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Studies on late effects in patients with mantle cell lymphoma (MCL) are becoming increasingly important as survival is improving, and novel targeted drugs are being introduced. However, knowledge about late effects is limited. The aim of this population-based study was to describe the magnitude and panorama of late effects among patients treated with or without high-dose chemotherapy with autologo

OBJECTIVE: Traditionally, the diagnosis of pleural mesothelioma is based on histological material. Minimally invasive effusion cytology specimens are an alternative that, like biopsies, require ancillary analyses. Validation of immunohistochemical (IHC) analyses on cytology, including the surrogate markers for molecular alterations BAP1 and MTAP, is of interest.METHODS: IHC for eight different mar

Aim: To evaluate patients’ and family members’ perceived support from light and color before, compared with after an evidence-based design (EBD) intervention at an emergency department (ED) using a validated instrument—the Light and Color Questionnaire (LCQ). Background: EDs offer acute care day and night. Thus, a supportive physical environment where light and color is crucial for how the milieu

Context. The motion of stars has been used to reveal details of the complex history of the Milky Way, in constant interaction with its environment. Nevertheless, to reconstruct the Galactic history puzzle in its entirety, the chemo-physical characterisation of stars is essential. Previous Gaia data releases were supported by a smaller, heterogeneous, and spatially biased mixture of chemical data f

Objective: The first-line approach for childhood obesity is lifestyle intervention (LI); however, success varies. This study aimed first to identify distinct subgroups of response in children living with overweight and obesity and second to elucidate predictors for subclusters. Methods: Based on the obesity patient follow-up registry the APV (Adipositas-Patienten-Verlaufsdokumentation) initiative,

Mitochondrial metabolism is entirely dependent on the biosynthesis of the [4Fe-4S] clusters, which are part of the subunits of the respiratory chain. The mitochondrial late ISC pathway mediates the formation of these clusters from simpler [2Fe-2S] molecules and transfers them to client proteins. Here, we characterized the late ISC pathway in one of the simplest mitochondria, mitosomes, of the anae

Background: The ProtonCare Study Group (PCSG) was formed with the purpose to develop and implement a framework for evaluation of proton beam therapy (PBT) and the related care at a novel clinic (Skandionkliniken), based on patient reported data. Method: A logic model framework was used to describe the process of development and implementation of a structured plan for evaluation of PBT for all diag

The first edition of Astrid Lindgren's book Pippi Langstrumpf (GDR/1975) is our starting point for this presentation. It is also our first joint presentation of our project “Pippi beyond the border” (The Foundation for Baltic and East European Studies). The aim of the project is to examine the complex reception history of Astrid Lindgren's classic children's book Pippi Longstocking in the GDR, whi

Purpose: To demonstrate the technical feasibility and the value of ultrahigh-performance gradient in imaging the prostate in a 3T MRI system. Methods: In this local institutional review board–approved study, prostate MRI was performed on 4 healthy men. Each subject was scanned in a prototype 3T MRI system with a 42-cm inner-diameter gradient coil that achieves a maximum gradient amplitude of 200 m

Background and purpose: Stereotactic body radiotherapy (SBRT) has emerged as a promising treatment for patients with ventricular tachycardia (VT) who do not respond to standard treatments. However, the management of respiratory motion during treatment remains a challenge. This study aimed to investigate the effect of abdominal compression (AC) on respiratory induced motion in the heart. Materials

OBJECTIVE: Sex steroids exert important biological functions within the central nervous system (CNS), but the underlying mechanisms are poorly understood. The contribution of circulating sex steroids to the levels in CNS tissue and cerebrospinal fluid (CSF) has been sparsely investigated in human and with inconclusive results. This could partly be due to lack of sensitive validated assays. To addr

The dominant road traffic particle sources are wear particles from the road and tire interface, and from vehicle brake pads. The aim of this work was to investigate the effect of road and brake wear particles on pulmonary function and biomarkers in isolated perfused rat lungs. Particles were sampled from the studded tire wear of three road pavements containing different rock materials in a road si

Purpose: The use of molecular radiotherapy (MRT) has been rapidly evolving over the last years. The aim of this study was to assess the current implementation of dosimetry for MRTs in Europe. Methods: A web-based questionnaire was open for treating centres between April and June 2022, and focused on 2020–2022. Questions addressed the application of 16 different MRTs, the availability and involveme

Exposure to excessive indoor radon causes around 500 lung cancer deaths in Sweden annually. However, until 2020, indoor radon measurements were only conducted in around 16% of Swedish single-family houses and 17% of multifamily houses. It is estimated that approximately 16% of single-family houses exceed the indoor radon reference level of 200 Bq/m3, and the corresponding situation in multifamily

Background: The use of methylisothiazolinone (MI) as a preservative in cosmetic products caused an alarming increase in MI contact allergy across Europe in the 2010s. This was followed by regulations of use with a total ban on leave-on (implemented in 2017) and reduced use concentrations in rinse-off cosmetics (2018). Objective: To follow-up on the prevalence of contact allergy to MI and the relat

Aim: To explore the impact of age on the discriminative ability of the National Early Warning Score (NEWS) 2 in prediction of unanticipated Intensive Care Unit (ICU) admission, in-hospital cardiac arrest (IHCA) and mortality within 24 hours of Rapid Response Team (RRT) review. Furthermore, to investigate 30- and 90-day mortality, and the discriminative ability of NEWS 2 in prediction of long-term

BACKGROUND: Respiratory syncytial virus (RSV) and influenza cause significant health challenges, particularly for individuals with comorbid conditions and older adults. However, information on the clinical manifestations and outcomes of adults hospitalized with RSV in Europe remains limited.METHODS: This multicenter observational cohort study of adults hospitalized with RSV or influenza A or B fro

Oxygen-enriched air combustion holds promise as an effective method for harnessing blast furnace gas (BFG) in the steel industry. In this study, the laminar burning velocities of blast furnace gas were measured using the heat flux method under elevated oxygen mole fractions (0.3–1.0) and temperatures (303–353 K). Subsequently, the measured data were used to evaluate the GRI-Mech 3.0, Li, FFCM-1, a

We have investigated the possibility of using the 2.45 GHz ISM band for communication between binaural hearing aids. The preliminary investigations were done by FDTD simulations on a modified SAM phantom head, where we have included a simple model of the ear canal. Two different types of hearing aid placements have been investigated: in the outer ear and in the ear canal. Antennas which have been