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Randomised double-blind placebo-controlled study of interferon -1a in relapsing/remitting multiple sclerosis

Background Previous trials of interferon in multiple sclerosis (MS) have shown efficacy, but the degree of clinical benefit remains uncertain, and the optimum dose is not known. We undertook a double-blind, placebo-controlled study in relapsing/remitting MS to investigate the effects of subcutaneous interferon -1a. Methods 560 patients with Kurtzke expanded disability status scale (EDSS) scores of

Sensitization and cross-reactivity patterns of contact allergy to diisocyanates and corresponding amines : Investigation of diphenylmethane-4,4'-diisocyanate, diphenylmethane-4,4'-diamine, dicyclohexylmethane-4,4'-diisocyanate, and dicylohexylmethane-4,4'-diamine

Background: Isocyanates are used in polyurethane production. Dermal exposure to isocyanates can induce contact allergy. The most common isocyanate is diphenylmethane diisocyanate used for industrial purposes. The isomer diphenylmethane-4,4'-diisocyanate (4,4'-MDI) is used in patch testing. Diphenylmethane-4,4'-diamine (4,4'-MDA) is its corresponding amine. Concurrent reactions to 4,4'-MDI and 4,4'

The tyranny of the averages and the indiscriminate use of risk factors in public health : The case of coronary heart disease

Modern medicine is overwhelmed by a plethora of both established risk factors and novel biomarkers for diseases. The majority of this information is expressed by probabilistic measures of association such as the odds ratio (OR) obtained by calculating differences in average "risk" between exposed and unexposed groups. However, recent research demonstrates that even ORs of considerable magnitude ar

Low serum conditions for in vitro generation of human macrophages with macrophage colony stimulating factor

Animal serum is often used to generate human macrophages in vitro. Since fetal calf serum (FCS) may complicate antigen uptake, processing and presentation on HLA molecules, we tested the ability of M-CSF to generate macrophages at low fetal calf serum conditions. Peripheral blood monocytes from 12 individuals were cultured 1-4 days with 0-100 ng/ml macrophage colony stimulating factor (M-CSF) at e

Validating the existence of the supercraton Vaalbara in the Mesoarchaean to Palaeoproterozoic

Det är allmänt känt att kontinenter under Jordens historia har separerat och kolliderat i ett cykliskt förlopp vilket har lett till existensen av större landmassor, superkontinenter eller superkratoner under vissa tidsperioder. En av de tidigaste föreslagna superkratonerna är Vaalbara, som sedan 1960-talet har ansetts bestå av Kaapvaalkratonen i södra Afrika och Pilbarakratonen i västra AustralienIn this thesis, the longevity and continuity of the Vaalbara supercraton is addressed in six papers aimed at placing new temporal and spatial constraints onthe supercraton in the Mesoarchean to Paleoproterozoic. It has been speculated since the 1960’s that the Kaapvaal Craton in southern Africa, together withthe Pilbara Craton in Western Australia existed as a single landmass during the Precambria

Three-year data from 5 HARMONY phase 3 clinical trials of albiglutide in type 2 diabetes mellitus : Long-term efficacy with or without rescue therapy

Aims Diabetes therapies that provide durable glycaemic control for people with type 2 diabetes mellitus (T2DM) are needed. We present efficacy results of albiglutide, a glucagon-like peptide-1 receptor agonist, in people with T2DM over a 3-year period. Methods Five of the 8 HARMONY phase 3 trials, comparing albiglutide with other therapies or placebo across a spectrum of clinical care, lasted for

Is a hollow centralizer necessary when using a polished, tapered, cemented femoral stem? : A randomized, controlled RSA study of 60 hips with 10 years of follow-up

Background and purpose — A tapered, polished and collarless stem is normally equipped with a hollow centralizer to prevent the stem from becoming end-bearing in the cement as the stem subsides. In a randomized clinical trial, we evaluated such a stem (MS-30), which was initially introduced with a solid centralizer but was later recommended to be fitted with a hollow centralizer. We hypothesized th

A new simplified electrocardiographic score predicts clinical outcome in patients treated with CRT

Aims Cardiac Resynchronization Therapy (CRT) reduces morbidity and mortality for patients with heart failure and wide QRS complex, but up to 1/3 of patients are "non-responders" to the therapy. This study examines the ability of a simple standard electrocardiogram (ECG)-based scoring system to predict clinical outcome. Methods and results Four hundred and ninety-one consecutive patients with CRT

A new silurian ophiuroid from the west of Ireland

Silurian echinoderms from Ireland are poorly known; hitherto, only three nominal species have been described, all crinoids and all from the Telychian (Upper Llandovery, Lower Silurian) Kilbride Formation in County Galway. A new species from this formation, Crepidosoma doylei, is the first recorded Irish Silurian ophiuroid (brittle star). The new species is described from five articulated specimens

Prevalence of faecal ESBL carriage in the community and in a hospital setting in a county of Southern Sweden.

The aim of this study was to investigate the prevalence of extended-spectrum beta-lactamase (ESBL)-producing bacteria in patients at various hospital wards and in a group of relatively healthy volunteers, in order to obtain greater knowledge on how common these bacterial strains are in hospital settings and in the general community. Participants (n = 427) were enrolled at a University Hospital and

Patient advocacy: barriers and facilitators

BACKGROUND: During the two recent decades, advocacy has been a topic of much debate in the nursing profession. Although advocacy has embraced a crucial role for nurses, its extent is often limited in practice. While a variety of studies have been generated all over the world, barriers and facilitators in the patient advocacy have not been completely identified. This article presents the findings o

Could the increased use of e-bikes (pedelecs) in Sweden contribute to a more sustainable transport system?

The transport sector accounts for large proportions of greenhouse gas emissions and energy usage in Sweden, about 40% and 30%, respectively. Most of this, 93%, comes from road transports. There is, therefore, a strong political desire to reduce the use of fossil fuels in road transport. Several alternatives to fossil fuels have been discussed and, more recently, interest in electrically driven veh

The functional variant V433M of the CYP4F2 and the metabolic syndrome in Swedes.

BACKGROUND AND AIM: The genetic basis of Metabolic syndrome (MetS) is largely unknown but a link with salt sensitivity is recognized. The cytochrome P450 isoform 4F2 (CYP4F2) is involved in renal production of 20-hydroxyeicosatethraenoic acid (20-HETE), a natriuretic substance associated with salt sensitivity. The same enzyme is implicated in ω-hydroxylation of very long and medium chain fatty aci

Scoring models of a diet quality index and the predictive capability of mortality in a population-based cohort of Swedish men and women.

OBJECTIVE: To examine how different scoring models for a diet quality index influence associations with mortality outcomes. DESIGN: A study within the Malmö Diet and Cancer cohort. Food and nutrient intakes were estimated using a diet history method. The index included six components: SFA, PUFA, fish and shellfish, fibre, fruit and vegetables, and sucrose. Component scores were assigned using pre

Projecting streamflow in the Tangwang River basin (China) using a rainfall generator and two hydrological models

To estimate the impacts of future climate change on streamflow in the Tangwang River basin (TRB) in northeastern China, 2 hydrological models, the Soil and Water Assessment Tool and the Hydro-Informatic Modeling System, were used. These models are driven by future (2021-2050) local rainfall and temperature scenarios downscaled from global climate model (GCM) simulations from the fifth phase of the

General syllabus for third cycle studies in film and media 150603

Brevmall Reg. no U2015/183 Facul ty o f F ine and Performing Ar ts , Malmö General Syllabus for Third Cycle Studies in Film and Media leading to a Degree of Doctor of Philosophy in Fine Arts 1. Programme details Programme and specialisation: Third cycle studies in Film and Media Code: KOFIME00 Credits: 240 Cycle: Third Degree title in English: Doctor of Philosophy in Fine Arts in Film and Media De

https://www.arts.lu.se/sites/arts.lu.se/files/general_syllabus_for_third_cycle_studies_in_film_and_media_150603.pdf - 2026-05-06

Qmod 2014 final program with welcome 20140819 1

4th September 2013, Wednesday 17th QMOD-ICQSS Conference 3rd-5th September, 2014 Prague, Czech Republic Program Jointly organized by: Lund University, Linköping University & University of Economics, VŠE, Prague Welcome Address from the Founders of QMOD-ICQSS It is our great pleasure to welcome you to the 17th QMOD-ICQSS conference, the conference which has become one of the largest scientific conf

https://www.ses.lu.se/en/sites/ses.lu.se.en/files/qmod_2014_final_program_with_welcome_20140819_1.pdf - 2026-05-06

Anhorig-form baseline

Stora anhörigformuläret Frågeformulär Till Dig som hjälper/vårdar en person i hemmet GÅS Gott åldrande i Skåne Till Dig som hjälper närstående Vi ber Dig fylla i bifogade frågeformulär och vänligen besvara samtliga frågor. All information som lämnas är sekretessbelagd och all presentation av data kommer att ske så att ingen enskild person kan identifieras. Så här fyller Du i frågeformuläret: De f

https://www.geriatrik.lu.se/sites/geriatrik.lu.se/files/anhorig-form_baseline.pdf - 2026-05-06

Budget 2017 konstnarliga fakulteten pdf 0

BUDGET 2017 LUNDS UNIVERSITET | KONSTNÄRLIGA FAKULTETEN Sammanställning Hamidullah Turab, Kansli K Grafisk form Jessica Arwidsson, Kansli K LUNDS UNIVERSITET Konstnärliga fakulteten Dnr STYR 2016/1452 Resursfördelning för utbildning på grund- och avancerad nivå samt för forskning och forskarutbildning verksamhetsåret 2017. Institutionerna inom den konstnärliga fakulteten skall för 2017 göra en tot

https://www.konstnarliga.lu.se/sites/konstnarliga.lu.se/files/budget_2017_konstnarliga_fakulteten_pdf_0.pdf - 2026-05-06