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Purpose: To assess the performance of activities of daily living (ADL) in individuals with moderate to severe multiple sclerosis (MS). Method: A total of 12 men and 32 women with MS ( Expanded Disability Status Scale, EDSS, 6.0-8.5) were studied. The performance of personal ADL (P-ADL) and instrumental ADL (I-ADL) was assessed with the Functional Independence Measure (FIM) and the Assessment of Mo
Light detection and ranging (LIDAR) experiments are normally pursued for range resolved atmospheric gas measurements or for analysis of solid target surfaces using fluorescence of laser-induced breakdown spectroscopy. In contrast, we now demonstrate the monitoring of free gas enclosed in pores of materials, subject to impinging laser radiation, employing the photons emerging back to the surface la
The pairing correlations of the nucleus 120Sn are calculated by solving the Nambu–Gor’kov equations, including medium polarization effects resulting from the interweaving of quasiparticles, spin and density vibrations, taking into account, within the framework of nuclear field theory (NFT), processes leading to self-energy and vertex corrections and to the induced pairing interaction. From these r
Peptide oligomerization dynamics affects peptide structure, activity, and pharmacodynamic properties. The thrombin C-terminal peptide, TCP-25 (GKYGFYTHVFRLKKWIQKVIDQFGE), is currently in preclinical development for improved wound healing and infection prevention. It exhibits turbidity when formulated at pH 7.4, particularly at concentrations of 0.3 mM or more. We used biochemical and biophysical a
Governance of common resources such as water calls for rethinking structure, legal frameworks and property rights. In order to promote the decentralization of water governance, Water User Associations (WUAs) were created in many countries, such as India and Turkey, to operate and maintain irrigation systems as well as take over the responsibility of water distribution among water users. Despite pr
The current research focuses in understanding how inlet pressure, EGR, combustion phasing, engine speed and pilot main ratio are affecting the main parameters of the combustion (e.g. efficiency, NOx, soot, maximum pressure rise rate) in the novel concept of injecting high octane number fuels in partially premixed combustion. The influence of the above mentioned parameters was studied by performing
Vehicle-to-vehicle (V2V) wireless communications can improve traffic safety at road intersections and enable congestion avoidance. However, detailed knowledge about the wireless propagation channel is needed for the development and realistic assessment of V2V communication systems. We present a novel geometry-based stochastic MIMO channel model with support for frequencies in the band of 5.2-6.2 G
This study investigates machining superalloy Inconel 718 with polycrystalline cubic boron nitride (pcBN) tooling both numerically and experimentally. Particular attention is given to mechanical and thermal stresses in the cutting tool arising from segmented chip formation and associated forces and temperatures. The temperature dependence of the mechanical properties of pcBN has been investigated a
An experiment was conducted to follow the fate of the cyanobacterial toxin, nodularin, produced by Nodularia spumigena through ingestion by Mytilus edulis and re-ingestion of faecal material (coprophagy). Mussels were fed with cultures of N. spumigena, and the faeces that were produced were fed to other mussels not previously exposed to N. spumigena. Concentrations of nodularin were measured in th
Oppenheimer describes The Act of Killing as a ‘documentary about the imagination. We are documenting the ways we imagine ourselves, the ways we know ourselves’. This research analyses the documentary films The Act of Killing (Director Oppenheimer, co-directors Christine Cynn and anonymous 2012) and The Look of Silence (director Oppenheimer 2014), and the documentary imaginary. The research combine
How do donors reason and justify their choices when faced with dilemmas in a charitable context? In two studies, Swedish students were confronted with helping dilemmas based on the identifiable victim effect, the proportion dominance effect and the ingroup effect. Each dilemma consisted of two comparable charity projects and participants were asked to choose one project over the other. They were t
Directed colloidal self-assembly at fluid interfaces can have a large impact in the fields of nanotechnology, materials, and biomedical sciences. The ability to control interfacial self-assembly relies on the fine interplay between bulk and surface interactions. Here, we investigate the interfacial assembly of thermoresponsive microgels and lipogels at the surface of giant unilamellar vesicles (GU
Pre-eclampsia is a pregnancy complication characterized by hypertension and proteinuria. There are several factors associated with an increased risk of developing pre-eclampsia, one of which is increased uterine artery resistance, referred to as "notching". However, some women do not progress into pre-eclampsia whereas others may have a higher risk of doing so. The placenta, central in pre-eclamps
Issues of quality, value, and merit are perpetually lively and contentious in scientific and academic work, and research on evaluation panels have shown that organizational constraints and the methods of evaluation used, whether well-motivated or adopted ad hoc, have enormous influence on outcomes. But while previous studies have highlighted the influence exerted by particular methods of evaluatio
Epilepsy is a prevalent neurological disorder characterized by spontaneous recurrent seizures (SRS). Epileptogenesis is a multifaceted pathophysiological process that transforms a normal brain into one prone to chronic seizures. Targeting epileptogenesis is a compelling line of epilepsy therapy. Thus, discovering new drugs that oppose, mitigate, or modify epileptogenesis is a significant challenge
Understanding damage mechanisms and quantifying damage is important in order to optimise structures and to increase their reliability. To achieve this goal, experimental- and simulation-based techniques are to be combined. Different methods exist for the analysis of damage phenomena such as fracture mechanics, phase field models, cohesive zone formulations and continuum damage modelling. Assuming
Despite shrinking civic space, civil society organisations (CSOs) in Uganda continue to shape pathways toward sustainable and inclusive agricultural transformation. This paper explores why and how CSOs use non-confrontational strategies, particularly advocacy to influence policy and institutional processes regarding agricultural development. It draws on in-depth interviews with CSO actors, includi
This article elaborates on the notion of “decarbonisation by dispossession” in order to shed light on the contradictory character of capital-driven energy transitions. First, we suggest conceptualising “decarbonisation” as a “socio-ecological fix” to intersecting, climate-induced crises of accumulation and hegemony, aimed at saving capital rather than the planet. Second, reflecting on the mineral
This thesis consists of three essays in dynamic panel data econometrics. It studies the estimation of persistent dynamic relationships in panel models with unobserved heterogeneity and predetermined regressors, combining methodological contributions with an application in growth empirics.The first paper analyzes structural breaks in persistence in a dynamic panel first-order autoregressive model w
