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AimsWe aimed to investigate the association between the exercise systolic blood pressure (SBP) response and future hypertension (HTN) in normotensive individuals referred for cycle ergometry, with special regard to reference exercise SBP values and exercise capacity.Methods and resultsIn this longitudinal cohort study, data from 14 428 exercise tests were cross-linked with Swedish national registr

Background: Swedish healthcare is in a period of transition with an expanding private sector. This study compares quality of outcome after groin hernia repair performed in a public or private healthcare setting. Methods: A cohort study based on data from the Swedish National Hernia Register combined with Patient-Reported Outcome Measures (PROMs) 1 year after groin hernia repair. Between September

Flowing water impacts bridges over rivers primarily in two ways: (1) hydrodynamic forces that directly impact the structure and (2) scouring at piers and abutments, including contraction scour. The design prin-ciples for bridges in Sweden, including both impacting forces and local scour, are relatively simplistic. The purpose of this paper is to examine the impact of extreme river flows on bridges

Feathers comprise a series of evolutionary innovations but also harbour colour, a key biological trait known to co-vary with life history or complex traits. Those relationships are particularly true in melanin-based pigmentation species due to known pleiotropic effects of the melanocortin pathway – originating from melanin-associated phenotypes. Here, we explore the molecular basis of melanin colo

Deaths of despair (DoD), encompassing suicide, drug overdose, and alcohol-related mortality, are often linked to social and psychological distress. This study examined the long-term risk of DoD among individuals previously hospitalized for suicide attempts, with a focus on substance use problems and psychiatric disorders as potential risk factors. A prospective cohort of 1044 individuals admitted

Purpose of review Breathlessness is a common, distressing and limiting symptom in people with advanced disease, but is challenging to assess as the symptom intensity depends on the level of exertion (symptom stimulus) during the assessment. This review outlines how to use recently developed normative reference equations to evaluate breathlessness responses, accounting for level of exertion, for va

The study has shown that BIM is used extensively throughout the entire construction process, with clear benefits and optimizations. The broad usage of BIM shows that all areas have streamlined and become less costly. BIM is well established in the construction process with an exception for the facility management phase. The benefits in the facility management area are well studied but not introduc

Title: System Dynamics Perspective on the Business Model for Sustainability: A Multiple Case Study in the Architecture Industry Purpose: The primary purpose of the study is to explain how the system dynamics between the Value Configuration, Partner Network, and Capabilities work in a Business Model for Sustainability of small and large architecture firms. Methodology: We followed an abductive, q

Den 1 juli 2018 trädde den nya förvaltningslagen (2017:900) i kraft. I lagen ges enskilda, genom införandet av en dröjsmålstalan, för första gången i svensk förvaltningsrätt en generell rätt att föra talan mot förvaltningsmyndigheters passivitet. Om unionsrätten inte anger annat kommer den nya dröjsmålstalan, enligt principen om medlemsstaternas processuella autonomi, att tillämpas även vid förvalOn the first of July 2018, the new Swedish Administrative Procedure Act came into force. The Act introduces a new remedy against the inaction of administrative authorities (an action for failure to act, in Swedish “dröjsmålstalan”). Through the introduction of the new remedy, individuals are given a general right to appeal against the administrative authorities' inaction for the first time in

The enunciation of the principle of equality and non-discrimination is of fundamental source in international human rights laws and EU-law and has a prominent place in the Icelandic constitution. The principles of equality and non-discrimination are based on various legal concepts that have evolved mainly in international and regional human rights or equality jurisprudence. International legal pro

”Vårt samhälle blir alltmer sårbart” är säkert en formulering du känner igen. Faktum är att vårt samhälle är fullt av risker, stora som små, och för att minska dessa gör varje kommun en risk- och sårbarhetsanalys. Analysen ska bland annat hjälpa politiker att ta beslut om åtgärder som kan minska samhällets risker och i denna artikel ställer vi oss frågan om detta faktiskt händer? Risk definieras iThis thesis examines to what extent the comprehensive municipal risk and vulnerability analysis work as a basis for decision-making concerning risk and vulnerability reducing measures in eight Swedish municipalities. An additional objective is to identify mechanisms influencing the decision-making process regarding such measures. In order to meet these objectives an interview study was conducted i

Wilms' tumor gene 1 (WT1) is a transcription factor involved in developmental processes. In adult hematopoiesis, only a small portion of early progenitor cells express WT1, whereas most leukemias show persistently high levels, suggesting an oncogenic role. We have previously characterized oncogenic BCR/ABL1 tyrosine kinase signaling pathways for increased WT1 expression. In this study, we show tha

The Siemens gas turbine SGT-800 has an annular combustor and 30 dry low emission burners. In order to further reduce the emission levels and to obtain improved understanding of the flow and associated flame dynamics, single burner rig tests have been performed. The laboratory measurements are complemented by Large Eddy Simulation (LES) to analyze the effect on the flame dynamics due to the transie

Objective. To examine the appropriateness and necessity of colonoscopy across Europe. Design. Prospective observational study. Setting. A total of 21 gastrointestinal centers from 11 countries. Participants. Consecutive patients referred for colonoscopy at each center. Intervention. Appropriateness criteria developed by the European Panel on the Appropriateness of Gastrointestinal Endoscopy, u