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OBJECTIVES: the purpose of this study was to assess the predictive accuracy of conventional cardiovascular risk factors for incident heart failure and atrial fibrillation, and the added benefit of multiple biomarkers reflecting diverse pathophysiological pathways. BACKGROUND: heart failure and atrial fibrillation are interrelated cardiac diseases associated with substantial morbidity and mortality

The purpose of this study was to investigate the early alterations of retinal function, assessed with electrophysiology, in newly onset type 2 diabetes patients without vascular retinopathy. Seventeen patients with newly diagnosed type 2 diabetes (duration 7 ± 3 months), without any vascular retinopathy in fundus photographs, were examined with full-field electroretinogram (ERG) and multifocal ERG

Popular Abstract in Swedish Denna avhandling behandlar två ämnen inom trådlös kommunikation: interferens mellan frekvenshoppande (FH) nätverk och fleranvändardiversitet. I arbetet på FH nätverk undersöks ett system där frekvenshopp används för att möjliggöra samtidig tillgång till kanalen för multipla okoordinerade nätverk. Detta åstadkoms genom att frekvenshoppen sker varje gång ett ny paket skaThis thesis deals with two topics in wireless communications: interference between frequency-hopping (FH) networks, and multiuser diversity. The work on FH treats a system where FH is used to provide simultaneous access to the channel for multiple uncoordinated wireless networks. This is achieved by performing frequency hops on a packet-by-packet basis, and letting the sequence of hopping frequen

Introduction Many kinds of footwear are used for various purposes in the workplace in Japan. Careful selection of footwear is needed to protect workers from coldness and to keep the performance of workers in cold workplace where employees have to work under -20℃. On the other hand, safety boots with high heat conductivity from foot to outside are needed for the workers in hot environments. But the

This study investigates grammatical development in foreign and second language learners of Swedish. The hypothesis is that the hierarchy of processability predicted by Processability Theory (Pienemann 1998) guides both written and spoken learner production. The data was collected from 9 foreign language learners studying Swedish at Melbourne University and 11 second language learners studying Swed

The conformational entropy of proteins can make significant contributions to the free energy of ligand binding. NMR spin relaxation enables site-specific investigation of conformational entropy, via order parameters that parameterize local reorientational fluctuations of rank-2 tensors. Here we have probed the conformational entropy of lactose binding to the carbohydrate recognition domain of gale

A peptide derived from the N-terminus of the unprocessed bovine prion protein (bPrPp), incorporating the hydrophobic signal sequence (residues 1-24) and a basic domain (KKRPKP, residues 25-30), internalizes into mammalian cells, even when coupled to a sizeable cargo, and therefore functions as a cell-penetrating peptide (CPP). Confocal microscopy and co-localization studies indicate that the inter

Background: Low-level processing and normalization of microarray data are most important steps in microarray analysis, which have profound impact on downstream analysis. Multiple methods have been suggested to date, but it is not clear which is the best. It is therefore important to further study the different normalization methods in detail and the nature of microarray data in general. Results: A

We performed simulations of future biophysical vegetation-climate feedbacks with a regional Earth System Model, RCA-GUESS, interactively coupling a regional climate model and a process-based model of vegetation dynamics and biogeochemistry. Simulated variations in leaf area index and in the relative coverage of evergreen forest, deciduous forest, and open land vegetation in response to simulated c

This textbook in structural mechanics is based on the methodology of the finite element method. The understanding of basic elements of structural mechanics - springs, bars, beams and foundations - is gradually built up in one, two and three dimensions. Using these elements it is demonstrated how complex load-bearing structures can be modelled and analysed. Methods for linear as well as geometric a

Large software organizations with a product line development approach face many challenges regarding testing. Test managers need to make tradeoffs along three dimensions of repeated testing (abstraction level, time and product space) and consider a range of goals and constraints. In order to keep pace with the decreased development time for new products, which is enabled by the systematic reuse, s

OBJECTIVE: To study intra-aneurysm sac pressure and subsequent abdominal aortic aneurysm (AAA) diameter changes in patients without endoleaks that remain unchanged in AAA diameter more than 1 year after endovascular aneurysm repair (EVAR). METHODS: A total of 23 patients underwent direct intra-aneurysm sac pressure (DISP) measurements 16 months (IQR: 14-35 months) after EVAR. Tip-pressure sensors

Tropical biodiversity is threatened by the expansion of oil-palm plantations. Reduced-impact farming systems such as agroforests, have been proposed to increase biodiversity and ecosystem functioning. In regions where oil-palm plantations already dominate the landscape, this increase can only be achieved through systematic ecological restoration. However, our knowledge about the underlying ecologi

IMPORTANCE Fluid overload occurring as a consequence of overly aggressive fluid resuscitation may adversely affect outcome in hemodynamically unstable critically ill patients. Therefore, following the initial fluid resuscitation, it is important to identify which patients will benefit from further fluid administration. OBJECTIVE To identify predictors of fluid responsiveness in hemodynamically uns

We report on the study of fast-neutron background for the BIFROST spectrometer at ESS. We investigate the effect of background radiation induced by the interaction of fast neutrons from the source with the material of the neutron guide and devise a reasonable fast, thermal/cold neutron shielding solution for the current guide geometry using McStas and MCNPX. We investigate the effectiveness of the

Retinitis pigmentosa is a group of inherited retinal degenerative diseases characterized by the loss of photoreceptors and vision for which no effective treatment is available. Several animal models of retinitis pigmentosa are used to elucidate its pathogenesis and to devise therapies. The retinal degeneration (rd1) mouse is one such animal model in which rod-specific phosphodiesterase (PDE) is in