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This work provides new insights into the presence of 239Pu, 240Pu, 241Pu, and 236U in the Southern Hemisphere through the study of peat bog cores from marshlands in Madagascar (19°S). 210Pb, 238Pu and 239+240Pu activities were characterized by alpha spectrometry in previous studies. Here, Pu from alpha-spectrometry discs corresponding to 10 peat-bog cores (85 samples) was reassessed for the aim of

Background: Potent antithrombotic therapy has significantly improved prognosis for patients with acute myocardial infarction (AMI), however, at a price of increased bleeding risk. Chronic gastric infection with Helicobacter pylori (Hp) commonly causes upper gastrointestinal bleeding and is proposed as a risk factor for subsequent bleeding post AMI. The prevalence of active Hp in a current AMI popu

Colorectal cancer (CRC) is the third most common cancer worldwide. Increasing evidence suggests that CRC should be considered a heterogeneous disease, with multiple differences between proximal and distal tumours. The immune system may, depending on the context, promote or inhibit tumour growth, and different immune cell subsets have been found to be associated with impaired or improved prognosis

The major histocompatibility complex class I (MHC-I) has recently been shown not only to present antigens to the immune system but also to mediate transmembrane signaling, resulting in activation, inactivation, or apoptosis. Such signaling has been observed in both normal and malignant cells of the B and T cell lineage. Cross-linking of MHC-I on the pre-B- acute-lymphocytic cell line KM-3 induces

Objective: To update evidence for available therapies in the treatment of hip and knee osteoarthritis (OA) and to examine whether research evidence has changed from 31 January 2006 to 31 January 2009. Methods: A systematic literature search was undertaken using MEDLINE, EMBASE, CINAHL, AMED, Science Citation Index and the Cochrane Library. The quality of studies was assessed. Effect sizes (ESs) an

Popular Abstract in Swedish Syn är avgörande för många djurs överlevnad. En väldigt viktig del av ögat är linsen då ljuset fokuseras genom den. I denna studie har jag undersökt hur fisklinser fokuserar ljus. Valet av fiskar som försöksdjur berodde på att de är lätta att skaffa och deras linser är klotformade, vilket underlättar beräkningen av strålgången och linsens optiska egenskaper. Hos fiskar Vision is an important source of information for many animals. The lens plays a central role in the visual pathway and hence the ecology of these animals. Fish have spherically shaped crystalline lenses that contain a gradient of refractive index. Like all refracting elements, lens performance depends on the wavelength of the refracted light. This wavelength dependent focusing leads to chromatic a

Acoustic fatigue can occur in structural elements of an aircraft exposed to very high sound pressures. To deal with acoustic fatigue, mainly empirical methods have been applied and often late in the design phase. Current design guidelines have several limitations. First, they do not say anything about the load intensities. The load levels can be determined either experimentally or numerically. Exp

Mineralogical and geochemical studies of the non-marine Permian–Triassic (P–Tr) boundary across two stratigraphically wellconstrained sections (Commando Drift Dam and Wapadsberg, Eastern Cape Province) in the southern Karoo Basin, South Africa, have been undertaken to provide further input on the cause of this mass extinction event, and so has a sedimentological and geochemical evaluation of a thi

Purpose: To determine progression factors at the end of the Early Manifest Glaucoma Trial (EMGT) based on all EMGT patients and evaluate separately patients with higher and lower baseline intraocular pressure (IOP; median split). Design: Cohort of clinical trial participants. Participants: Patients with early open-angle glaucoma randomized to argon laser trabeculoplasty plus betaxolol (n = 129) or

Fractions rich in indigestible carbohydrates, such as fructan and arabinoxylan, are obtained as by-products when ethanol, starch, and gluten are produced from wheat flour. Today, these fractions are used as animal feed. However, these components may have positive physiological effects in humans. In this study, the content of indigestible carbohydrates in distillers' grains and process streams from

Importance: Clonal hematopoiesis of indeterminate potential (CHIP) may contribute to the risk of atrial fibrillation (AF) through its association with inflammation and cardiac remodeling. Objective: To determine whether CHIP was associated with AF, inflammatory and cardiac biomarkers, and cardiac structural changes. Design, Setting, and Participants: This was a population-based, prospective cohort

BACKGROUND: The use of nitrous oxide (N2O) during hemodilution has been questioned. Nitrous oxide reduces the inspired oxygen fraction (F1O2), depresses myocardial function and may reduce cardiac output (CO) and systemic oxygen delivery (DO2SY). The aim of this study was to evaluate the importance of the effects of nitrous oxide on systemic and myocardial circulation and oxygenation during extreme

An evaluative neutralisation process, whereby questionnaire items are phrased to be less evaluative, was used to create a new less socially desirable version of the social dominance orientation scale (SDO7). The main goal is to counteract the persistent floor effect which has affected the scale since its inception. The rationale behind the suggested correction is rooted with the problem of social

'Identity' is a frequently used concept within the field of European studies, which has resulted in a myriad of different perspectives on what its meaning entails. As such, the meaning of identity is often claimed to be ambiguous, which causes problems for methodology related issues. This thesis suggests that the field of European Studies as a research area has to adjust its approach to th

Sammanfattning Uppsatsens titel: Redovisningsskandaler och medias rapportering kring revisorsrollen - En dokumentstudie av fallet Fermenta. Seminariedatum: 28 maj, 2012. Ämne/kurs: Examensarbete på Civilekonomprogrammet, 30 HP, Magisternivå. Författare: Olof Ekman Ovenholm. Handledare: Anne Loft och Niklas Sandell. Fem nyckelord: redovisningsskandaler, Fermenta, Refaat El-Sayed, affärspress,Summary Title: Accounting scandals and the media's reporting concerning the role of the auditor - A document study of the Fermenta case. Seminar date: May 28th, 2012. Course: Master thesis in business administration, 30 University Credit Points (30 ECTS). Author: Olof Ekman Ovenholm. Advisor/s: Anne Loft and Niklas Sandell. Five key words: accounting scandals, Fermenta, Refaat El-Sayed,

There is an urgent need for accurate and validated methods to measure plasma phosphorylated tau (p-Tau) biomarkers in Alzheimer’s disease (AD). In this study, we compared the performance of new commercially available plasma p-Tau217 assay developed by ALZpath to other established p-Tau assays in an autopsy-confirmed sample. We included 72 participants from the Arizona Study of Aging and Neurodegen

Background: Disorders affecting the nervous system are diverse and include neurodevelopmental disorders, late-life neurodegeneration, and newly emergent conditions, such as cognitive impairment following COVID-19. Previous publications from the Global Burden of Disease, Injuries, and Risk Factor Study estimated the burden of 15 neurological conditions in 2015 and 2016, but these analyses did not i

Before performing 177Lu-DOTATATE therapy for neuroendocrine tumors, somatostatin receptor (SSTR) PET imaging is currently used to confirm sufficient tumor SSTR expression, but it also has potential to be used to personalize treatment by predicting absorbed doses to critical organs. This study aims to validate the predictive capability of SSTR PET in anticipating renal absorbed dose in the first cy

Evidence from neuropathological cohorts indicates that a CSF α-synuclein (α-syn) seed amplification assay (SAA) might provide quantitative kinetic parameters correlating with α-syn pathology burden in patients with Lewy body disease (LBD). Studies are needed to assess their longitudinal trend during the presymptomatic and clinical disease phases and their correlation with measures of disease progr