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For individuals with symptomatic wrist osteoarthritis (OA), pain is the central problem negatively affecting all aspects of life. Despite the recommendations that all OA patients should be offered self-management treatment options, this approach is often lacking for patients with wrist OA. In addition, there has been surprisingly little interest shown in investigating wrist OA patients' wishes and
This report is the result of a joint research project between Lund University and Copenhagen Business School, mainly financed by the Öresund University. The main research question was: Can the Öresund region position itself as a leading logistics centre in Scandinavia, in the light of the new conditions that the bridge brings? The purpose was to create a fundamental understanding of the new logist
BACKGROUND: The benefit:risk profile of bivalirudin versus heparin anticoagulation in patients with non-ST-segment-elevation myocardial infarction undergoing percutaneous coronary intervention (PCI) is uncertain. Study-level meta-analyses lack granularity to provide conclusive answers. We sought to compare the outcomes of bivalirudin and heparin in patients with non-ST-segment-elevation myocardial
Background Dyspnoea is one of the emergency department’s (ED) most common and deadly chief complaints, but frequently misdiagnosed and mistreated. We aimed to design a diagnostic decision support which classifies dyspnoeic ED visits into acute heart failure (AHF), exacerbation of chronic obstructive pulmonary disease (eCOPD), pneumonia and “other diagnoses” by using deep learning and complete, uns
This chapter is a gendered critique of the tenure track (TT) model in Trinity College Dublin (TCD), the oldest and most prestigious university in Ireland, with a record of fast-paced change in gender representation since 2012. The methodology includes a documentary analysis augmented with qualitative data from TT appointees. All of those interviewed who had completed the TT process obtained tenure
Two studies were conducted to assess the Swedish version of the Five Facets Mindfulness Questionnaire (FFMQ) originally created by Baer et al. (2006). The aim of Study 1 was to examine the psychometric properties of the FFMQ using data from 498 individuals. Quantitative and qualitative analyses resulted in a reduction of the scale by ten items. Psychometric properties, including internal consisten
Hydrothermal pretreatment was applied to wood sawdust, Trakya lignite and wood sawdust-Trakya lignite mixture (50%, wt) individually. Changes in fuel properties and thermochemical conversion characteristics of each were observed. In addition, the synergistic effect of biomass on coal with hydrothermal pretreatment of the mixture was investigated. After hydrothermal pretreatment, where the opti
One of the aims of PhD students’ socialisation is for them to accept the norms of the teaching culture and to be fully engaged with and accepted by the university teaching community. However, when PhD students enter universities, they do not necessarily accept all of the university teaching community’s cultural norms, nor do they all experience acceptance by the community. This phenomenographic st
Background: To date, studies investigating the association between pre-biologic biomarker levels and post-biologic outcomes have been limited to single biomarkers and assessment of biologic efficacy from structured clinical trials. Aim: To elucidate the associations of pre-biologic individual biomarker levels or their combinations with pre-to-post biologic changes in asthma outcomes in real-life.
Aims: To evaluate the cost-effectiveness of bimekizumab, an inhibitor of IL-17F and IL-17A, against biologic and targeted synthetic disease-modifying antirheumatic drugs (DMARD) for psoriatic arthritis (PsA) from the Swedish healthcare system perspective. Materials and methods: A Markov model was developed to simulate the clinical pathway of biologic [b] DMARD-naïve or tumor necrosis factor inhibi
Background: Sedation is often provided to resuscitated out-of-hospital cardiac arrest (OHCA) patients to tolerate post-cardiac arrest care, including temperature management. However, the evidence of benefit or harm from routinely administered deep sedation after cardiac arrest is limited. The aim of this trial is to investigate the effects of continuous deep sedation compared to minimal sedation o
Importance: Understanding the relationship between patients' clinical characteristics and outcomes is fundamental to medicine. When critically ill patients die after withdrawal of life-sustaining therapy (WLST), the inability to observe the potential for recovery with continued aggressive care could bias future clinical decisions and research. Objective: To quantify the frequency with which expert
This investigation analysis the depiction of jews, in swedish textbooks in primary schools, during the period 1900 to 1972, in order to determine if the depictions are antisemitic. The study uses a qualitative text analysis to analyse the source material and, based upon Helen Feins definition of antisemitism, the study determines if descriptions of jews are antisemitic. The study reveals that de
In a microbial fuel cell (MFC), exoelectrogens, which transfer electrons to the electrode, have been regarded as a key factor for electricity generation. In this study, U-tube MFC and plating methods were used to isolate exoelectrogens from the anode of an MFC. Disparate microorganisms were identified depending on isolation methods, despite the use of an identical source. Denaturing gel gradient e
Apolipoprotein M (apoM), a 25 kDa plasma protein, is found in all major lipoprotein classes, although the majority is found in high density lipoproteins (HDL). ApoM has been suggested to be involved in the formation of and adding to the antiatherogenic functions of HDL, but its function is still not completely known. ApoM has been suggested to be a lipokalin. By studies in vitro using recombinant
The most expensive component in a conventional solar photovoltaic (PV) system is the solar module cell. The module cost could be reduced if low-cost reflector materials are used to concentrate solar energy flux across a small module area. Three reflector materials were studied for fill-factor improvements in low concentrating system. These were anodized aluminium, rolled aluminium foil and miro re
Breast cancer is the most common cancer in women living in Sweden and the second most common cancer in the rest of the world. The risk of developing breast cancer is modified by environment, lifestyle, genetics and a combination of these factors. In this thesis work the combination of lifestyle and genetic polymorphisms on tumor characteristics and early recurrence have been studied. Absence of th
Background Clinical egg allergy is a common food allergy. Current management relies upon strict allergen avoidance. Oral immunotherapy (OIT) might be an optional treatment, through desensitization to egg allergen. Objectives We aimed to assess the successful desensitization and development of tolerance to egg protein and the safety of egg oral and sublingual immunotherapy in children and adults wi
In this paper we present a systematic study of the morphology and composition of supported lipid bilayers (SLBs) formed by vesicle fusion using a wide variety of surface sensitive techniques that give information about the lateral as well as vertical structure and bilayer fluidity. SLBs of 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC) and 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC
A detailed investigation of aluminum plasma induced by a 1064 nm Nd:YAG laser in air was performed. The emission of spectral lines arising from Al I transition at 396.07 nm, Al II transition at 358.46 nm, Al Ill transition at 360.72 nm and Al IV transition at 363.05 nm were well-resolved. The plasma parameters including electron temperature and electron density were determined through the Boltzman
