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Complement C2 deficiency (C2D) is associated with immunological diseases and increased susceptibility to invasive infections caused by encapsulated bacteria such as Neisseria menigitidis. In this study we evaluate the immunogenicity of vaccination against N. menigitidis in C2D. C2D patients (n=22) and controls (n=52) were given a tetravalent meningococcal polysaccharide vaccine. Serum bactericidal

Objective. Antileukoproteinase (ALP) is a physiologic inhibitor of granulocytic serine proteases. The present study was undertaken to investigate its therapeutic benefit in an antibody-transfer model of erosive polyarthritis and to elucidate its potential to interfere with immune complex-dependent inflammatory pathways. Methods. Arthritis development was induced in male (BALB/c x B10.Q)F-1 mice by

Transplantation of allogeneic embryonic neural tissue is a potential treatment for patients with Parkinson's and Huntington's diseases. The supply of human donor tissue is limited, and alternatives such as the use of animal (e.g., porcine) donor tissue are currently being evaluated. Before porcine grafts can be used clinically, strategies to prevent neural xenograft rejection must be developed. Kn

Of 30 bacterial species tested 18 stimulated DNA synthesis in human blood lymphocytes. The maximum response was after 3-4 days of culture suggesting a mitogenic effect. This was confirmed by the induction of polyclonal antibody production shown by a plaque assay. Most bacterial species increased the DNA synthesis in B-enriched lymphocytes and unseparated lymphocytes but had negligible activity on

Tissue factor pathway inhibitor-2 (TFPI-2) has previously been characterized as an endogenous anticoagulant. TFPI-2 is expressed in the vast majority of cells, mainly secreted into the extracellular matrix. Recently we reported that EDC34, a C-terminal peptide derived from TFPI-2, exerts a broad antimicrobial activity. In the present study, we describe a previously unknown antimicrobial mode of ac

Background and aimsData exploring normal values of different ventricular–arterial coupling (VAC) parameters and their association with anthropometric and cardiovascular (CV) factors are scarce. We aim to report values of two different methods of VAC assessment according to age and sex and explore their association with CV factors within a large population-based cohort of middle-aged individuals.Me

Small synthetic ligands for protein purification have become increasingly interesting with the growing need for cheap chromatographic materials for protein purification and especially for the purification of monoclonal antibodies (mAbs). Today, Protein A-based chromatographic resins are the most commonly used capture step in mAb down stream processing; however, the use of Protein A chromatography

Hu11B6 is a monoclonal antibody that internalizes in cells expressing androgen receptor (AR)-regulated prostate-specific enzyme human kallikrein-related peptidase 2 (hK2; KLK2). In multiple rodent models, Actinium-225-labeled hu11B6-IgG1 ([225Ac]hu11B6-IgG1) has shown promising treatment efficacy. In the present study, we investigated options to enhance and optimize [225Ac]hu11B6 treatment. First,

https://www.medicin.lu.se/evenemang/frontiers-neuroscience-seminar-modulation-microglia-activation-alzheimers-disease-future-treatment - 2026-05-20

https://www.geriatrik.lu.se/geriatrics/education - 2026-05-19

BACKGROUND: Brief admission by self-referral, a novel crisis intervention designed to reduce suicide and self-harm in adults, was adopted for adolescents in paediatric psychiatry in Malmö, Sweden, in 2018. We aimed to investigate changes in utilisation of emergency psychiatric care.METHODS: We did an observational longitudinal cohort study in The University Hospital in Malmö, Sweden, which provide

https://www.iac.lu.se/calendar/book-release-creative-data-lab - 2026-05-19

PhD research project: "Redefining Contemporary Guitar Performance Practice through Spherical Amplification via S.T.OOGE"PhD supervisor: Michael Edward EdgertonInstitution: Malmö Academy of MusicPeriod: November 2023 – October 2027The use of amplification technologies is an integral part of contemporary guitar practice, given the dynamic limitations of the classical guitar and the inherent nature o

https://www.iac.lu.se/research/doctoral-students/francesco-palmieri - 2026-05-19

https://www.arts.lu.se/calendar/book-release-creative-data-lab - 2026-05-19

For students of the law programme, the faculty offers one masters level course during the summer of 2025. Summer courses for those who want to study law onlineWe have extensive experience in organising distance learning and our courses are currently some of the most popular at the university. The courses consist of professionally recorded video lectures, exercises and tests. During the course, you

https://www.law.lu.se/study/online-summer-courses - 2026-05-19

https://www.ses.lu.se/utbildning/studieinformation/kursplaner-litteraturlistor-och-utbildningsplaner/kursplaner-litteraturlistor-kandidatprogrammet-service-management/kursplaner-litteraturlistor-service-management-9 - 2026-05-19