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OBJECTIVE: Treatments have failed to delay or stop the autoimmune process, preceding onset of type 1 diabetes. We investigated if autoantigen-specific treatment with alum-formulated glutamate decarboxylase (GAD-Alum) was safe and affected progression to type 1 diabetes in children with islet autoimmunity.METHODS: In an investigator-initiated, double-blind, placebo-controlled clinical trial, non-di

Proton exchange membrane (PEM) fuel cells have been promoted due to significant breakthroughs in various aspects and increasing public interests. The porous features of the gas diffusion layer (GDL) and the necessary assembly processes generate localized pressure forces on the channel/shoulder structure of the bi-polar plates (BPP). As a consequence, the assembly pressure acting on a single cell a

B cells are thought to play a central role in the pathogenesis of antineutrophil cytoplasmic antibody- (ANCA-) associated vasculitis (AAV). ANCAs have been proposed to cause vasculitis by activating primed neutrophils to damage small blood vessels. We studied a cohort of AAV patients of which a majority were in remission and diagnosed with granulomatosis with polyangiitis (GPA). Using flow cytomet

This review aims to provide a comprehensive overview of the in vitro, animal, and clinical studies with the bacterial strain Lactiplantibacillus plantarum 299v (L. plantarum 299v; formerly named Lactobacillus plantarum 299v) published up until June 30, 2020. L. plantarum 299v is the most documented L. plantarum strain in the world, described in over 170 scientific publications out of which more th

Purpose: The aim of this study was to assess the suitability of Gafchromic EBT3 films for reference dose measurements in the beam of a prototype high dose-per-pulse linear accelerator (linac), capable of delivering electron beams with a mean dose-rate (Dm) ranging from 0.07 to 3000 Gy/s and a dose-rate in pulse (Dp) of up to 8 × 106 Gy/s. To do this, we evaluated the overall uncertainties in EBT3

Agricultural intensification and its effect on spiders and their prey Spiders are abundant predators that can be very useful for biological control, as they eat insects that can damage crops. To study the potential of this group as biocontrol agents it is necessary to understand the trophic relationships and the factors that affect the distribution of both spiders and their prey. For this purpos

Optokinetic reflex in chickens Vision is the most important sense for many birds. Birds use their vision for many different tasks like finding food, spotting potential mates and predators. They also use this very important sense to navigate and move through the environment, and this is interpreted by the visual system as self-motion. The visual system divides properties of the environment into di

De s.k. fåmansföretagsreglerna i 57 kap. IL syftar till att motverka att aktiva delägare omvandlar arbetsinkomster till lägre beskattade kapitalinkomster. När utomstående passiva delägare äger viss andel av bolaget blir en inkomstomvandling inte längre fördelaktig. I 57 kap. 5 § finns därför en undantagsregel från de särskilda beskattningsreglerna i 57 kap. IL, den s.k. utomståenderegeln. Om incitThe 3:12 rules, found in Chapter 57 of the Swedish Income Tax Act (1999:1229), consists of special tax rules which apply to active owners in closely held corporations (fåmansföretag). The rules aim to prevent active owners from transforming salary income into lower taxed capital income. If passive owners have an ownership of at least 30 % of the shares, income shifting is no longer beneficial. The

Integration of machine operators in nature conservation – A demand for education In Swedish forestry there are several educational programs that provides certificates in nature conservation and environmental considerations for machine operators (Blue & Green). The certificates are optional, but if a machine operator intends to work in licensed forests with a higher nature consideration, the c

Transporten i och genom de biologiska membranerna är väldigt viktig och har många applikationer i mat- och läkemedel industrier. Dessa membranerna består av dubbel-lager av lipid molekyler. Genom att blanda två olika sorter av lipiderna diglycerolmonooleate (DGMO) och glycerol monooleate (GMO-50) med nano-partikelstabilisatorpolysorbate 80 (P80) i överskott av vatten skapar det en lipidblandning m

A model is used to describe a system physically or mathematically and to give information about changes in the system variables. Physical knowledge about the system and its quantities can be useful to build a physical model obeying the laws of nature. However, if the system is to be regarded as a black box with only input and output signals, system identification can be used to fit a mathematical

Under de senaste 30 åren har en ny metod för att få information om tidigare ekosystem utveck- lats, nämligen att analysera gammalt (“ancient”) DNA (aDNA). Denna forskningsgren är fortfarande ung men har redan hittat många områden inom vilka den kan tillämpas. Inom paleoekologin finns det två huvudsakliga ändamål med aDNA-analyser; att kartlägga en arts hela genom, samt att bestämma antal taxa och During the last 30 years a new method for obtaining information about past ecosystems has been devel- oped, namely to analyse old (“ancient”) DNA (aDNA). This research field is still young but has already found many areas within which it can be applied. In palaeoecology, there are two main purposes with aDNA analyses; to map the entire genome of a species, and to determine the number of taxa, and

Skadliga marina arter invaderar idag främmande habitat och ekosystem med en extrem hastighet. Dessa arter har haft en mycket stor negativ inverkan på många sårbara ekosystem runt om i världen och barlastvatten har identifierats som en av de största faktorerna bakom den snabba spridningen. Idag är den vanligaste åtgärden för att lösa problemet att byta barlastvatten ute till havs för att göra sig aHarmful aquatic species are today invading foreign habitats at an unprecedented pace. They have had a large negative impact on many fragile ecosystems of the world and ballast water has been identified as one the major culprits behind their fast spread. Today, the most common remedy used to combat the problem is exchanging ballast water in the open ocean to get rid of any organisms with the potent

Popular science summary: The European silver eel oceanic migration During the past 30 years the population of the European silver eel has been declining dramatically. This is a commercially important species and several action plans have been established but little information about the biology of the European eel is known. During the EELIAD project female silver eels were electronically tagged

Popular science summary Are drugs only drugs for human being? An experiment to see if some of the anthropogenic pharmaceuticals are toxic contaminants for the aquatic environment. All kinds of pharmaceuticals have been using widely and the amount has been increased significantly during the last few decades. Concerns about the occurrence of pharmaceuticals releasing into different matrixes of th

Sammanfattning Instansordningsprincipen är en förvaltningsrättslig princip som huvudsakligen medför att parterna i ett förvaltningsmål är förhindrade att tillföra nytt processmaterial i högre instanser. Principen är, emellertid, inte uttryckligen lagstadgad i Förvaltningsprocesslagen (1971:291), FPL. Istället är det upp till förvaltningsdomstolarna att tolka de uttalande som finns i förarbetena tiSummary The principle of the court hierachy is a principle within administrative law whose intention is to prevent the parties to add new case material in the higher instances. The principle, however, is not explicitly stated in the Administrative Court Procedure Act (1971: 291), FPL. Instead, the administrative courts are given the task to interpret various statements contained in the legislative

Abstract Perforations are one of Tetra Paks oldest inventions of how to open their carton packages. They have been a part of Tetra Briks product portfolio for over 30 years and quality testing is important. Bad openability, with plastic residues covering the torn hole, is a problem that needs to be addressed. When tearing a package with perforation all people do it differently. By using a mechan

Populärvetenskaplig sammanfattning: Småvatten är en svacka eller hålighet som är vattenfylld året om. Dessa småvatten fyller många viktiga funktioner i naturen. De fungerar som utjämnare av flödesvariationer, uppehållsplats och födoplats för många djur och växter och som rena estetiska inslag i naturen, och inte minst som reningsplatser för oönskade näringsämnen så som kväve. Dessa småvatten har iWetlands play an important role in the ecosystem. They reduce the impact of flow flux in the drainage area, acts as upholder of biodiversity, as an esthetic and recreational component in the landscape and they have the ability to reduce nutrients such as nitrogen, and help preventing eutrophication in costal areas. The number of wetlands in Scania have, due to the intensified agriculture been redu

Context. Ultra-hot Jupiters present a unique opportunity to understand the physics and chemistry of planets, their atmospheres, and interiors at extreme conditions. WASP-12 b stands out as an archetype of this class of exoplanets, with a close-in orbit around its star that results in intense stellar irradiation and tidal effects. Aims. The goals are to measure the planet's tidal deformation, atmos

AbstractThe phonetics of NCh in Tumbuka and implications for diachronic change Fonologi i Norden 2018 (FiNo 2018) Program Updated: 2018-02-05 FRIDAY, FEBRUARY 9 (6 TALKS) 13.30-14.10 Laura Downing & Silke Hamann “Investigating the diachronic fate of NTh in Bantu languages” 14.10-14.50 Bert Botma, Janet Grijzenhout & Camilla Horslund “Voice and noise don’t mix: voiced fricatives in Nordic languages

https://konferens.ht.lu.se/fileadmin/user_upload/sol/ovrigt/konferens_fino2018/FiNo2018-ProgramAbstracts.pdf - 2026-05-23