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Assessment of drift in the Immunotechnology cell line MUTZ-3

Analys av immunteknologis MUTZ-3 visar tecken på genetisk drift Allergi är en vanligt förekommande sjukdom som drabbar en stor del av befolkningen. Sjukdomen kan ta många olika former och vanliga typer är matallergi, luftvägsallergi och kontaktallergi. Kontaktallergi uppstår när en person kommer i upprepad kontakt med kemikalier som kan aktivera immunförvaret. Immunförsvarets är ett komplext nätveThe continued increased exposure to chemicals and the increasing prevalence of allergic contact dermatitis makes it important to develop accurate testing methods and strategies to assess chemical sensitizers. The Genomic Allergen Rapid Detection (GARD) assay is an in vitro test method that uses the transcriptional response of a myeloid cell line, MUTZ-3, after exposure to test substances to assess

Safety and Security in Sudan: Humanitarian Aid Workers’ Risk Perception

Protection of humanitarian aid workers (HAWs) is a challenging task. There are various reports on the topic where much research seems to focus on traditional physical attacks and intentional violence against HAWs (security) rather than the accidental event risks (safety) or discussing it separately. These risks are usually defined by the organization’s security risk management holding the power in

Onlinedejting - ”det är liksom inte svart och vitt” : En enkätstudie om olika generationers attityder till onlinedejting i Sverige

In less than two decades, online dating services have gone from being seen as a marginal and stigmatised practice, to being a regular activity in people's social and romantic lives. This thesis intends to examine Swedish attitudes towards the digital phenomena of online dating and online dating services. The study was conducted through a quantitative method in the form of an online survey, wit

Hit, men inte längre! – En granskning av målsägandens begränsade rätt till målsägandebiträde i hovrättsprocessen ur ett brottsofferperspektiv

Lagen (1988:609) om målsägandebiträde, vilken medger en rätt till biträde för brottsoffer som utsatts för särskilt allvarlig brottslighet, har varit en central lagstiftning för att stärka brottsoffrets intressen i rättsprocessen. Till följd av en lagreform som genomfördes år 2018 har dock rätten begränsats i högre rätt. Detta har i sin tur mötts av omfattande kritik med hänsyn till brottsoffrens iThe Act (1988:609) on Counsel for Injured Parties, which grants the right to counsel for victims of particularly serious crimes, has been a significant piece of legislation for strengthening the interests and rights of crime victims within the legal process. However, a legal reform enacted in 2018 has limited this right in higher courts. This has been met with extensive criticism concerning the in

Burning Questions: Community Engagement and Wildfire Management in a Changing Climate. A case study of Kamloops, British Columbia, Canada

As Climate Change increases the frequency and severity of wildfires in British Columbia, communities at the Wildland Urban Interface face escalating risks. This thesis explores the challenges and opportunities of community engagement in wildfire management in the city of Kamloops, one of the most fire-prone urban areas in British Columbia. Employing a single-case study design, the research is base

Inkomstfördelningens roll för den ekonomiska tillväxten

This essay investigates the impact of income inequality on economic growth in developed countries. The link is primarily investigated through the possible influence of income inequality on the four growth channels savings, human capital, population growth and labor force productivity. A theoretical model, based on an extended version of the Romer model, is presented, where a higher degree of incom

A General Purpose Near Data Processing Architecture Optimized for Data-intensive Applications

In recent years, as Internet of Things (IoT) and machine learning technologies have advanced, there has been increasing interest in the study of energy-efficient and flexible architectures for embedded systems. To bridge the performance gap between microprocessors and memory systems, Near-Data Processing (NDP) was introduced. Although some works have implemented NDP, few of them utilize the microp

Nitrification performance in a novel biofilm process based on external biofilm growth : Effects of carrier surface area and substrate limitations

En ökande användning av ammonium genom samhälls- och industriell utveckling hotar utvatten runt om i världen. För att skydda det akvatiska ekosystemet och dricksvattenresurserna kan ammonium avlägsnas med biologisk behandling vid avloppsreningsverk. Utvecklingen av avloppsreningsverk under det senaste århundradet syftar till att implementera lösningar som är kostnads- och energieffektiva, har en lAn increasing usage of ammonium through societal and industrial development is threatening the water bodies around the world. To protect the aquatic ecosystem and drinking water resources, ammonium can be removed with biological treatment at wastewater treatment plants (WWTP). The development of WWTPs in the last century is aiming to implement solutions, which are cost and energy efficient, have a

The European Union and the Fight Against Corruption: A Pre- and Post-Accession Study

This thesis investigates whether corruption levels in European Union (EU) member states have changed following their accession, with a particular focus on countries joining after the establishment of the Copenhagen Criteria in 1993. Employing a mixed-methods approach, the study first conducts a quantitative analysis of corruption trends on a year-by-year basis across all post-1993 accession countr

Lokala litterära nätverk. Kartläggning och jämförelse av nätverk mellan litterära aktörer i Unescos litteraturstäder

This master’s thesis maps and compares local literary networks within UNESCO’s Cities of Literature, with the aim of understanding how such networks are structured, what their functions are and how they are controlled and developed. Drawing on concepts from social network analysis and Bourdieu’s theories of social fields, capital and habitus, the study combines quantitative and qualitative methods

Sleepy Network Devices: Implementation and Energy Modeling of Low-Power Proxying Solutions

As the industrial, commercial, and domestic prevalence of Internet of Things networks grows, so does the search for viable solutions to decrease their energy consumption. One common solution is using a low-power proxy that can control the power state of the devices within the network. To evaluate such solutions, either implementations can be made and measured for energy consumption, or energy mode

Microclimatic Refugia and Pollinator Resilience: The Role of Fine-Scale Climatic Variation in Semi-Natural Grasslands

Små klimatfickor – stor betydelse Bin, fjärilar och blomflugor är inte bara vackra att titta på – de gör också ett av naturens viktigaste jobb. Genom att flytta pollen mellan blommor ser de till att många växter kan föröka sig. Det gäller både vilda arter och en stor del av de grödor som vi människor äter. Utan dessa pollinatörer skulle vår biologiska mångfald minska kraftigt, och även vår livsmePollinators are essential for biodiversity and ecosystem services but face growing threats from climate change. Microclimates may buffer these impacts by providing localized climatic refugia. I assessed community-level and body size-dependent responses of bees, butterflies, and hoverflies to microclimatic temperature, humidity, wind, and structural shelter in semi-natural grasslands in southern Sw

Metabolic engineering of yeast for improved whole-cell biocatalytic amine production

Saccharomyces cerevisiae has emerged as a versatile platform for whole-cell biocatalysis, owing to its intrinsic regeneration of cofactors and amenability to genetic engineering. However, efficient reductive amination of aromatic carbonyls remains challenging due to competing redox pathways and product inhibition by pyruvate. Building on the redox-rewired TMB4133 strain (∆gpd1,2) that accumulates

‘Ghost’ fossils of early coccolithophores point to a Triassic diversification of marine calcifying organisms

Over geologic time, biocalcification – the process by which marine organisms make calcium carbonate (CaCO3) – has reshaped climates, ocean life, and seawater chemistry. In particular, the evolution of coccolithophores, the largest group of nannoplankton and today’s most productive calcifiers, transformed ocean environments and the carbon cycle. Their origins, however, remain enigmatic. This is par

Home-based Hybrid Assistive Limb Lumbar Type Telerehabilitation in Spinocerebellar Ataxias : A Nonrandomized Open-label Trial

A hybrid assistive limb (HAL) can improve the motor performance of patients with various neurodegenerative diseases, but the efficacy of home-based rehabilitation using HAL for spinocerebellar ataxias (SCA) has yet to be elucidated. To evaluate the efficacy and safety of home-based telerehabilitation with lumbar type HAL in patients with SCA. In this non-randomized open-label single center trial,

Longitudinal decline in upper-limb range of motion in adults with cerebral palsy

To analyse longitudinal changes in passive range of motion (ROM) in the upper limb in adults with cerebral palsy (CP). Method: Passive ROM for shoulder abduction and flexion, supination, and elbow and wrist extension was analysed in a longitudinal cohort of adults aged 16 to 76 years from the Swedish CP registry. Individual ROM trajectories and mean ROM curves were calculated using the Manual Abil

Gamma decay of high spin states in Mg25 above 6.1 MeV

New high spin states in Mg25 (up to 13.3 MeV in excitation) have been located using the N12,p)25Mg reaction at a laboratory beam energy of 23.5 MeV. Gamma decay from 28 neutron unbound levels has been observed (24 of which are reported here for the first time) up to 7 MeV above the neutron drip line. Tentative identification of the yrast line up to (17/2+ has been made, along with an extension of