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Association of maternal serum concentrations of 2,2 ', 4,4 ' 5,5 '-hexachlorobiphenyl (CB-153) and 1,1-dichloro-2,2-bis (p-chlorophenyl)-ethylene (p,p '-DDE) levels with birth weight, gestational age and preterm births in Inuit and European populations

Background: Epidemiological studies on the association between maternal exposure to persistent organic pollutants (POPs) and fetal growth alteration report inconsistent findings which weights in favor of additional studies. Methods: Blood samples were collected from interviewed pregnant women in Greenland (572), Kharkiv (611) and Warsaw (258) and were analyzed for CB-153 and p,p'-DDE by gas chroma

The environment on holidays or how a recycling bin informs us on the environment

Purpose: This study explores how people account for their translation, negotiation and shaping of environmentally relevant practices as information practices in their everyday life during the holidays and asks further how these narratives can be seen as accounting for situated information practices. It focuses on how summer guests holidaying in southern Sweden talk about how they connect different

Contractile properties during development of hypertrophy of the smooth muscle in the rat portal vein

Structural and mechanical alterations during hypertrophy of the rat portal vein were investigated. Growth of the vessel was induced by a partial ligature of the vessel causing an increased transmural pressure. Vessel segments from animals kept with ligature for 1, 3, 5 and 7 days, were compared with vessels from sham-operated animals. Maximal active force and vessel cross-sectional area increased

Transforming growth factor-beta down-regulates apolipoprotein M in HepG2 cells.

Apolipoprotein M (apoM) is a novel apolipoprotein presented mostly in high-density lipoprotein (HDL) in human plasma, and is exclusively expressed in liver and in kidney. The pathophysiological function of apoM has not yet been elucidated. Apolipoprotein B (apoB), the characteristic apolipoprotein of low-density lipoprotein (LDL), is like apoM, a very hydrophobic protein, and thereafter they both

Incidence of asthma in female Swedish hairdressers.

OBJECTIVE: To investigate the risk of asthma in hairdressers. METHODS: The incidence of asthma was retrospectively estimated in a Swedish nationwide study including all female hairdressers certified from vocational schools from 1970 to 1995, and a stratified sample of women from the general population were referents. A postal questionnaire included questions on respiratory tract symptoms, atopy, s

Conceptual Runoff Models for Material Transport Estimations

Catchment-scale material transport models are today important tools for water and environmental management. However, modelling of material transport is extremely complex due to the physical, chemical and biological processes involved. The complexity calls for spatial distribution and thereby a need for large amounts of input data that generally are not available. Lumped models based on conceptual

Anthropometry in 5-to 9-Year-Old Greenlandic and Ukrainian Children in Relation to Prenatal Exposure to Perfluorinated Alkyl Substances

BACKGROUND: In some animal studies, perfluorinated alkyl substances are suggested to induce weight gain. Human epidemiological studies investigating these associations are sparse. OBJECTIVE: We examined pregnancy serum concentrations of perfluorooctanoate (PFOA) and perfluoro-octane sulfonate (PFOS) and the prevalence of offspring overweight (> 1 SD) and waist-to-height ratio (WHtR) > 0.5 at 5-9 y

Polymorphisms in Iron Homeostasis Genes and Urinary Cadmium Concentrations among Nonsmoking Women in Argentina and Bangladesh.

BACKGROUND: Cadmium (Cd) is a human toxicant and carcinogen. Genetic variation might affect long-term accumulation. Cadmium is absorbed by iron transporters. OBJECTIVES: To evaluate the impact of iron homeostasis genes (divalent metal transporter 1 SLC11A2; transferrin TF; transferrin receptors TFR2 and TFRC; ferroportin SLC40A1) on Cd accumulation. METHODS: Subjects were non-smoking women living

Islet constitutive nitric oxide synthase and glucose regulation of insulin release in mice

We have studied, by a combined in vitro and in vivo approach, the relation between the inhibitory action of N(G)-nitro-l-arginine methyl ester (L-NAME), a selective inhibitor of nitric oxide synthase (NOS), on the activity of islet constitutive NOS (cNOS) and glucose regulation of islet hormone release in mice. The cNOS activity in islets incubated in vitro at 20 mM glucose was not appreciably aff

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At the turn of the Century the man/woman-relationship was debated in media, public leisure life and in the genre of self help literature. The “Heterosexual Couple” was – and is - portrayed in a number of culturally fixed and thematic ways, often conceptualized via the dichotomies of Male and Female, harmony and conflict, the traditional and the modern, ideal and reality. In this thesis different

Mexican Mural Movement. Myths and Mythmakers

The aim of this study of the Mexican Mural Movement is to analyze the myths it expressed and the myths it produced. The two main characters of my study are the minister José Vasconcelos and the painter Diego Rivera, because I believe these two personalities are indispensable for an understanding of the myths surrounding the Mexican Mural Movement. While the painter is well known, the personality a

Escherichia coli Fimbriae, Bacterial Persistence and Host Response Induction in the Human Urinary Tract

Popular Abstract in Swedish Urinvägsinfektioner (UVI) är en av våra vanligaste infektionssjukdomar och orsakas oftast av bakterien Escherichia coli (E. coli). Infektionernas svårighetsgrad varierar, beroende på samspelet mellan bakterie och värd. Njurbäckeninflammation kan orsaka allvarliga störningar av njurfunktionen och kan till och med vara livshotande. Blåskatarr är en mindre allvarlig sjukdoUrinary tract infections (UTI) are among the most common bacterial infections in humans. Symptomatic UTIs may be acute, recurrent or chronic but the most frequent form of UTI is asymptomatic bacteruria (ABU). In ABU, the mucosa remains inert, despite the presence of large bacterial numbers in urine. The difference in disease severity reflects the virulence of the infecting strain and the propensit

Lymphocyte and monocyte flow cytometry immunophenotyping as a diagnostic tool in uncharacteristic inflammatory disorders.

ABSTRACT: BACKGROUND: Patients with uncharacteristic inflammatory symptoms such as long-standing fatigue or pain, or a prolonged fever, constitute a diagnostic and therapeutic challenge. The aim of the present study was to determine if an extended immunophenotyping of lymphocytes and monocytes including activation markers can define disease-specific patterns, and thus provide valuable diagnostic i

Incidence of malignancy in patients treated for antineutrophil cytoplasm antibody-associated vasculitis: follow-up data from European Vasculitis Study Group clinical trials.

OBJECTIVES: /st> Because standard immunosuppressive treatment for antineutrophil cytoplasm antibody-associated vasculitis (AAV) (granulomatosis with polyangiitis (Wegener's) (GPA) and microscopic polyangiitis (MPA)) has been associated with a significant risk of developing cancer, the cancer incidence of treated AAV patients was assessed. METHODS: /st> This analysis concerned 535 patients with new

Associations between Urinary Excretion of Cadmium and Proteins in a Nonsmoking Population: Renal Toxicity or Normal Physiology?

BACKGROUND: Associations between cadmium (Cd) and kidney function have been reported even at low levels of exposure in the general population. Recently, the causality of these associations has been questioned. OBJECTIVES: We examined associations between urinary Cd (U-Cd; a biomarker of exposure) and urinary proteins that are used as biomarkers of kidney effects, based on repeated short-term sampl

Emerging Principles in Obstetric Teamwork

There is widespread consensus that teamwork constitutes one of the key requirements in today’s multidisciplinary and highly complex system of delivering care. In recent years, increasing attention has been given to questions of how to define, teach, measure, and improve teamwork in healthcare. However, one cannot help but feel a certain disconnect between this ongoing trend, with an associated bia

HPV testing, methylation and genotyping in cervical cancer screening and treatment follow-up

HPV testing has a higher sensitivity than cytology for identification of women at risk of cancer. Primary HPV testing was introduced in the organized screening program in Skåne, Sweden in 2017 for women 30 years and older. High-risk HPV E6/E7 mRNA was detected in 7.0% of these women. Primary HPV-screening identified a similar proportion of abnormal cytology (ASCUS+) as cytology-based screening (3.

Catalytic conversion of CO2 and lignin into valuable chemicals

Increasing concern regarding climate change and environmental sustainability have driven research regarding the development of innovative solutions for CO₂ mitigation and biomass utilization. This thesis explores the catalytic conversion of CO₂ and lignin into valuable chemicals, as a promising approach to achieving carbon neutrality and enhancing the circular economy. The study focused on two key

Prenatal exposure to a mixture of per- and polyfluoroalkyl substances (PFAS) and lung function and immune-related outcomes among males in childhood and young adulthood

Background: Prenatal exposure to per- and polyfluoroalkyl substances (PFAS) may influence lung and immune system development, but previous epidemiological studies are inconclusive and have not extended into young adulthood. Objective: To examine associations between prenatal exposure to a mixture of PFAS and respiratory and immune-related outcomes in a cohort of males. Methods: We studied 866 male

Phase dependent luminescence properties of Pr3+ doped BaLu2F8–BaLuF5 materials

This work presents a comparative luminescence study of Pr3+ doped phase-pure BaLuF5 and mixed-phase BaLu2F8 – BaLuF5 materials synthesized via a hydrothermal route. The spectroscopic studies were mainly performed for phase-pure BaLuF5 and two mixed-phase materials, which, according to structural and phase compositional analysis, contained 90 or 70 wt% of orthorhombic BaLu2F8 and 10 or 30 wt% of cu