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OBJECTIVES: To analyze the initial clinical and radiological findings, the surgical treatment, and the clinical outcome following surgical decompression in patients with space-occupying bilateral cerebellar infarction.MATERIALS AND METHODS: Ten patients with expansive bilateral cerebellar infarction and decreased level of consciousness were operated with suboccipital craniectomy, removal of the in
Aims/hypothesis: It has been shown that children previously enrolled in follow-up studies have better glycaemic control during the early period after diabetes diagnosis. The aim of this study was to analyse glycaemic control over a longer period, past the period of partial remission, after diagnosis in children followed before diagnosis in the Swedish Diabetes Prediction in Skåne (DiPiS) study com
BACKGROUND AND AIMS: The aims of this study were to investigate (1) if P2Y(12) polymorphisms defining the P2Y(12) H2 allele are associated with any other SNPs that may explain the previously reported association with increased ADP induced platelet activation and association with peripheral arterial disease and coronary artery disease and (2) if such variants are associated with acute myocardial in
BACKGROUND: Hormone-sensitive lipase (HSL) is a key enzyme in the mobilization of fatty acids from stored triacylglycerols. Its activity is regulated by reversible protein phosphorylation. In rat HSL Ser563, Ser659 and Ser660 have been shown to be phosphorylated by protein kinase A (PKA) in vitro as well as in vivo. METHODOLOGY/PRINCIPAL FINDINGS: In this study we employed site-directed mutagenesi
Fatty acids (FA) have crucial functions in animals, affecting e.g. inflammatory responses, thermoregulation, and cell membrane fluidity. Diet and ambient temperature affect animals’ FA composition, which, in turn, may influence these physiological processes. Great tit (Parus major) −common in both urban and rural habitats− are mainly granivorous during winter and insectivorous during summer. These
The aim of this thesis was to study maternal emotional impact on the fetus and on pregnancy outcome. The thesis comprises five papers, which emanate from a prospective study regarding life situation, the experience of pregnancy, anxiety (Spielberger State-Trait Anxiety),and life events in nulliparous women, conducted in Malmö during 1988-1989. Examinations of fetal hemo-dynamics, fetal movements,
MASTER (MAnaging Speeds of Traffic on European Roads) aims to provide recommendations for speed management strategies and policies and to elaborate guidelines for the development of innovative speed management tools. Within the framework of the project, field trials with a car equipped with a speed limiter were carried out in three “regional typical” European countries: Sweden, the Netherlands, an
In many organizations it is considered of vital importance to translate its vision and strategy into objectives, to determine the best means of achieving these and to review the results – with participation from all members, from management to shop floor. The objective of this study was to make a first test of a method that could be applied for verbalizing and communicating a common vision and ide
Background The pattern of cancer in long-term survivors from childhood cancer has not been investigated comprehensively. Methods We obtained a cohort of 47 697 children and adolescents aged 0-19 years with cancer as defined by the country-wide cancer registries of Denmark, Finland, Iceland, Norway, and Sweden during 1943-2005. Cohort members were followed through age 79 years for subsequent primar
Optimization techniques always play an important role in designing high-performance wireless systems. This presented thesis studies a selected set of optimization problems for different kinds of wireless networks, making use of mathematical programming techniques to find optimal solutions and of efficient heuristics to find near-optimal solutions. The basic contribution of the thesis consists in a
PURPOSE: To examine the incidence of and the indications for re-intervention, as well as the changes in aortic morphology, in patients with chronic type B aortic dissection who underwent endovascular intervention for false lumen aneurysms. METHODS: A retrospective analysis was conducted of 10 patients (8 men; mean age 63 years, range 45-79) who underwent stent-graft repair of aneurysmal false lume
OBJECTIVES: To characterize the clinical phenotype and to study the course of disease in patients with Alström syndrome, with an emphasis on retinal function assessed with full-field electroretinography (ERG). METHODS: Three age- and sex-matched patients with Alström syndrome were selected from our retinitis pigmentosa register for repeated ophthalmologic examinations that included tests for color
Uterine clear cell carcinoma (UCC) and uterine papillary serous carcinoma (UPSC) are rare entities that differ in clinical behavior from endometrial adenocarcinoma. Compared with endometrioid adenocarcinoma, they more often metastasize early and more commonly in the upper abdomen including the omentum. Treatment programs of UCC and UPSC at different stages vary and range from no adjuvant therapy i
A positive and innovative organizational climate is of great importance in order to manage and adapt to change. Such a climate seldom evolves in organizations closely governed by rules and regulations. Because of ongoing organizational and technical changes within the Swedish Air Navigation Services Provider, a study concerning the organizational climate for changes and innovations was conducted t
1 In the present study, the inhibitory effects of the selective beta 2-adrenoceptor agonists, salmeterol, formoterol and salbutamol, have been investigated on contractions of ferret trachea induced both by endogenous and exogenous acetylcholine. The aim of the study was to evaluate quantitative and/or qualitative differences in response which may indicate both pre-and post-junctional sites of acti
Popular Abstract in Swedish Mesenteriell ischemi (nedsatt blodcirkulation till tarm och övriga bukorgan) är vanligt förekommande vid ett flertal olika sjukdomstillstånd som t ex blödnings-, septisk och cirkulatorisk chock. Inte minst är tarmen mycket känslig för nedsättning av blodflödet. Tarmskadan, inkluderande dess barriär(skydds-)funktion sker dels under perioden med nedsatt blodförsörjning meIntestinal ischemia and reperfusion (I/R) is not infrequent in the clinical situation and the intestinal barrier plays an important role in gut barrier function, preventing not at least septic complications and potentially the development of the multiple organ dysfunction syndrome. Mechanisms of intestinal I/R induced gut epithelial and endothelial barrier dysfunction and remote organ dysfunction
Combining the strengths of an advanced mathematical model of human physiology and a thermal manikin is a new paradigm for simulating thermal behaviour of humans. However, the forerunners of such adaptive manikins showed some substantial limitations. This project aimed to determine the opportunities and constraints of the existing thermal manikins when dynamically controlled by a mathematical model
This thesis is a study of landownership that took place in Scania in southern Sweden in the 1860s. Basically it was a conflict between an alliance of tenant farmers and rural poor against estate owners in a time of agrarian change, a time characterized by mass evections of tenants and increasing proletarization. The participants of the movement, led by the self-taught lawyer Samuel Tullberg, claim
Popular Abstract in Swedish Organiska miljögifter finns idag i hela världen och har spridits dels genom lokala utsläpp och dels genom atmosfärisk transport. Trots att flera miljögifter (som insektsmedlet DDT och industrikemikalien PCB) har varit förbjudna sedan början av 1970-talet ser vi fortfarande höga halter av miljögifter i vår natur. Dels beror detta på att organiska miljögifter är svårnedbrAtlantic salmon (Salmo salar) from the Baltic Sea suffer from a reproduction disease known as the M74-syndrome. Newly hatched fry develop nerve disorders and die between 3-5 days after the first symptoms are seen. This is a maternally transmitted disease that is casued by a thiamine (vitamin B1) deficiency. The factor(s) that casue(s) this thiamine deficiency are largely unknown. However, several
Scatterer size estimation is useful when characterizing tissue using ultrasound. In all previous studies on scatterer size, the estimations are performed in the frequency domain and are thus subjected to a trade off in time-frequency resolution. This study focused on the feasibility of estimating scatterer size in the time domain using only the ultrasound center frequency, assuming a Gaussian-shap
