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Telomeres are the ends of linear eukaryotic chromosomes. The telomeres are essential for solving the end replication problem and they stabilize the genome by protection from degradation. The telomeres also protect the chromosomal ends from by being recognized as DNA breaks by the repair machinery, which could lead to end-to-end fusions. Dysfunctional telomeres are implicated in many complex cellul
Recent research using repeat photography, long-term ecological monitoring and dendrochronology has documented shrub expansion in arctic, high-latitude and alpine tundra ecosystems. Here, we (1) synthesize these findings, (2) present a conceptual framework that identifies mechanisms and constraints on shrub increase, (3) explore causes, feedbacks and implications of the increased shrub cover in tun
This work presents an analysis of the physical properties of sub-micrometer aerosol particles measured at the high Arctic site Villum Research Station, Station Nord (VRS), northeast Greenland, between July 2010 and February 2013. The study focuses on particle number concentrations, particle number size distributions and the occurrence of new particle formation (NPF) events and their seasonality in
The interactions of the anionic bile salt NaGDC with three triblock copolymers based on poly(ethylene oxide) (PEO) and poly(propylene oxide) (PPO), denoted P65, P123 and F127, were investigated using high-sensitive differential scanning calorimetry (DSC), turbidimetry, dynamic and static light scattering and small angle X-ray scattering (SAXS). P65 and P123 had the same hydrophilic PEO block lengt
The aim of this article is to explore how new industrial paths emerge and grow in peripheral regional economies. Current conceptualizations of regional path development are based on experiences from core regions and fail to provide satisfactory theoretical explanations of new path-creating activities in peripheral areas. Our conceptual approach combines the notions of path development and knowledg
Thin ion transmission detectors can be used as a part of a telescope detector for mass and energy identification but also as a pre-cell detector in a microbeam system for studies of biological effects from single ion hits on individual living cells. We investigated a structure of graphene on silicon carbide (SiC) with the purpose to explore a thin transmission detector with a very low noise level
We investigate the star formation-feedback cycle in cosmological galaxy formation simulations, focusing on the progenitors of Milky Way (MW)-sized galaxies. We find that in order to reproduce key properties of the MW progenitors, such as semi-empirically derived star formation histories (SFHs) and the shape of rotation curves, our implementation of star formation and stellar feedback requires (1)
Reactions of 4-thio-2′-deoxyuridine d(s4U) and 4-thiouridine 5′-monophosphate s4UMP with trans-[AuY2Cl2]+/– (Y = CN– or NH3) have been investigated by conventional and high-pressure stopped-flow spectrophotometry in aqueous solution with 2.9 ⩽ pH ⩽ 7.0. For a given combination of metal complex and sulfur donor the observed second-order rate constants decreased with increasing pH. In the pH range 2
Food processing comprises operations such as dilution (changing the concentration), homogenisation (changing the particle size), and subsequent pumping (shearing), among others. It is thus of great interest to gain a better understanding of the mechanisms governing the creation and disruption of structures during these engineering operations, and the way in which they are related to the textural a
On closer inspection, the so-called iconic turn in recent media history is a multimodal turn. Media communication has not only been enriched by pictures but has turned from a text-medium into a multi-medium, i.e. into a complex system of different modes like design, colours, pictures, graphics, and typography. Along with the multimodal turn, the linear structure of media communication has become n
BACKGROUND: The Swedish school-based vaccination programme offers HPV vaccine to girls born ≥1999 in 5-6th grade. In 2012, all counties introduced free-of-charge catch-up vaccination campaigns targeting girls born 1993-1998. Varying vaccine uptake in the catch-up group by December 2012 suggested that some implementation strategies were more successful than others. In order to inform future vaccina
The rat and human recombinant soluble and membrane-bound catechol O-methyltransferase (S- and MB-COMT, respectively) were expressed using mammalian and baculovirus vectors. Low levels of rat and human S-COMT polypeptides were detected by immunoprecipitation in K-562 cell lines transfected with the S-COMT vectors. From K-562 cells transfected with the rat MB-COMT construct, both S- and MB-COMT reco
Oxytocin (OT) and vasopressin (VP) are neurohypophyseal hormones with potent stimulatory actions on the uterus. In order to determine whether these hormones may have a paracrine action on the uterus, OT and VP gene expression was studied in myometrium from pregnant rats at gestational ages of 14 and 20 days, and from ovariectomized animals treated with oestradiol and progesterone. OT and VP mRNA c
Large-scale protein conformational motions on nanosecond – microsecond time scales are important for many biological processes, but remain largely unexplored because of methodological limitations. NMR relaxation methods can access these time scales if protein tumbling is prevented, but the isotropy required for high-resolution solution NMR is then lost. However, if the immobilized protein molecule
The key step in the reaction mechanism of multicopper oxidases (MCOs)-the cleavage of the O-O bond in O-2-has been investigated using combined quantum mechanical and molecular mechanical (QM/MM) methods. This process represents a reaction pathway from the peroxy intermediate after it accepts one electron from the nearby type-1 Cu site to the experimentally-observed native intermediate, which is th
The oxidation of biogenic volatile organic compounds (BVOCs) gives a range of products, from semi-volatile to extremely low-volatility compounds. To treat the interaction of these secondary organic vapours with the particle phase, global aerosol microphysics models generally use either a thermodynamic partitioning approach (assuming instant equilibrium between semi-volatile oxidation products and
Utbildningar & studentliv LUNDS UNIVERSITET LUND–MALMÖ–HELSINGBORG | 2017/18 Innehåll: Varför ska du välja Lunds universitet? ............................. 5 Välkommen till ett universitet i världsklass .................... 6 Att läsa på Lunds universitet ........................................... 8 Sveriges roligaste studentstad är tre ............................. 10 Ett studentliv för alla ...
https://www.lu.se/sites/www.lu.se/files/lu_utbildningsmagasin_2017_18.pdf - 2026-05-20
Brevmall 2 General syllabus for third-cycle studies for the degree of Doctor in Human Geography/Economic Geography and Geography specialising in Human Geography The syllabus was approved by the Board of the Faculty of Social Sciences on 31 May 2007, reg. no G 11 S 2007/216. 1 Subject description Research at the Department of Human Geography has three specialisations: Human Geography (focusing on u
https://www.keg.lu.se/en/sites/keg.lu.se.en/files/dok2.doc - 2026-05-20
SOU 2017:39 Dataskyddsutredningen Stockholm 2017 SOU 2017:39 Betänkande av Dataskyddsutredningen Ny dataskyddslag Kompletterande bestämmelser till EU:s dataskyddsförordning SOU och Ds kan köpas från Wolters Kluwers kundservice. Beställningsadress: Wolters Kluwers kundservice, 106 47 Stockholm Ordertelefon: 08-598 191 90 E-post: kundservice@wolterskluwer.se Webbplats: wolterskluwer.se/offentligapub
https://www.medarbetarwebben.lu.se/sites/medarbetarwebben.lu.se/files/sou-ny-dataskyddslag-maj2017.pdf - 2026-05-20
