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Master’s Dissertation Structural Mechanics JIMMY PERSSON Report TV SM -5181 JIM M Y PERSSO N N U M ER IC A L A N A LY SIS O F C O M PR ESSIO N PER PEN D IC U LA R TO TH E G R A IN IN G LU LA M B EA M S W ITH A N D W ITH O U T R EIN FO R C EM EN T NUMERICAL ANALYSIS OF COMPRESSION PERPENDICULAR TO THE GRAIN IN GLULAM BEAMS WITH AND WITHOUT REINFORCEMENT Detta är en tom sida! Copyright © 2011 by Str

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Efficacy of rfixfc versus rix-fp for the treatment of patients with hemophilia b : Matching-adjusted indirect comparison of b-long and prolong-9fp trials

Purpose: In patients with hemophilia B, treatment with extended half-life (EHL) recombi-nant factor IX allows for longer dosing intervals while providing equal or superior bleeding protection compared with standard half-life products. This enables flexible, individualized treatment schedules, which reduce the burden of prophylaxis and improve patient outcomes. This analysis compared the efficacy o

Adsorption, desorption, and redox reactions at iron oxide nanoparticle surfaces

Soils play a critical role in the carbon (C) cycle by regulating the atmospheric carbon dioxide (CO2) levels, and correspondingly the Earth’s climate. However, there are still countless questions of how biological and geochemical soil processes affect the C cycle. To be able to predict future implications on the Earth’s climate, we need to understand these processes. Globally, soils store more C tIron oxide nanoparticles are involved in several important biogeochemical processes. The interfaces between aqueous solutions and iron oxide nanoparticle surfaces are found everywhere in nature, and the chemical and microbial processes occurring at these complex interfaces control e.g. nutrient and contaminant availability and transport. Recently, it has been shown that certain ectomycorrhizal (EC

Demonstration of antibody‐associated cellular cytotoxicity in patients with acute myelogenous leukemia before and after chemotherapy

This study demonstrates that a cytotoxic serum reactivity not requiring the presence of complement appears in the sera of patients with acute myelogenous leukemia. The reaction is detected upon short‐term incubation of sera in vitro with autochthonous mononuclear white blood cells from peripheral venous blood of patients at the acute stage of the disease. This reactivity was demonstrated in 18/18

The engineered CD80 variant fusion therapeutic davoceticept combines checkpoint antagonism with conditional CD28 costimulation for anti-tumor immunity

Despite the recent clinical success of T cell checkpoint inhibition targeting the CTLA-4 and PD-1 pathways, many patients either fail to achieve objective responses or they develop resistance to therapy. In some cases, poor responses to checkpoint blockade have been linked to suboptimal CD28 costimulation and the inability to generate and maintain a productive adaptive anti-tumor immune response.

Host-pathogen interactions in Streptococcus pyogenes infections, with special reference to puerperal fever and a comment on vaccine development.

Streptococcus pyogenes (group A streptococcus) causes a variety of diseases, including acute pharyngitis, impetigo, rheumatic fever and the streptococcal toxic shock syndrome. Moreover, S. pyogenes was responsible for the classical example of a nosocomial infection, the epidemics of puerperal fever (childbed fever) that caused the death of numerous women in earlier centuries. The most extensively

Rod-Shaped Monocytes Patrol the Brain Vasculature and Give Rise to Perivascular Macrophages under the Influence of Proinflammatory Cytokines and Angiopoietin-2

The nervous system is constantly infiltrated by blood-derived sentinels known as perivascular macrophages. Their immediate precursors have not yet been identified in situ and the mechanism that governs their recruitment is mostly unknown. Here, we provide evidence that CD68 (+)GR(-) monocytes can give rise to perivascular macrophages in mice suffering from endotoxemia. After adhesion to the endoth

Severe streptococcal infection is associated with M protein-induced platelet activation and thrombus formation.

Disturbed haemostasis is a central finding in severe Streptococcus pyogenes infection. In particular, microthrombi are found both at the local site of infection and at distant sites. Platelets are responsible for maintaining vascular function and haemostasis. We report here that M1 protein of S. pyogenes triggers immune-mediated platelet activation and thrombus formation. M1 protein is released fr

Dry release of suspended nanostructures

A dry release method for fabrication of suspended nanostructures is presented. The technique has been combined with an anti-stiction treatment for fabrication of nanocantilever based nanoelectromechanical systems (NEMS). The process combines a dry release method, using a supporting layer of photoresist which is removed using oxygen ashing in a reactive ion etcher (RIE), with CHF3 plasma induced de

Review of exergy and energy analysis of fuel cells

Recently, to reach zero emission levels, some new energy systems based on fuel cells have been developed. This paper presents a review of investigations of these systems by thermodynamics performance, mainly, energy and exergy analysis. With energy analysis, the performance of an energy conversion system cannot be effectively and accurately evaluated. But exergy analysis complements and reinforces

Receptor for IgA in group A streptococci : cloning of the gene and characterization of the protein expressed in Escherichia coli

The gene for an IgA-binding protein from a group A streptococcal strain was cloned and expressed in Escherichia coli. The IgA-binding protein, called protein Arp, was purified on IgA-Sepharose, allowing complete purification in a single step. Analysis of protein Arp by Western immunoblotting demonstrated a major IgA-binding band, with an apparent molecular weight of 42 kD. The purified protein was

Determinants of Corruption - a Study of Zambian Ministries

Corruption is indisputably an immense obstacle for many developing countries in their endeavor to prosper economically. Zambia, a peaceful, politically stable democracy is still facing many of the problems connected with corruption. Corruption has so far mostly been measured on a state-level, but in our thesis we narrow the field of investigation down to the ministry-level. We use questionnaires t

Clinical studies of extended-half-life recombinant FVIII products for prophylaxis in adults and children : A critical review from the physician's perspective

This review compares the methodology of published clinical studies investigating the extended-half-life (EHL) factor VIII (FVIII) products, rFVIIIFc (efmoroctocog alfa, Elocta®/Eloctate®), BAY 94-9027 (damoctocog alfa pegol, Jivi®), BAX 855 (rurioctocog alfa pegol, Adynovate®) and N8-GP (turoctocog alfa pegol, Esperoct®) including the phase 2/3 studies, A-LONG (NCT01181128), PROTECT VIII (NCT01580

Interim Report on Gribshunden (1495) Excavations: 2019–2021

We present an interim archaeological report on the ship- wreck of the Danish-Norwegian flagship Gribshunden. Built in 1485, extensively employed by King Hans as his floating castle, and ultimately lost in June 1495 en route to Kalmar, the ship carried people and material selected to further the political goal of re-unifying the Nordic region. Three field campaigns led by Lund University and Blekin

Lakatos's challenge? : Auxiliary hypotheses and non-monotonous inference

Gerhard Schurz [2001, Journal for General Philosophy of Science, 32, 65-107] has proposed to reconstruct auxiliary hypothesis addition, e.g., postulation of Neptune to immunize Newtonian mechanics, with concepts from non-monotonous inference to avoid the retention of false predictions that are among the consequence-set of the deductive model. However, the non-monotonous reconstruction retains the