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Developing AIDS, A study of AIDS in the context of other social problems in New Crossroad, Cape Town

Development is often looked upon in economical terms and often research tries to investigate how one country can produce or sell more in order to increase its GDP. This thesis does not exclude these considerations but focuses on health as an important aspect of development. I investigate why South Africans (SA) would place their lives at risk with full knowledge of AIDS by not using freely availab

Evaluation of the Elekta Synergy concept for patient positioning in image guided radiotherapy

Introduction: The Elekta Synergy machine for external beam radiation therapy is equipped with an x-ray tube for on-line kV imaging and correction of the patient setup. The system can provide both 2D and 3D data for image guided radiotherapy (IGRT). Different aspects of the imaging system (called XVI) has been evaluated, such as image quality, flex of the gantry rotation, accuracy for patient setup

Molds and mycotoxins in indoor environments - a survey in water-damaged buildings.

Mycotoxins are toxic, secondary metabolites frequently produced by molds in water-damaged indoor environments. We studied the prevalence of selected, potent mycotoxins and levels of fungal biomass in samples collected from water-damaged indoor environments in Sweden during a 1-year period. One hundred samples of building materials, 18 samples of settled dust, and 37 samples of cultured dust were a

Facing Mortality: A Meta-Analysis and Systematic Review of Psychedelic Experiences and Death Anxiety

This meta-analysis and systematic review examined the effects of psychedelic substances on death anxiety, specifically evaluating whether psychedelic experiences are associated with statistically significant reductions in death anxiety. Studies were eligible if they quantitatively assessed death anxiety or death acceptance using validated measures, or qualitatively explored attitudes toward death

Sleepy Network Devices: Implementation and Energy Modeling of Low-Power Proxying Solutions

As the industrial, commercial, and domestic prevalence of Internet of Things networks grows, so does the search for viable solutions to decrease their energy consumption. One common solution is using a low-power proxy that can control the power state of the devices within the network. To evaluate such solutions, either implementations can be made and measured for energy consumption, or energy mode

Microclimatic Refugia and Pollinator Resilience: The Role of Fine-Scale Climatic Variation in Semi-Natural Grasslands

Små klimatfickor – stor betydelse Bin, fjärilar och blomflugor är inte bara vackra att titta på – de gör också ett av naturens viktigaste jobb. Genom att flytta pollen mellan blommor ser de till att många växter kan föröka sig. Det gäller både vilda arter och en stor del av de grödor som vi människor äter. Utan dessa pollinatörer skulle vår biologiska mångfald minska kraftigt, och även vår livsmePollinators are essential for biodiversity and ecosystem services but face growing threats from climate change. Microclimates may buffer these impacts by providing localized climatic refugia. I assessed community-level and body size-dependent responses of bees, butterflies, and hoverflies to microclimatic temperature, humidity, wind, and structural shelter in semi-natural grasslands in southern Sw

Metabolic engineering of yeast for improved whole-cell biocatalytic amine production

Saccharomyces cerevisiae has emerged as a versatile platform for whole-cell biocatalysis, owing to its intrinsic regeneration of cofactors and amenability to genetic engineering. However, efficient reductive amination of aromatic carbonyls remains challenging due to competing redox pathways and product inhibition by pyruvate. Building on the redox-rewired TMB4133 strain (∆gpd1,2) that accumulates

Development of an evidence-based website on preconception health

Introduction: Many women and men lack knowledge about fertility, including timing of the fertile window, age-related decline, and lifestyle factors that may impair fertility. The Internet has become an important source of information, but evidence-based information on fertility and reproduction in Swedish on the Internet is limited. The present study aimed to develop and evaluate an evidence-based

Sanding a slippery genre : Making sense of the kappa in STEM

In this roundtable, we will discuss the role of the kappa, the framing text in a compilation thesis, in STEM doctoral education. Based on two runs of the new courseFraming your research – thesis frames and knowledge contribution for doctoral students at LTH and a focus group discussion with experienced examination committee members and supervisors, we argue that the kappa is an emergent genrestill

‘Ghost’ fossils of early coccolithophores point to a Triassic diversification of marine calcifying organisms

Over geologic time, biocalcification – the process by which marine organisms make calcium carbonate (CaCO3) – has reshaped climates, ocean life, and seawater chemistry. In particular, the evolution of coccolithophores, the largest group of nannoplankton and today’s most productive calcifiers, transformed ocean environments and the carbon cycle. Their origins, however, remain enigmatic. This is par

Home-based Hybrid Assistive Limb Lumbar Type Telerehabilitation in Spinocerebellar Ataxias : A Nonrandomized Open-label Trial

A hybrid assistive limb (HAL) can improve the motor performance of patients with various neurodegenerative diseases, but the efficacy of home-based rehabilitation using HAL for spinocerebellar ataxias (SCA) has yet to be elucidated. To evaluate the efficacy and safety of home-based telerehabilitation with lumbar type HAL in patients with SCA. In this non-randomized open-label single center trial,

Longitudinal decline in upper-limb range of motion in adults with cerebral palsy

To analyse longitudinal changes in passive range of motion (ROM) in the upper limb in adults with cerebral palsy (CP). Method: Passive ROM for shoulder abduction and flexion, supination, and elbow and wrist extension was analysed in a longitudinal cohort of adults aged 16 to 76 years from the Swedish CP registry. Individual ROM trajectories and mean ROM curves were calculated using the Manual Abil

Gamma decay of high spin states in Mg25 above 6.1 MeV

New high spin states in Mg25 (up to 13.3 MeV in excitation) have been located using the N12,p)25Mg reaction at a laboratory beam energy of 23.5 MeV. Gamma decay from 28 neutron unbound levels has been observed (24 of which are reported here for the first time) up to 7 MeV above the neutron drip line. Tentative identification of the yrast line up to (17/2+ has been made, along with an extension of

Associations between the thermal spring timing variability and atmospheric teleconnection patterns over the past six decades in Finland

The timing of the spring season in the boreal region is shifting under global warming, with profound impacts on ecosystems and hydrological processes. However, the mechanisms driving this transition and its considerable interannual variability are not well described, especially regarding the influence of large-scale atmospheric teleconnection patterns. This study examines the temporal variability

Consent and Coercion : Forced Marriages in Supplications to the Apostolic Penitentiary, 1484-1492

In the late Middle Ages, hundreds of Christians from all over Europe sent supplications to the Papal Curia to be freed from promises made under duress. This article analyses the supplications about forced marriages that were submitted to the Apostolic Penitentiary during the pontificate of Pope Innocent VIII (1484–92). The study is based on mainly unedited source material that has not been investi

Computational Evidence for a Water-Assisted Proton-Transfer Mechanism in Uronate Isomerase from Bacillus Halodurans (Bh0493)

Uronate isomerase (EC 5.3.1.12; URI) catalyzes uronate sugar interconversion, a key step in bacterial metabolism, yet its reaction mechanism remains poorly understood. This study delineates the detailed mechanism for the isomerization of d-glucuronate to d-fructuronate catalyzed by a Zn2+-dependent URI enzyme (from Bacillus halodurans). Using quantum mechanical (QM) cluster calculations, three mec

Patient perceptions about obesity management in the context of concomitant care for other chronic diseases

Background: Approximately 15% of Canadian adults live with two or more chronic diseases, many of which are obesity related. The degree to which Canadian obesity treatment guidelines are integrated into chronic disease management is unknown. Methods: We conducted a 12-min online survey among a non-probability sample of 2506 adult Canadians who met at least one of the following criteria: 1) BMI ≥30