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Ubiquitination is a post-translational modification process that has a very important role in the homeostasis of eukaryotic cells. Linkage-specific ubiquitination determines the final destination of modified protein. Ubiquitination has also been reported to regulate inflammasome function and IL-1β degradation. Secretion of IL-1β by macrophages in response to inflammasome activation is a key proces
It is important to the recruitment company that only quality candidates, and the candidates most likely to receive an offer of employment get short-listed to go through the carriers selection process. It is this second phase of the recruitment process, the short-listing of potential candidates, that will be the focus of this thesis. Data has being gathered by the recruitment company through an i
Vattenkraft tillsammans med kärnkraft är dominerade energikällor i Sverige. Vattenkraften är till skillnad från kärnkraften en förnybar energikälla. Vattenkraften är vidare ett klimatvänligt energislag eftersom det inte orsakar koldioxidutsläpp under drift. Dessutom har vattenkraften unika förmågor som regler- och lagringskraft, vilket innebär en stor trygghet för Sveriges energisystem och samhällSweden has received criticism for insufficient implementation of the European Water Framework Directive (WFD). The quality of Swedish water does not meet the conditions according to the EU. Hydropower is a climate friendly and important energy source, helping Sweden to reach the goals in energy policy. Nevertheless, hydropower causes environmental footprint in different ways. In order to implement
Cationic vinylpyridine based molecularly imprinted polymer monoliths were, for the first time, applied to enantiomer separation using capillary electrochromatography. In order to map the synthesis conditions under which superporous monoliths are obtained, capillary columns were prepared by an in situ polymerization technique using varying monomer and porogen compositions. Both electrolyte pH and p
Lipid-binding proteins Sequester amphiphilic molecules in a large internal : cavity occupied by similar to 30 water molecules, some of which are displaced by the ligand. The role; of these internal water molecules in lipid binding and release is not understood. We use magnetic relaxation dispersion (MRD) to directly monitor internal-water dynamics in apo and palmitate-bound rat intestinal fatty ac
This book is particularly concerned with examining the creation of the Öresund region, a process that represents the internationalization and geopolitical changes in the world, where new industrial regions emerge in competition for growth and wealth. The emerging Öresund region is a new type of industrial region – a transnational region that is difficult to analyze in a traditional way, for examp
Purpose - One current trend in burner technology is to obtain high efficiency while keeping low levels of NOx emissions. A swirling flow in combustion ensures a fixed position of a compact flame. Therefore, it is necessary to design efficient swirlers. Flow patterns are simulated for the different swirl devices proposed in this work. Two axial-swirlers are studied: one based on curve-vanes consist
This thesis presents an improved version of the classic relay autotuner. The proposed autotuner uses an asymmetric relay function to better excite the process in the experiment phase. The improved excitation provides the possibility to obtain better models and hence better tuning, without making the autotuner more complicated or time consuming.Some processes demand more accurate modeling and tunin
A study of three different adhesives, silicone, acrylate and polyurethane, intended for adhesive joints in structural timber/glass applications is presented in this paper. Intentionally, adhesives with a wide range of properties were chosen. The adhesive bonds between timber and glass were tested both in tension and in shear with a bond area of 800 mm2. Special fixtures were designed
Popular Abstract in Swedish Mot en sammanhållen och hållbar biomassapolitik: En studie av europeisk biomassa-för-energi-planering Biomassa används för många ändamål. När den används som biobränsle för att producera energi utgör den en förnybar energikälla med många fördelar, bl. a. i form av minskade utsläpp av växthusgaser och en ökad trygghet i energiförsörjningen. Men biomassa är även en råvaCoordination of policies embracing biomass use has been called for in order to speed up progress towards the European Union renewable energy and climate change goals. Policy coordination and coherence is also required if the many complex and diverse issues constraining sustainable bioenergy development are to be addressed. To contribute to meeting such needs this doctoral thesis provides insights
A laboratory study was executed to investigate the effect of surfactants to enhance sorption of polycyclic aromatic hydrocarbon (PAH) contaminants in loess soil. Phenanthrene and naphthalene were chosen as organic contaminant indicators in loess soil modi. fied by the cation surfactant hexadecyltrimethylammonium (HDTMA) bromide. The kinetic behavior of sorption during transport in natural and modi
Utsagor från vittnen är ett väsentligt inslag i en effektiv rättskipning. Hot och våld mot vittnen utgör därför ett stort hinder i det brottsbekämpande ar-betet. Om det allmänna inte kan erbjuda vittnen ett tillräckligt skydd vid så-dana angrepp, finns det risk att vittnen väljer att inte samarbeta med polisen, vilket i sin tur kan få till följd att grova brott förblir ouppklarade. I denna studie Statements by witnesses are an essential element of the efficient administra-tion of justice. The occurrence of serious forms of threats and violence to-wards witnesses and their relatives therefore constitutes a major impediment to the work in combating crime. If the public cannot offer witnesses suffi-cient protection from attacks, there is a risk that they will choose not to co-operate with the
Sammanfattning Uppsatsen visar hur det politiska målet giftfri miljö genomförs när det gäller förorenade områden. Som bakgrund beskrivs dagens föroreningssituation och hur den uppkommit, vilka tekniker som finns för avhjälpande samt vilka riktlinjer som gäller för marken efter saneringen. Sedan redogörs för de olika möjligheter till avhjälpande av föroreningar som finns inom ramen för miljöbalken,Summary This essay points out how the political objective non-toxic environment1 has been implemented regarding contaminated land areas. As a background the contamination situation of today and why it occurred is described as well as different techniques for restoration2 and the guidelines that apply to the land after remediation. The public authorities have in the Environmental Code and the Plan
The management of the mining sector in Sierra Leone is characterised by numerous integrations of government and donor agency policies, resembling that of global development agendas advocating for improvements of governance, transparency, capacity building and revenue generation. We must view the global policies in their local scales in order to substantiate their actual effects. The central argu
Our purpose was to examine the view and perspectives of the residential staff about the disabled individual’s sexuality. Our study was executed in three different group homes. Three questions evolved in our process and quest for insight: How does the residential staff construct the disabled sexuality in a group home? What is the staff´s perception of the disabled responsibility concerning their s
Background: Registry data used to monitor clinical care need to be reliable, and the process for assuring data quality transparent. Here the auditing process of the Swedish quality registry for cardiac disease, SWEDEHEART, is described. Methods: SWEDEHEART audits have been performed at 4 time-points in 2011 to 2018, with data quality audited in the 3 largest subregistries covering acute coronary s
