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A large part of the hunt for safety within the healthcare domain seems to be about hunting errors and trying to develop barriers to prevent similar errors in the future, learning from errors. People are seen as the liability and they should try harder to be safe. This study focuses on trying to understand how nurses create safety within the work instead of looking at the errors produced, learni
There has been much work on classification of malaria infected blood; in resent time, a method using LED-based microscopy has been developed with the goal of reducing time and cost. The education level needed to make such decisions is also reduced using this microscope. This is mainly done to help the developing countries in the fight against malaria and develop these countries competence in the f
I skrivande stund är sju olika cancercentra i Sverige, däribland Skånes Universitetssjukhus i Lund, mitt uppe i en gemensam randomiserad studie som undersöker behandling av prostatacancer med två olika strålningsscheman. Patienterna i studien blir slumpvis tilldelade antingen en standardbehandling, där de får en liten mängd strålning vid 39 olika tillfällen, eller en så kallad hypofraktionerad behPurpose: This work examined the feasibility of flattening filter free (FFF) volumetric modulated arc therapy (VMAT) for extreme hypofractionation of prostate cancer. The aim was to investigate the potential gain in treatment time per fraction for extreme hypofractionation of prostate cancer, while preserving or improving the treatment plan quality and radiation delivery quality. The impact of intr
Swedish office buildings of the 60’s present at least 27% higher heating demand than from the current standards foreseen. This underlines their need for energy renovation. Meanwhile, office buildings are occupied during daytime, thus internal and solar gains are in phase. Consequently, such buildings could experience overheating problems. A seasonal adaptable envelope, such as a ventilated double
The Global Compact on Refugees, which is to be adopted in the autumn of 2018, represents an aspiration on the part of the international community towards strengthened solidarity with refugees and affected host countries and is the most ambitious instrument of its kind to date. Indeed, the creation of the Refugee Compact is timely, although perhaps also somewhat surprising in an era of rising popul
Popular Abstract in Swedish Inledning/introduktion: Öppen rekonstruktion av aorta innebär en påtaglig risk för postoperativa komplikationer och dödlighet, särskilt i den äldre befolkningen och i dem som är mindre lämpliga för en sådan stor operation. Endovaskulär aorta kirurgi förefaller säker, hållbar och effektiv när det finns tillräcklig proximal och distal tätningszon för en stentgraft. FenestIntroduction: Open repair of the aorta carries a high risk for morbidity and mortality especially in the elderly population and in patients unfit for major surgery. Endovascular aortic repair is safe, durable and effective when there is adequate proximal and distal sealing zone for the aortic stent graft. Fenestrated and branched stent grafts have made the repair possible for complex but elective
Purpose: Chronic rhinosinusitis (CRS) is related to asthma and chronic obstructive pulmonary disease (COPD). However, combined data on CRS, pulmonary function, lower airway symptoms, and cigarette smoking from the general population are lacking. The current study investigates the relationships between CRS and chronic airflow limitation (CAL), lower airway symptoms and COPD in a middle-aged populat
Background: Tamoxifen is an established treatment for breast cancer, but its long-term effects on survival and on secondary cancers are not fully evaluated. Material and methods: We studied 30 years outcome of 4124 postmenopausal patients who were randomized to receive (totally) two or five years of adjuvant tamoxifen. Results: After 5 years of follow-up, when tamoxifen treatment was finished in b
Background: Traumatic brain injury causes morbidity, mortality, and at least 2,500,000 yearly emergency department visits in the USA. Computerized tomography of the head is the gold standard to detect traumatic intracranial hemorrhage. Some are not diagnosed at the first scan, and they are denoted “delayed intracranial hemorrhages. ” To detect these delayed hemorrhages, current guidelines for head
Introduction: Treatment of Graves´ disease (GD) with radioiodine increases the risk of developing Graves´ ophthalmopathy (GO), and the link between thyroid and orbital tissue may be the presence of TSH-receptors. Radioiodine increases the titers of TRAb and the aim was to investigate the relationship between GO and TRAb titers after treatment with radioiodine and to define the impact of risk genes
Objective To explore timing in relation to all types of adverse events (AEs), severity and preventability for patients undergoing acute and elective hip arthroplasty. Design A multicentre cohort study using retrospective record review with Global Trigger Tool methodology in combination with data from several registers. Setting 24 hospitals in 4 major regions of Sweden. Participants Patients ≥18 ye
Aim: The increasing spread of vector-borne diseases has resulted in severe health concerns for humans, domestic animals and wildlife, with changes in land use and the introduction of invasive species being among the main possible causes for this increase. We explored several ecological drivers potentially affecting the local prevalence and richness of avian malaria parasite lineages in native and
INTRODUCTION: The prognosis for patients with melanoma has improved due to better treatments in recent years and updated tools to accurately predict an individual's risk are warranted. This study aims to describe a prognostic instrument for patients with cutaneous melanoma and its potential as a clinical device for treatment decisions.METHODS: Patients with localised invasive cutaneous melanoma di
Ineffective antimicrobial therapy of Pseudomonas aeruginosa bacteraemia increases mortality. Recent studies have proposed the use of antimicrobial combination therapy composed of a beta-lactam with either ciprofloxacin or tobramycin. To determine if combination therapy correlates to lower mortality and is superior compared to monotherapy, we investigated the effect of antimicrobial treatment regim
BACKGROUND: Multisite pain and obesity are cross-sectionally related and are common conditions that may influence each other through socio-demographic, lifestyle and/or health-related factors. The aim of the present study was to examine the cross-sectional and prospective associations between overweight/obesity and multisite pain in a general population.METHODS: In a 20-year population-based prosp
The association between socioeconomic circumstances and incidence of chronic obstructive pulmonary disease (COPD) was investigated in an urban population in Sweden. The study included all 40–89 year-old inhabitants in Malmö, Sweden (N = 117,479) without previous hospitalization due to COPD, who were followed over 14 years for COPD related hospital admissions. The Malmö Preventive Project (MPP) co
OBJECTIVE: We sought to assess the value of adjusting shunt valve opening pressure, complications, and outcomes with the use of an adjustable shunt valve in the treatment of patients with normal-pressure hydrocephalus (NPH). METHODS: In a single-center retrospective study, 231 adjustable valves (range, 30-200 mm H2O) were the first shunt implantations in 147 patients with idiopathic NPH (INPH) and
Accurate methods to preoperatively characterize adnexal tumors are pivotal for optimal patient management. A recent meta-analysis concluded that the International Ovarian Tumor Analysis (IOTA) algorithms such as the Simple Rules are the best approaches to preoperatively classify adnexal masses as benign or malignant. We sought to develop and validate a model to predict the risk of malignancy in ad
Alternative C activation is involved in the pathogenesis of ANCA-associated vasculitis. However, glucocorticoids used as treatment contribute to the morbidity and mortality of vasculitis.We determined whether avacopan (CCX168), an orally administered, selective C5a receptor inhibitor, could replace oral glucocorticoidswithout compromising efficacy. In this randomized, placebo-controlled trial, adu
This thesis deals primarily with the production of written texts by adults with reading and writing difficulties. Their writing is analysed from three different aspects: error analysis, non-error-oriented text analysis and analysis of the production process. These studies are based on data from on-line recordings of writing. The main question is how the written language production of adults with r
