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Regular prophylactic treatment with factor VIII (FVIII) and factor IX (FIX) concentrates in hemophilia A and B, respectively, is introduced in early infancy and has resulted in dramatic improvement of the conditions. Recombinant FVIII and FIX concentrates have been available for > 25 years and have been modified and refined through the years; however, unfortunately frequent intravenous administrat

EndoS from Streptococcus pyogenes efficiently hydrolyzes the functionally important and conserved N-linked glycan of IgG in human blood. Repeated i.v. administration of EndoS in rabbits completely hydrolyzes the glycans of the whole IgG pool, despite the generation of anti-EndoS antibodies. EndoS administration had no apparent effects on the health of the animals. EndoS hydrolysis of the IgG glyca

We have characterized 2 distinct mechanisms through which infectious agents may promote platelet adhesion and thrombus formation in flowing blood, thus contributing to the progression of disease. In one case, the process initiates when the integrin alpha(IIb)beta(3) mediates platelet arrest onto immobilized bacterial constituents that have bound plasma fibrinogen. If blood contains antibodies agai

https://www.geriatrik.lu.se/geriatrics/education - 2026-05-07

The royal Danish-Norwegian flagship Gribshunden, launched in 1485, was amongthe earliest northern European warships purpose-built to carry artillery. However, King Hans employed his vessel as far more than a weapons platform. The ship was his ‘floating castle’, fulfilling all the various purposes of a land redoubt. At its loss in 1495 enroute to a political summit in Kalmar, where Hans expected to

Tim Ingold’s critique of mainstream modern experiences of human–environmental relations is highly persuasive but almost completely disconnected from considerations of social relations of power and inequality. His emphasis on the phenomenology of local relations seems inevitably detached from the logic of abstract economic and political systems. This article proposes that the distortions of experie

Studiens syfte var att undersöka hbtq+-personers upplevelser och hantering av minoritetsstress i nära relationer samt upplevda konsekvenser på hälsan och de nära relationerna. Detta gjordes genom semistrukturerade intervjuer med tio personer, som bröt mot cis- och/eller heteronormen. En tematisk analys av berättelserna utmynnade i tre huvudteman: Omvänd skuld- och ansvarsfördelning, Två sidor av mThe aim of this study was to explore how LGBTQ+ people experience and cope with minority stress in their close relationships, how minority stress affects the relationships and what health implications might come from it. Ten semi-structured interviews were conducted with LGBTQ+ individuals. A thematic analysis of the stories resulted in three main themes: Reverse guilt and liability, Two sides of

Modulenthus is a company in the wood house industry that builds houses in volumes. Volume building means that Modulenthus builds predecorated house volumes in a factory and transports these to the building sites where they are being put together to complete detached houses. The purpose of these Master Thesis is that, on the basis of Modulenthus conditions and wishes, evaluate a possible using of a

Recent studies have highlighted how building resilience to ‘shrinking’ episodes, as opposed to increasing growth rates, appears to be the missing piece of the puzzle when it comes to between-country income convergence. All economies seem to be able to grow, but few countries have been able to drastically improve their shrinking patterns, which has underpinned the divergence often argued in literat

The royal Danish-Norwegian flagship Gribshunden, launched in 1485, was amongthe earliest northern European warships purpose-built to carry artillery. However, King Hans employed his vessel as far more than a weapons platform. The ship was his ‘floating castle’, fulfilling all the various purposes of a land redoubt. At its loss in 1495 enroute to a political summit in Kalmar, where Hans expected to

Background: A significant proportion of patients with asthma have persistent symptoms despite treatment with inhaled glucocorticosteroids. Objective: We hypothesized that in these patients, the alveolar parenchyma is subjected to mast cell-associated alterations. Methods: Bronchial and transbronchial biopsies from healthy controls (n = 8), patients with allergic rhinitis (n = 8), and patients with

Thanks to the Internet, User-generated translated (UGT) material has spread at an impressive rate. Not much research exists on the subject as of the writing of this thesis, since it is a relatively new field within Translation Studies. It is an interesting topic worth exploring nonetheless. This phenomenon began in the 1980s, where these fan-translations had to be done by manually changing the vid

As a major buyer of steel, the construction sector is uniquely positioned to advance the decarbonization of global steel through increasing the demand for green steel. To unlock this potential, deepened international collaborations on green public procurement, climate policies, and trade are needed.