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Elicitation and management of user requirements in market-driven software development

Market-driven software development companies experience challenges in requirements management that many traditional requirements engineering methods and techniques do not acknowledge. Large markets, limited contact with end users, and strong competition forces the market-driven software development company to constantly invent new, selling requirements, frequently release new versions with an acco

Mammalian Molecular Systematics with Emphasis on the Insectivore Order Lipotyphla

Insectivore classification has been one of the most controversial problems in mammalian systematics. Evolutionary relationships among the six extant families, Talpidae (moles), Soricidae (shrews), Erinaceidae (hedgehogs), Tenrecidae (tenrecs), Chryosochloridae (golden moles), and Solenodontidae (solenodons), have remained uncertain based on morphological data. Animals classified within the order L

Zero and Multi-Dimensional Modeling of Internal Combustion Engines with respect to Ion Current and Soot Formation

The work presented in this thesis can be divided into the three following fields of investigation: First of all the ionization model developed in this thesis is meant to simulate the thermal ionization process or the so-called second peak. Equilibrium assumptions have been adopted for the modeling of the thermal ionization, in which Saha’s equation was derived for singly ionized molecules. The inv

Adaptive plasticity during the development of colour vision

Colour vision greatly enhances the discriminatory and cognitive capabilities of visual systems and is found in a great majority of vertebrates and many invertebrates. However, colour coding visual systems are confronted with the fact that the external stimuli are ambiguous because they are subject to constant variations of luminance and spectral composition. Furthermore, the transmittance of the o

Solar Longitude Distribution of High-energy Proton Flares : Fluences and Spectra

The distribution of the longitudes of solar flares associated with the high-energy proton events called ground level events (GLEs) can be approximated by a Gaussian with a peak at ∼W60, with a full range from ∼E90 to ∼W150. The longitudes of flares associated with the top third (24 of 72) of GLEs in terms of their >430 MeV fluences (F 430) are primarily distributed over E20-W100 with a skew toward

Clickable decellularized extracellular matrix as a new tool for building hybrid-hydrogels to model chronic fibrotic diseases in vitro

Fibrotic disorders account for over one third of mortalities worldwide. Despite great efforts to study the cellular and molecular processes underlying fibrosis, there are currently few effective therapies. Dual-stage polymerization reactions are an innovative tool for recreating heterogeneous increases in extracellular matrix (ECM) modulus, a hallmark of fibrotic diseases in vivo. Here, we present

Seasonal variability of stable carbon isotopes (δ13CDIC) in the Skagerrak and the Baltic Sea : Distinguishing between mixing and biological productivity

We documented the annual cycle of the carbon isotopic composition of dissolved inorganic carbon (δ13CDIC) in the water columns of the Skagerrak and Baltic Sea to obtain an increased understanding of the processes involved controlling the carbon isotopic distribution in shelf seas. The lowest δ13CDIC values (-4.9‰) were found in the low-oxygen, brackish Baltic bottom water whereas the highest value

Measurements of top-quark pair to Z-boson cross-section ratios at √s=13 , 8, 7 TeV with the ATLAS detector

Ratios of top-quark pair to Z-boson cross sections measured from proton-proton collisions at the LHC centre-of-mass energies of s=13 TeV, 8 TeV, and 7 TeV are presented by the ATLAS Collaboration. Single ratios, at a given s for the two processes and at different s for each process, as well as double ratios of the two processes at different s, are evaluated. The ratios are constructed using previo

Opening the door to social equity : local and participatory approaches to transportation planning in Montreal

Purpose: Transportation systems play a key role in providing individuals with a diversity of means to access their desired destinations and have significant impacts on their quality of life. The social perspective of mobility is, however, marginalized in the current model of transportation planning and significant changes are called for. This study aims to identify the barriers and opportunities o

Techno-economic evaluation of biogas upgrading using ionic liquids in comparison with industrially used technology in Scandinavian anaerobic digestion plants

The process of biogas upgrading with ionic liquids, i.e. pure 1-butyl-3-methylimidazolium bis(trifluoro-methylsulfonyl)imide ([bmim][Tf2N]), aqueous choline chloride/urea (ChCl/Urea), and aqueous 1-allyl-3-methyl imidazole formate ([Amim][HCOO]), was simulated in Aspen Plus and compared with the conventional water scrubbing upgrading technique. The comparisons of the performances on the amount of

Ultra-low Voltage Embedded Memories – Design Aspects and a Biomedical Use-case

As the Internet of Things (IoT) era emerges the need for ultra-low power (ULP) devices is becoming more eminent. A research-proven approach to achieve ULP consumption is to aggressively lower the supply voltage (VDD) below or in the vicinity of the transistor threshold voltage (Vth) and operate the transistors in the subthreshold (sub-Vth) region. Operating below or near the threshold voltage, i.eAs the Internet of Things (IoT) era emerges the need for ultra-low power (ULP) devices is becoming more eminent. A research-proven approach to achieve ULP consumption is to aggressively lower the supply voltage (VDD) below or in the vicinity of the transistor threshold voltage (Vth) and operate the transistors in the subthreshold (sub-Vth) region. Operating below or near the threshold voltage, i.e

Diffuse traumatic axonal injury in mice induces complex behavioural alterations that are normalized by neutralization of interleukin-1β

Widespread traumatic axonal injury (TAI) results in brain network dysfunction, which commonly leads to persisting cognitive and behavioural impairments following traumatic brain injury (TBI). TBI induces a complex neuroinflammatory response, frequently located at sites of axonal pathology. The role of the pro-inflammatory cytokine interleukin (IL)-1β has not been established in TAI. An IL-1β-neutr

Short and long-term postural learning to withstand galvanic vestibular perturbations.

We investigated changes of postural responses to repeated bipolar galvanic vestibular stimulation on 5 consecutive days and once again after 3 months. Subjects consisted of 21 healthy volunteers. Except for the first day did the induced torque variance in response to galvanic vestibular stimulation not decrease {within} each test session, but there was a major reduction {from day to day} (p< 0.001

Benzodiazepine prescribing patterns in a high-prescribing Scandinavian community

Sales statistics indicate large variations in benzodiazepine consumption between the Scandinavian countries: the current difference between Denmark (highest) and Sweden (lowest) is almost two-fold. There are also large within-country variations: e.g. benzodiazepine sales in the Swedish city of Helsingborg, which is close to Denmark, were at the average Danish level and were the highest in Sweden.

Surviving in the Ashes : A Preliminary Assessment of Socio-Ecological Responses to a "Super-Eruption" in Foraging Southwest Japan (7,300 cal BP)

Major volcanic eruptions are one of the most devastating and unpredictable events for all societies past and present. Althoughmajor progress has been made by archaeologists in understanding volcanic impacts on past societies, almost all this work hasfocused on urban or settled agricultural societies. In contrast, there is a major gap in knowledge about how forager communitieswere able to respond a

Gravitoviscous protoplanetary disks with a dust component : II. Spatial distribution and growth of dust in a clumpy disk

Aims. Spatial distribution and growth of dust in a clumpy protoplanetary disk subject to vigorous gravitational instability and fragmentation is studied numerically with sub-au resolution using the FEOSAD code. Methods. Hydrodynamics equations describing the evolution of self-gravitating and viscous protoplanetary disks in the thin-disk limit were modified to include a dust component consisting of

Central Limit Theorem for Exponentially Quasi-local Statistics of Spin Models on Cayley Graphs

Central limit theorems for linear statistics of lattice random fields (including spin models) are usually proven under suitable mixing conditions or quasi-associativity. Many interesting examples of spin models do not satisfy mixing conditions, and on the other hand, it does not seem easy to show central limit theorem for local statistics via quasi-associativity. In this work, we prove general cen

The influence of mercury contact angle, surface tension, and retraction mechanism on the interpretation of mercury porosimetry data

The use of a semi-empirical alternative to the standard Washburn equation for the interpretation of raw mercury porosimetry data has been advocated. The alternative expression takes account of variations in both mercury contact angle and surface tension with pore size, for both advancing and retreating mercury meniscii. The semi-empirical equation presented was ultimately derived from electron mic

Performance And Participation : Music Education Practices In Musicking With Young People With Physical Impairments : ISME 2014 World Conference on Music Education Porto Alegre, Brazil, 20-25 July 2014

This presentation highlights results from a research study of ‘Music Week’; a one-week Swedish music project. The aim of the ‘Music Week’ project was to enable young people with physical impairments to take part in musical activities. Digitally-based musical settings were used in order to provide tools for performing and creating music. The main purpose of the present research study was to explore

LL-37-induced human osteoblast cytotoxicity and permeability occurs independently of cellular LL-37 uptake through clathrin-mediated endocytosis

The host defense peptide LL-37 is cytotoxic for bacteria but it has also been reported to reduce host cell viability through an intracellular mechanism. LL-37-evoked cytotoxicity may be involved in the loss of bone tissue in periodontitis which is an inflammatory disease characterized by high concentrations of LL-37 observed locally in the periodontal tissue at the inflammation process. Here, we s