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A survey of the physiotherapy treatment methods for infants hospitalised with acute airway infections in Sweden

Purpose: The purpose of this study was to investigate what treatment methods physiotherapists in Sweden use for infants 0–24 months hospitalised with acute breathing difficulties due to lower respiratory tract infections. Material and methods: We constructed an anonymous digital survey for paediatric physiotherapists in Sweden. It was distributed by e-mail and was posted on professional websites.

Existence and coexistence of peptides in nerves of the mammalian ovary and oviduct demonstrated by immunocytochemistry

The immunocytochemical distribution of substance P (SP), gastrin releasing peptide (GRP), vasoactive intestinal polypeptide (VIP), peptide histidine isoleucine (PHI), and neuropeptide Y (NPY) was studied in the ovary and the Fallopian tube (oviduct) of rats, guinea-pigs, cows, pigs and humans. Generally, the nerve supply was better developed in the oviduct than in the ovary. GRP fibers were most s

Lipidomic profiles, lipid trajectories and clinical biomarkers in female elite endurance athletes

We assessed whether blood lipid metabolites and their changes associate with various cardiometabolic, endocrine, bone- and energy-related comorbidities of Relative Energy Deficiency in Sport (RED-S) in female elite endurance athletes. Thirty-eight Scandinavian female elite athletes underwent a day-long exercise test. Five blood samples were obtained during the day - at fasting state and before and

Incidence of cardiac interventions and associated cardiac arrest outcomes in patients with nonshockable initial rhythms and no ST elevation post resuscitation

Background: Out of Hospital Cardiac arrest (OHCA) survivors with ST elevation (STE) with or without shockable rhythms often benefit from coronary angiography (CAG) and, if indicated, percutaneous coronary intervention (PCI). However, the benefits of CAG and PCI in OHCA survivors with nonshockable rhythms (PEA/asystole) and no STE are debated. Methods: Using the International Cardiac Arrest Registr

White matter hyperintensity burden in acute stroke patients differs by ischemic stroke subtype

ObjectiveTo examine etiologic stroke subtypes and vascular risk factor profiles and their association with white matter hyperintensity (WMH) burden in patients hospitalized for acute ischemic stroke (AIS).MethodsFor the MRI Genetics Interface Exploration (MRI-GENIE) study, we systematically assembled brain imaging and phenotypic data for 3,301 patients with AIS. All cases underwent standardized we

Assessment of look-alike, sound-alike and read-alike (Lasara) medicine – Errors in pharmacy

Objective: To estimate chances of potential look-alike, sound-alike and read-alike (LASARA) errors in secondary-care hospital pharmacies through prescriptions screening. Design: Cross-sectional, prospective study. Place and duration of study: Al-Khidmat Hospital Pharmacy, Karachi, Pakistan from August to October, 2016. Methodology: Dispensed medicine data was collected from three pharmacies of a s

Association Between Estrogen Receptors and GATA3 in Bladder Cancer : A Systematic Review and Meta-Analysis of Their Clinicopathological Significance

Background: Estrogen receptors alpha (ERα) and beta (ERβ) and the cooperating protein GATA-binding factor 3 (GATA3) have been implicated in bladder carcinogenesis and tumour progression. GATA3 and ER have been functionally linked in the establishment of luminal fate in breast tissue, but to date their relationship in bladder cancer has not been established. This information will be useful to advan

Extended Follow-up of Local Steroid Injection for Carpal Tunnel Syndrome : A Randomized Clinical Trial

Importance: Local steroid injection is commonly used in treating patients with idiopathic carpal tunnel syndrome, but evidence regarding long-term efficacy is lacking. Objective: To assess the long-term treatment effects of local steroid injection for carpal tunnel syndrome. Design, Setting, and Participants: This exploratory 5-year extended follow-up of a double-blind, placebo-controlled randomiz

Sustaining the Public’s Positive Feelings towards Ungulates at the Local Level

In Europe, spatial distributions and densities of ungulates have been increasing, triggering both negative and positive feelings. Ecosystem-based and collaborative approaches to wildlife management have been introduced to, among other things, consider the perspectives of the local public. Consequently, it becomes necessary to understand the public’s emotional appraisals and feelings toward the pre

A Head-to-Head Comparison Between Plasma pTau181 and Tau PET Along the Alzheimer’s Disease Continuum

Both plasma tau phosphorylated at threonine-181 (pTau181) and tau PET show potential for detecting Alzheimer’s disease (AD) pathology and predicting clinical progression. In this study, we performed a head-to-head comparison between plasma pTau181 and tau PET along the AD continuum. Methods: We included participants from the Amsterdam Dementia Cohort who underwent 18F-flortaucipir (tau) PET and ha

Testosterone Levels in People Taking Regular Low-Dose Sustained-Release Morphine for Persisting Breathlessness : An Exploratory Study

Background: The intermediate- and long-term effects of regular low-dose sustained-release (SR) morphine on the testosterone levels of people with persistent breathlessness are unknown. Methods: Exploratory analysis of a randomized controlled trial of the effects of regular SR morphine (0/8/16/24 mg every 24 hours) for persistent breathlessness associated with chronic obstructive pulmonary disease.

Wrist osteoarthritis - Impact on daily life, self-management and outcome

For individuals with symptomatic wrist osteoarthritis (OA), pain is the central problem negatively affecting all aspects of life. Despite the recommendations that all OA patients should be offered self-management treatment options, this approach is often lacking for patients with wrist OA. In addition, there has been surprisingly little interest shown in investigating wrist OA patients' wishes and

Adverse events during endovascular treatment of ruptured aneurysms : A prospective nationwide study on subarachnoid hemorrhage in Sweden

Introduction: A range of adverse events (AEs) may occur in patients with subarachnoid hemorrhage (SAH). Endovascular treatment is commonly used to prevent aneurysm re-rupture. Research question: The aim of this study was to identify AEs related to endovascular treatment, analyze risk factors for AEs and how AEs affect patient outcome. Material and methods: Patients with aneurysmal SAH admitted to

Bivalirudin Versus Heparin During PCI in NSTEMI : Individual Patient Data Meta-Analysis of Large Randomized Trials

BACKGROUND: The benefit:risk profile of bivalirudin versus heparin anticoagulation in patients with non-ST-segment-elevation myocardial infarction undergoing percutaneous coronary intervention (PCI) is uncertain. Study-level meta-analyses lack granularity to provide conclusive answers. We sought to compare the outcomes of bivalirudin and heparin in patients with non-ST-segment-elevation myocardial

A novel interpretable deep learning model for diagnosis in emergency department dyspnoea patients based on complete data from an entire health care system

Background Dyspnoea is one of the emergency department’s (ED) most common and deadly chief complaints, but frequently misdiagnosed and mistreated. We aimed to design a diagnostic decision support which classifies dyspnoeic ED visits into acute heart failure (AHF), exacerbation of chronic obstructive pulmonary disease (eCOPD), pneumonia and “other diagnoses” by using deep learning and complete, uns