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DNA fragmentation characteristic of apoptosis and cell loss induced by kainic acid in rabbit retinas

We have examined whether in vivo exposure to the glutamate analogue, kainic acid, induces cell loss through apoptosis and/or through necrosis. The vulnerability of rabbit retinal cells was evaluated by routine histopathology. The DNA fragmentation was examined using an in situ method (TUNEL: TdT-mediated biotin-dUTP nick-end labelling) and agarose gel electrophoresis of extracted retinal DNA. Reti

Religion in post-disaster recovery

Religion is particularly important in times of crises; it is commonly linked to the search for meaning behind disasters and it promotes a social interconnectedness. After a disaster, religious beliefs can give the survivors a sense of control. Rituals and ceremonies have proved to have healing capacities both individually and collectively. The focus of this paper is on religion in the recovery pro

The energy performance of a single-screw compressor for natural gas liquefaction process : Effects of the lubricating oil flow rate

An experimental test system including the oil circulation system and the gas circuit system has been designed and built to explore the effects of the lubricating oil flow rate on the performance of a single-screw compressor, used in a portable natural gas liquefaction process. Outlet pressure, outlet volumetric flow rate, volumetric efficiency, and specific power rate are the parameters for evalua

In situ real-time monitoring techniques for membrane fouling in food, biorefinery and biotechnology industries

Membrane fouling is a constant challenge of membrane processes in separation and purification of organic, biomass originated compounds in food, biorefining and biotechnology industries. It persists due to the complexity and high fouling tendency of the bio-based streams and may result in a decrease of filtration capacity, rejection alteration, reduction of membrane lifetime and increase of operati

The CJEU as an innovator – a new perspective on the development of Internet related case-law

n this paper I will use concepts from innovation theory to analyse the work of the Court of Justice of the European Union in its important role as sole interpreter of EU law. In that regard, I define ‘innovator’ as one that facilitates use of new or existing inventions. Thus innovation is portrayed as a process in which several actors may contribute and where it all starts with an invention (the s

Membrane opportunities in production and water loop of biorefineries based on lignocellulosic biomass

In recent years biorefineries using lignocellulosic biomass such as wood and agricultural residuals as raw material have gained significant interest since they avoid competition with food production. One of the key development areas of these lignocellulosic based biorefinery concepts is the integration low energy and high selective separation processes. Thus, membrane processes either as stand-alo

IP lab measurements on E. coli-sand-mixtures

Aim of the MIRACHL project is the characterisation and monitoring of in-situ remediation of chlorinated hydrocarbon contamination using an interdisciplinary approach. Therefore, geophysical methods, as e.g. DCIP are used to investigate the remediation process.To interpret these geophysical field IP data, lab investigations with different kinds of bacteria are necessary to assess the sensitivity of

The Creation of Transnational Memory Spaces : Professionalization and Commercialization

In the age of globalization, local memories of past violence are often dislocated from their material places as remembrance is transpiring in transnational memory spaces. Historical events and commemorative memory practices increasingly transcend national boundaries and change the way memories of historical violence, atrocity, and genocide are represented in the transnational memoryscape. This art

Protein self-diffusion in crowded solutions

Macromolecular crowding in biological media is an essential factor for cellular function. The interplay of intermolecular interactions at multiple time and length scales governs a fine-tuned system of reaction and transport processes, including particularly protein diffusion as a limiting or driving factor. Using quasielastic neutron backscattering, we probe the protein self-diffusion in crowded a

Cerebral protection by AMPA- and NMDA-receptor antagonists administered after severe insulin-induced hypoglycemia

Excitatory amino acids are implicated in the development of neuronal cell damage following periods of reversible cerebral ischemia or insulin-induced hypoglycemic coma. To explore the importance of glutamate receptor activation in the posthypoglycemic phase, we exposed rats to 20 min of insulin-induced severe hypoglycemia. The rats were treated immediately after the hypoglycemic insult with four r

Impact of storage time prior to cryopreservation on mechanical properties of aortic homografts

Optimal time spans in homograft procurement are still debatable among tissue banks and needs to be further investigated. Cell viability decreases at longer preparation intervals, but the effect on collagen and elastic fibers has not been investigated to the same extent. These fibers are of importance to the homograft elasticity and strength. The objective of this study was to analyze the mechanica

Breaking the patientification process - through co-creation of care, using old arctic survival knowledge

Syfte: Cancerforskning och relaterade innovationsprocesser saknar ofta en viktig komponent; patientdeltagande. Vi nyanalyserar tre studier (a-c) för att undersöka hur teorin Nuets förnöjsamhet kan användas för att förbättra patientens deltagande och psykosociala hälsa.Metod: Vi återanalyserade data från den klassiska grundade teoristudien om Nuets förnöjsamhet, baserad på fyra års observation och

Post-processing removal of non-real characteristic modes via basis function perturbation

For more than 30 years since it was first proposed by Harrington et al., the Theory of Characteristic Mode (TCM) has only been applied to perfect electric conductors (PEC), and more recently lossless dielectric materials. One key challenge in computing the characteristic modes (CMs) of non-PEC materials using the PMCHWT surface integral equation is the presence of internal resonances in the soluti

Fabrication and characterization of aluminum matrix fly ash cenosphere composites using different stir casting routes

Aluminum matrix fly ash (AMFA) cenosphere composites were fabricated using the stir casting technique. The used type of fly ash cenosphere, which accounted for over 60% in all fly ash particles, was in narrow and small size (2-30 μm). During synthesis, effects of several key technological parameters on microstructure and properties were investigated using orthogonal experimental design. The optima

Nine residues in HLA-DQ molecules determine with susceptibility and resistance to type 1 diabetes among young children in Sweden

HLA-DQ molecules account over 50% genetic risk of type 1 diabetes (T1D), but little is known about associated residues. Through next generation targeted sequencing technology and deep learning of DQ residue sequences, the aim was to uncover critical residues and their motifs associated with T1D. Our analysis uncovered (αa1, α44, α157, α196) and (β9, β30, β57, β70, β135) on the HLA-DQ molecule. The

Developing a regional superbus concept - collaboration challenges

The 2014 Swedish National infrastructure plan allocated funds to implement a “Regional Superbus concept”. The concept involves the upgrading a number of existing regional express bus services to make them function as an alternative to investing in regional rail. The Regional superbus concept is an attempt to adapt the BRT planning philosophy to the regional scale and the context of the region it s

Gender equality and local governance : Global norms and local practices

From the global to the local level, gender inequality is the most persistent and entrenched challenge to development. The local level of governance is closest to citizens. Decisions taken at this level have the most direct effect on citizen’s everyday lives, as improvements in living, working and leisure conditions depend on good local governance. This chapter focuses on local government. It attem

Architecture Design of a Memory Subsystem for Massive MIMO Baseband Processing

This brief presents an on-chip memory subsystem for massive multiple-input-multiple-output (MIMO) baseband processing at the base station. In massive MIMO systems, the required memory bandwidth and capacity are orders of magnitude higher than those used in conventional wireless systems, due to the large number of serving antennas. These are further combined with design targets on low access latenc

The role of work-integrated learning in preparing students for a corporate entrepreneurial career

Purpose: In the literature there is limited knowledge about how to prepare students for a corporate entrepreneurial career. The purpose is therefore to develop a framework for understanding the role corporate development projects play in corporate entrepreneurship education, and to examine the potential role of the design of the project. The study defines a corporate development project as a proje