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Re-interpreting rationalities of risky migration : Syrian refugees´ sea journeys to Europe Dance between wisdom and despair

The thesis explores the migration experiences of Syrian refugees who arrived in Sweden and Denmark by crossing the Mediterranean Sea in small, precarious boats. It aims to illuminate how these refugees managed the risks they faced during their journey to Europe and the meanings they associated with these risks. The research focuses on the socio-cultural and individual contexts within which risk is

Lasmiditan and 5-Hydroxytryptamine in the rat trigeminal system; expression, release and interactions with 5-HT1 receptors

Background: 5-Hydroxytryptamine (5-HT) receptors 1B, 1D and 1F have key roles in migraine pharmacotherapy. Selective agonists targeting these receptors, such as triptans and ditans, are effective in aborting acute migraine attacks and inhibit the in vivo release of calcitonin gene-related peptide (CGRP) in human and animal models. The study aimed to examine the localization, genetic expression and

Zero and Multi-Dimensional Modeling of Internal Combustion Engines with respect to Ion Current and Soot Formation

The work presented in this thesis can be divided into the three following fields of investigation: First of all the ionization model developed in this thesis is meant to simulate the thermal ionization process or the so-called second peak. Equilibrium assumptions have been adopted for the modeling of the thermal ionization, in which Saha’s equation was derived for singly ionized molecules. The inv

Patterns of opportunity spaces and agency across regional contexts : Conditions and drivers for change

Non-metropolitan regions are considered more exposed to external shocks than their metropolitan counterparts, while having lower capacities to change. However, there is considerable variation among non-metropolitan regions. We argue that this variation can be captured theoretically by modelling the dynamic interplay between perceived and real opportunity spaces and agency. We empirically analyse r

Geolocator tagging of east Siberian Bluethroats

The Bluethroat subspecies Cyanecula svecica svecia occurs throughout the northern Palearctic. European C. s. svecia has been shown to follow a route west of the Himalaya to winter quarters in southern Asia. Out of 30 Bluethroats tagged with geolocators in eastern Siberia, we obtained one track suggesting that it migrated east of the Himalaya to a wintering area located in Myanmar. The different ro

A Simple End-to-End Computer-Aided Detection Pipeline for Trained Deep Learning Models

Recently, there has been a significant rise in research and development focused on deep learning (DL) models within healthcare. This trend arises from the availability of extensive medical imaging data and notable advances in graphics processing unit (GPU) computational capabilities. Trained DL models show promise in supporting clinicians with tasks like image segmentation and classification. Howe

Diclofenac for acute postoperative pain in children

Background: Many children undergo various surgeries, which often lead to acute postoperative pain. This pain influences recovery and quality of life. Non-steroidal anti-inflammatory drugs (NSAIDs), specifically cyclo-oxygenase (COX) inhibitors such as diclofenac, can be used to treat pain and reduce inflammation. There is uncertainty regarding diclofenac's benefits and harms compared to placebo or

Tidal Zones : Filming Between Life and Images

Informed by queer life practices, theories, and affinities, this documented artistic research project (doctoral thesis) draws from new materialist and post-humanist discourse in order to reconsider what role visual media play in the historical need to separate the human and the environmental. It asks, how do we challenge prevailing perceptions of film and photography as inexorably linked to ideas

Silence, Order, Obedience and Discipline : The educational discourse of the Argentinean Military Regime (1976-1983)

This dissertation deals with the educational discourse of the military government in Argentina during the years 1976-1983. In March 1976, the army assumed power through a coup d´état. The intervention was carried out in the name of Order, i. e. to save the country from the crisis in which it was immersed. Through the Proceso de Reorganization Nacional they attempted to restore order and discipline

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The concept “Broken Technologies” is related to the question: “Which is the benefit of humanity studies?” Of course the question is rhetorical because, how could this question be answered if the benefit was not obvious? Any answer supposes that we understand what we are asking for and the study of “what we mean” is one of the axes of the epistemology of the humanities. Anyway, we can also put the

Quantitative assessment of the antiviral potencies of 21 shRNA vectors targeting conserved, including structured, hepatitis B virus sites

Background & Aims: RNA interference (RNAi) may offer new treatment options for chronic hepatitis B. Replicating via an RNA intermediate, hepatitis B virus (HBV) is known to be principally vulnerable to RNAi. However, beyond delivery, the relevant issues of potential off-target effects, target site conservation in circulating HBV strains, and efficacy of RNAi itself have not systematically been

Lack of Accuracy for the Proposed 'Dubois Criteria' in Alzheimer's Disease: A Validation Study from the Swedish Brain Power Initiative

Background/Aims: Our purpose was to investigate whether the new research criteria for Alzheimer's disease proposed in 2007 by Dubois et al. are valid in a naturalistic memory clinic sample. Method: Retrospective diagnostic analyses were carried out to compare the traditional diagnostic criteria for dementia with the new criteria suggested by Dubois et al. No patient had gone through all procedures

Deregulation and editing of microRNAs in metastatic prostate cancer

Prostate cancer bone metastasis is still not fully understood, and increased knowledge could aid in the development of better treatment options for patients in the future. This thesis focuses on microRNAs (miRNAs), which modulate gene expression in healthy and tumour cells. Using cell culture, animal and patient studies, we investigated the biological role of microRNA-96 (miR-96) and microRNA-379

Central Limit Theorem for Exponentially Quasi-local Statistics of Spin Models on Cayley Graphs

Central limit theorems for linear statistics of lattice random fields (including spin models) are usually proven under suitable mixing conditions or quasi-associativity. Many interesting examples of spin models do not satisfy mixing conditions, and on the other hand, it does not seem easy to show central limit theorem for local statistics via quasi-associativity. In this work, we prove general cen

Surviving in the Ashes : A Preliminary Assessment of Socio-Ecological Responses to a "Super-Eruption" in Foraging Southwest Japan (7,300 cal BP)

Major volcanic eruptions are one of the most devastating and unpredictable events for all societies past and present. Althoughmajor progress has been made by archaeologists in understanding volcanic impacts on past societies, almost all this work hasfocused on urban or settled agricultural societies. In contrast, there is a major gap in knowledge about how forager communitieswere able to respond a

Telomeres in ecology and evolution: Hypotheses and connections between telomere length, infections and life history trade-offs

Studying life history strategies is crucial for understanding the diversity among organisms. The trade-offs in traits related to survival, self-maintenance and reproduction play an important role in the variation of life histories and can be adjusted in response to environmental and physiological factors. Telomeres, which are repetitive DNA sequences found at the ends of chromosomes, can serve as

Hinder för entreprenad enligt AB 04 - Om entreprenörens rätt till tidsförlängning och skadestånd vid hinder som beror på beställaren eller något förhållande på dennes sida

Entreprenader löper stor risk att utsättas för hinder som medför att den avta-lade kontraktstiden inte kan hållas. Det kan exempelvis handla om extrema väderförhållanden som försvårar arbetet, eller arbetsområden som inte är tillgängliga för entreprenören på grund av en sidoentreprenör. Den här uppsatsen syftar till att utreda frågan om när ett hinder kan anses bero på beställaren, eller något förDuring the course of construction, there is a high risk of events that cause delays for the contractor. These events can for example con¬sist of extreme weather conditions that are obstructing the construction works, or the work area being occupied by sub-contractors. This thesis aims to investigate un¬der what conditions the contractor can be given extension of time and/or compensation for prolon

Produktutveckling av kontrollenhet

This master thesis was performed at the company Radinn AB in Lund, Sweden. The company develops and will in the coming year start to sell their first product which is an electric powered wakeboard. As the company not yet has started selling this board and it is a newly started company some information will be held as a secret to the reader. The wakeboard is in need of a control to set the throttle