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Investigations of the kinetics and mechanism of reduction of a carboplatin pt(IV) prodrug by the major small-molecule reductants in human plasma

The development of Pt(IV) anticancer prodrugs to overcome the detrimental side effects of Pt(II)-based anticancer drugs is of current interest. The kinetics and reaction mechanisms of the reductive activation of the carboplatin Pt(IV) prodrug cis,trans-[Pt(cbdca)(NH3)2Cl2] (cbdca = cyclobutane-1,1-dicarboxylate) by the major small-molecule reductants in human plasma were analyzed in this work. The

Performing Instagram photography and the disciplining gaze

This paper approach participation in visual promotional strategies as a novel form of public performance. The paper examines the social rules and conventions of photography practices on visual social media platforms in a qualitative study of how 30 participants in so-called Instagram takeovers make sense of and perform photography as an embodied visual practice situated in time and space.A dramatu

Pancreatic lipolytic enzymes in human duodenal contents. Radioimmunoassay compared wih panreatic lipolytic enzyme activity

The total pancreatic lipolytic capacity was determined in duodenal contents in healthy humans 10-120 min after a liquid test meal, by estimating the amount of pancreatic lipase, colipase, carboxyl ester lipase, and phospholipase A2 by means of radioimmunoassays and enzymatic assays. The molar concentrations of the different proteins were of the same order of magnitude. The relative specific activi

Verification of sheet metal forming simulation of advanced thin plate parts using a first order friction model

There is today a need of better prediction of part geometry regarding industrial products by simulations. There is a need for better prediction of material inflow, stresses and strains and final geometry. One way to solve this could be by using a more advanced friction model. Today a zero order friction model (Coulomb friction) is normally used. By using a friction model of higher order the fricti

Mutation testing optimisations using the Clang front-end

Mutation testing is the state-of-the-art technique for assessing the fault detection capacity of a test suite. Unfortunately, a full mutation analysis is often prohibitively expensive. The CppCheck project for instance, demands a build time of 5.8 min and a test execution time of 17 s on our desktop computer. An unoptimised mutation analysis, for 55,000 generated mutants took 11.8 days in total, o

Frequency Generation and Baseband Filters for mm-Wave 5G and 6G Transceivers

In order to keep up with the constant demand for higher data rates, the fifth generation of mobile communication (5G) introduced the use of mm-wave carrier frequencies from 24 to 71 GHz. Plenty of new frequency spectrum then became available, which has allowed for channel bandwidths of several hundreds of MHz. 6G is projected to continue this trend with even higher carrier frequencies and wider ba

Nature by numbers: an evaluation of how DEFRA’s Biodiversity Metric 3.0 can or cannot capture rewilding outcomes

The United Kingdom’s response to the pressing biodiversity decline in England includes the Biodiversity Net Gain (BNG) policy and is operationalised through DEFRA’s Biodiversity Metric, which quantifies biodiversity into ‘biodiversity units’. This thesis evaluates how effectively the metric reflects real biodiversity outcomes at the rewilded Knepp Estate in West Sussex. Using 2005 as a baseline an

0a5adda4a3707bbe248b79c0a9d20a53880a28a2 BIOR69 2024 kursanalys

Statistik 10p ekologi BIO 580 Helsingborg HT 2004 COURSE ANALYSIS Date 2024-11-28 Main Teacher: Stefan Andersson Number of students: 36 Number of answers: 21 Grades: 5 pass (G) 31 pass with distinction (VG) Department of Biology Education – Bachelor’s and Master’s level Population and community ecology, BIOR69, autumn 2024 Summary of the digital course evaluation Mean score across students (maximu

https://www.lunduniversity.lu.se/sites/www.lunduniversity.lu.se/files/0a5adda4a3707bbe248b79c0a9d20a53880a28a2_BIOR69_2024_kursanalys_.pdf - 2026-05-06

Erfarenheter av vindkraftsetablering: Förankring, acceptans och motstånd.

Many politicians and researchers perceive wind power as an important part of future energy supply, nationally and globally. However, it has turned out to be problematic to expand wind power in the pace necessary to meet the national and international goals about wind power expansion. A significant challenge concerns the social and policy-related processes surrounding the establishment of wind powe

Enhanced Biological Phosphorus Removal -Processes, Competing Substances and Tools for Operation of Wastewater Treatment Plants

Popular Abstract in Swedish Avloppsvatten renas från fosfor för att minimera utsläppet till sjöar och hav. Näringsämnena fosfor och kväve bidrar till övergödningen i våra vatten och kan reduceras kraftigt på avloppsreningsverken. Fosforavskiljning går huvudsakligen ut på att få löst fosfat att hamna i en fast fas ? slammet, för att sedan kunna avskilja det från det renade vattnet. Bakterier som vThe idea of phosphorus removal at wastewater treatment plants is to transfer dissolved phosphorus into a solid phase. Together with the rest of the produced sludge it is then removed from the water, resulting in a decreased concentration of phosphorus in the effluent and the prevention of the eutrophication in the recipient. Phosphorus can either be stored biologically, with enhanced biological p

Denitrification at low temperatures using a suspended carrier biofilm process

The denitrification process was studied in a stirred lab-scale suspended carrier biofilm reactor at low temperatures (3–20°C). The reactor was filled to 50% with Kaldnes K1 carriers. The denitrification rate showed only a rather weak dependence on the temperature, the rate at 3°C being approximately 55% of that at 15°C. The maximum denitrification rate obtained at 15°C was 2.7 g NOx−-N m−2 carrier

Med främmande bagage : Tankar och erfarenheter hos unga människor med ursprung i en annan kultur eller Det postmoderna främlingskapet

Popular Abstract in Swedish Allt fler ungdomar i vårt land, liksom i många andra länder, lever i vardagen med mer än en kultur. En femtedel av eleverna i den svenska skolan är antingen själva födda i ett annat land eller har minst en förälder med utländsk bakgrund. För många av dessa barn och ungdomar har därför inte samhällets dominerande kultur funnits med från början av deras liv. Bekantskapen The present study is based on interviews with 22 youth and young adults. The perspective is phenomenological, since my aim has been to analyse and describe the everyday world as it presents itself to these young people. A process begins in the encounter with the majority culture and the emphasis is on how they think about events and experiences along the road to a more complex life-world. The proc

A comparison of digital morphometry and clinical measurements of ears.

Abstract Clinical measurements are necessary in many routine follow-ups and scientific evaluations, but the accuracy of these measurements is seldom challenged. The size of the reconstructed ear is one important parameter in the follow-up regarding patients operated on due to microtia. With the introduction of digital morphometry one was obliged to evaluate its accuracy in comparison to its analog

Using simulation to analyse the impact of software requirement volatility on project performance

During the last decade, software process simulation has been used to address a variety of management issues and questions. These include: understanding; training and learning; planning; control and operational management; strategic management; process improvement and technology adoption. This paper presents a simulation model that was developed to demonstrate the impact of unstable software requir

The origin of tail-like structures around protoplanetary disks

Aims. We study the origin of tail-like structures recently detected around the disk of SU Aurigae and several FU Orionis-type stars. Methods. Dynamic protostellar disks featuring ejections of gaseous clumps and quiescent protoplanetary disks experiencing a close encounter with an intruder star were modeled using the numerical hydrodynamics code FEOSAD. Both the gas and dust dynamics were taken int

Pankreascancer kan metastasera tidigt : Tumörbiologi tycks viktigare än tumörstorlek

Pancreatic cancers are associated with poor survival and only some 10 per cent are resectable, but even in this subgroup recurrence is very frequent. The traditional view of sequential development of pancreatic cancer has been challenged by novel molecular biological findings, where the tumor quite rapidly might turn metastatic. In about 60 000 patients with diagnosed pancreatic cancer the associa