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VIP potentiates cholinergic effects on the mucociliary system in the maxillary sinus

The neuropeptide vasoactive intestinal polypeptide (VIP), which is found in a population of cholinergic parasympathetic neurons in the airways, has no effects per se on mucociliary activity. In order to test the hypothesis that VIP may modulate cholinergic regulation of the mucociliary system, VIP was infused intraarterially (8.4 pmol/kg/min), and the response to challenges with methacholine in th

Integrated process for purification of plasmid DNA using aqueous two-phase systems combined with membrane filtration and lid bead chromatography

An integrated process for purifying a 6.1 kilo base pair (kbp) plasmid from a clarified Escherichia coli cell lysate based on an ultra/diafiltration step combined with polymer/polymer aqueous two-phase system and a new type of chromatography is described. The process starts with a volume reduction (ultrafiltration) and buffer exchange (diafiltration) of the clarified lysate using a hollow fibre me

Inhibitory properties of cystatin F and its localization in U937 promonocyte cells

Cystatin F is a recently discovered type II cystatin expressed almost exclusively in immune cells. It is present intracellularly in lysosome-like vesicles, which suggests a potential role in regulating papain-like cathepsins involved in antigen presentation. Therefore, interactions of cystatin F with several of its potential targets, cathepsins F, K, V, S, H, X and C, were studied in vitro. Cystat

Airway effects of salmeterol in healthy individuals

The long-acting beta 2-agonist salmeterol has been shown in several in vitro studies to produce non-beta-mediated relaxant effects. The aim of the present study was to investigate whether these effects have any relevance in humans in vivo. Thirteen healthy individuals were studied in a randomized, double-blind, cross-over study on five separate days. The subjects were pre-treated orally with eithe

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Abstract in Norwegian Bakgrunn. Fallulykker er et viktig helseproblem hos eldre. Både balansetesting og registrering av egenrapportert funksjon kan være måter å forutse fremtidige ulykker på. Materiale og metode. I en kohortstudie ble egenrapportert gangfunksjon kartlagt hos 307 tilfeldig utvalgte hjemmeboende kvinner 75 år og eldre. Kvinnene gjennomgikk også testing av balanse og gangfunksjon, oBACKGROUND: Falls represent an important health problem among the elderly. Balance testing as well as registration of self-reported balance problems may be appropriate in order to predict the risk of future falls. MATERIALS AND METHODS: Self-reported walking was assessed in 307 randomly selected women 75 years or older living at home. The women underwent testing of gait and balance and were follow

Arter av växter: Är de och vad är de?

The current confusion about what species are has two major causes. First, many authors discussing species concepts seem not to have considered for what purpose species are distinguished. Several proposed species concepts define species in a way that is only useful in a narrow field of advanced biological science. It is argued that species concepts should rather fulfil the needs of the majority of

Calculation of geomagnetically induced currents in the 400 kV power grid in southern Sweden

Sweden has experienced many geomagnetically induced current (GIC) events in the past, which is obviously due to the high-latitude location of the country. The largest GIC, almost 300 A, was measured in southern Sweden in the earthing lead of a 400 kV transformer neutral during the magnetic storm on 6 April 2000. On 30 October 2003, the city of Malmo at the southern coast suffered from a power blac

Space weather events in July 1982 and October 2003 and the effects of geomagnetically induced currents on Swedish technical systems

In this paper, we analyse in detail two famous space weather events; a railway problem on 13-14 July 1982 and a power blackout on 30 October 2003. Both occurred in Sweden during very intensive space weather storms and each of them a few years after the sunspot maximum. This paper provides a description of the conditions on the Sun and in the solar wind leading to the two GIC events on the ground.

Theoretical study of the unusual potential energy curve of the A (1)Sigma(+) state of AgH

The A (1)Sigma(+) potential energy curve of AgH is studied by means of the second-order multistate multireference perturbation theory including the spin-orbit and relativistic effects. The anomalous behavior of the vibrational energy levels observed in experiment is reproduced well by theory. An analysis of the A (1)Sigma(+) wave function shows that at the internuclear distance of 4-6 Angstrom, a

What is ideal genetic counselling? A survey of current international guidelines

The objective of this article is to review guidelines that address counselling in the context of genetic testing in order to summarise what aspects of counselling they consider most important, and to examine how they construct the ideal of genetic counselling. Guidelines were collected by examining the websites of different international professional, political, ethical and patient organisations,

Physical properties of the 2-amino-2-methyl-1-propanol and N-methyl-2-pyrrolidone system

A novel technique for CO2 removal using a precipitating amine absorption system is being studied for potential use in biogas upgrading and carbon capture and storage (CCS). The system uses the sterically hindered amine 2-amino-2-methyl-1-propanol (AMP) mixed in different concentrations with the organic solvent N-methyl-2-pyrrolidone (NMP). In the current work, the physical solubility of CO2 in sol

Att inte bli kriminell: en kvalitativ studie om unga studenters reflektioner kring faktorer i en uppväxt som är väsentliga för ett icke kriminellt handlande

Background:The research of social science tends in many cases lean towards an approach that focus on negatively influencing factors, rather than health promoting factors from a salutogenic perspective. In the field of criminology, this approach commonly investigates reasons behind criminal behavior instead of studying the salutogenic factors, i.e. reasons why people do not engage in a criminal lif

Crushing the lack of differentiation: An AHP-based inventory classification for Sandvik Rock Processing

Problem Statement: Sandvik Rock Processing is in the need for a classification tool, which can help them improve their inventory management. Currently, there are problems with inefficiencies with deficit as well as excess in inventory. The new classification shall the basis for the differentiation of service levels and facilitate a shared view on items’ importance. Purpose: The purpose of this th

Wfp internship vacancy announcement february 2017

17 January 2001 World Food Programme Programme Alimentaire Mondial Programa Mundial de Alimentos The Food Aid Organization of the United Nations Internship – World Food Programme Nordic Office From February 6th – August 11th 2017 Passionate about humanitarian and development assistance? Eager to see a world free from hunger in 2030? Looking to gain experience within communication and advocacy? ___

https://www.keg.lu.se/sites/keg.lu.se/files/wfp_internship_vacancy_announcement_february_2017.pdf - 2026-05-25

A Voyage to Vardø – A Scientific Account of an Unscientific Expedition

After the “Venus Transit Conference” that took place at the University of Tromsø from June 2 to June 3, 2012, participants were given the opportunity to either stay in Tromsø until the night of June 5–6, or to participate in a voyage to Finnmark, where the historical sites Vardø, Hammerfest, and the North Cape were to be visited. This voyage culminated in the observation of the 2012 transit of Ven

Filter Plate–Based Screening of MIP SPE Materials for Capture of the Biomarker Pro-Gastrin-Releasing Peptide

Affinity-based solid-phase extraction (SPE) is an attractive low-cost sample preparation strategy for biomarker analysis. Molecularly imprinted polymers (MIPs) as affinity sorbents offer unique opportunities for affinity SPE, due to their low manufacturing cost and high robustness. A limitation is the prediction of their affinity; therefore, screening of analyte recovery and specificity within a l

An automatic method for quantification of myocardium at risk from myocardial perfusion SPECT in patients with acute coronary occlusion.

BACKGROUND: In order to determine myocardial salvage, accurate quantification of myocardium at risk (MaR) is necessary. We present a validated novel automatic segmentation algorithm for quantification of MaR by myocardial perfusion SPECT (MPS) in patients with acute coronary occlusion. METHODS AND RESULTS: Twenty-nine patients with coronary occlusion were injected with a perfusion tracer before re

Correlates of Nine-Month Retention following Interim Buprenorphine-Naloxone Treatment in Opioid Dependence: A Pilot Study.

Interim medication-only treatment has been suggested for the initiation of opioid maintenance treatment (OMT) in opioid-dependent subjects, but this rarely has been studied using buprenorphine instead of methadone. Following a pilot trial assessing interim buprenorphine-naloxone treatment in order to facilitate transfer into OMT, we here aimed to study retention, and potential correlates of retent

Bleeding peptic ulcer - time trends in incidence, treatment and mortality in Sweden.

Abstract Background: The incidence of peptic ulcer disease was expected to decrease following the introduction of acid inhibitors and H. pylori eradication. Aim: This study analyses possible changes in the incidence of bleeding peptic ulcer, treatment and mortality over time. Methods: Residents of Malmö hospitalised for bleeding gastric or duodenal ulcer disease1987-2004 were identified in hospita