack of access to modern energy such as electricity or energy poverty. Thus, a focus on electricity for instance would be one possible mechanism of addressing multi-dimen
The proprietor of a copyright protected work has an economical right to make the work available to the public. The most significant form of making a work available in today’s information society is the right of communicating the work to the public. This is specifically regulated in article 3.1 in the Infosoc Directive and was implemented in 2 § URL in 2005. Especially this regulation pertains to t
I skrivande stund är sju olika cancercentra i Sverige, däribland Skånes Universitetssjukhus i Lund, mitt uppe i en gemensam randomiserad studie som undersöker behandling av prostatacancer med två olika strålningsscheman. Patienterna i studien blir slumpvis tilldelade antingen en standardbehandling, där de får en liten mängd strålning vid 39 olika tillfällen, eller en så kallad hypofraktionerad behPurpose: This work examined the feasibility of flattening filter free (FFF) volumetric modulated arc therapy (VMAT) for extreme hypofractionation of prostate cancer. The aim was to investigate the potential gain in treatment time per fraction for extreme hypofractionation of prostate cancer, while preserving or improving the treatment plan quality and radiation delivery quality. The impact of intr
Purpose: The Catalyst TM is a non-ionizing and non-invasive optical scanning system that has attractive features for patient setup and monitoring, as well as for respiratory gating during, radiotherapy treatments. In this study, the conventional laser based setup was compared with the surface based setup by the CatalystTM. A new non-rigid algorithm was used taking the whole planning target volume 60 00 cancerfall rapporteras in varje år till socialstyrelsen men där numera fler än hälften botas. Detta eftersom vi blir skickligare inom området och nya behandlingstekniker utvecklas. Rektalcancer, även kallat ändtarmscancer är en cancerform som ökat under de senaste decennierna. Behandling av patienter med rektalcancer varierar beroende på var och i vilket stadie tumören befinner sig i. Oftast
The reliable operation of nuclear reactors is contingent upon precise control mechanisms for critical components, such as the head circulation pumps. This master thesis investigates an innovative approach to address the ramp-down speed of these pumps during external electrical grid failures by exploring the application of a supercapacitor group. Presently, the existing solution relies on a fly-whe
Society is undergoing a great transformation with regard to the climate crisis, where electrification plays a crucial role in decarbonizing. To meet the future energy demand, improving power grid utilization is essential. This thesis develops standardized methods to evaluate and identify key parameters in terms of impact and branch loading, and to determine the probability of load flow scenarios u
“Men from March, women from Venus” is a bachelor thesis where the Swedish populations consumption habits of the product groups clothes, underwear and shoes are individually examined through statistical analysis. The aim of the thesis is to examine if any differences between male and female consumption of those product groups can be determined for the first year of the financial crisis. This is det
In case of alcohol situations on work places, there are lots of different expressions and definitions as alcohol abuse, alcoholism, chronic alcoholism, alcohol disease, occasional cases of alcohol abuse and alcohol abuse of disease character. The purpose with this paper is to investigate which value different definitions of alcohol problems has got in connection to employers rehabilitation respons
Popular Abstract in Swedish Denna avhandling behandlar modellsystem för farmaka som har DNA och RNA som mål i cellen. Framförallt behandlar den hur strukturen hos DNA och RNA påverkas av inbindning av olika substanser, samt hur fort denna inbindning sker. Tre olika typer av farmaka behandlas: 1. Platinaföreningar som länge använts som cytostatika, 2. RNA interferens som främst har utvecklats undDrugs targeting nucleic acids were studied in DNA and RNA model systems. The effects were investigated with respect to structural and thermodynamic influence, kinetics, and biological function. The drugs employed in this thesis were anticancer active platinum(II) complexes, polyamine derivatives, and siRNA. Structural changes were determined by use of chemical probing and circular dichroism (CD),
To elucidate the relationship between cerebrospinal fluid (CSF) total-tau (T-tau) and phosphorylated tau (P-tau) with the tau PET ligand 18F-AV-1451 in Alzheimer's disease (AD), we examined 30 cognitively healthy elderly (15 with preclinical AD), 14 prodromal AD, and 39 AD dementia patients. CSF T-tau and P-tau were highly correlated (R = 0.92, P < 0.001), but they were only moderately associated
Background: A parental mental illness affects all family members and should warrant a need for support. Aim: To investigate the extent to which psychiatric patients with underage children are the recipients of child-focused interventions and involved in interagency collaboration. Methods: Data were retrieved from a psychiatric services medical record database consisting of data regarding 29,972 in
Objectives: The aim of this study was to evaluate our experience with patients affected by ovarian carcinosarcoma. Patients and Methods: During a 16-year period, data on 13 patients with ovarian carcinosarcoma were collected. They were obtained from hospital charts and follow-up visits. Survival curves were estimated by the Kaplan-Meier method and compared using the log-rank test. All tests were t
Background: The WHO and the World Bank ask countries to report the national volume of surgery. This report describes these data for Sweden, a high-income country. Methods: In an 8-year population-based observational cohort study, all inpatient and outpatient care in the public and private sectors was detected in the Swedish National Patient Register and screened for the occurrence of surgery. The
Introduction: Lactate concentration is known to be a strong predictor of mortality, but is not included in any of the major intensive care scorings systems such as the Simplified Acute Physiology Score (SAPS 3). The objective of this study was to investigate the prognostic value of lactate concentration when combined with SAPS 3. Materials and methods: In the period of 2008 to June 2017 the genera
Shrunken pore syndrome (SPS) is defined by a cystatin C-based estimation of glomerular filtration rate (eGFRCYS) being less than 60% or 70% of a creatinine-based GFR estimation (eGFRCR) in the absence of extrarenal influences on cystatin C or creatinine concentrations. SPS has been associated with a substantial increase in mortality or morbidity in all investigated populations. However, in these s
Development of a new reduced chemical kinetic reaction mechanism for kerosene-air combustion is presented. The new mechanism uses a modular based development technique and is a further development on previously presented kerosene-air mechanisms. The new mechanism consists of 30 species and 77 irreversible reactions and is developed to accurate reproduce key flame parameters yet being small enough
Antisynthetase syndrome (ASSD) is a rare clinical condition that is characterized by the occurrence of a classic clinical triad, encompassing myositis, arthritis, and interstitial lung disease (ILD), along with specific autoantibodies that are addressed to different aminoacyl tRNA synthetases (ARS). Until now, it has been unknown whether the presence of a different ARS might affect the clinical pr
Ett fiskbestånd syftar på en grupp artfränder som uppehåller sig inom ett avgränsat område och som huvudsakligen parar sig sinsemellan, vilket medför att de genetiska likheterna är större inom ett bestånd än mellan separata bestånd. Denna beskrivning stämmer väl in på sjölevande fiskarter, där fisk sällan kan röra sig mellan sjöar, vilket alltså leder till genetiska skillnader mellan bestånd i oliPrudent management of marine fish resources relies on separation and management of biologically meaningful groups of conspecifics, termed fishery stocks, often depicted as self-sustaining, spatiotemporally separated and demographically independent entities. Such stock discrimination has however proven challenging. Although most marine fish species form local spawning populations (in relation to hy
Background: Postoperative nausea and vomiting (PONV) is common after general anaesthesia, and corticosteroids are used in many protocols for enhanced recovery after surgery (ERAS). However, surgical techniques are developing, and ERAS protocols need to be reevaluated from time to time. Patients and method: In this study, we compared the effects of oral vs. parenteral corticosteroid administration
