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Assessment of quality of care provided to adults with type 2 diabetes mellitus at public hospitals in Gamo Gofa zone, Southern Ethiopia : Facility based Cross-Sectional study

PURPOSE: Proactive management of type 2 diabetes is important for restoring beta-cell function and improving sustained blood glucose control. Evidence on quality of diabetes care in Ethiopia is inadequate.METHOD: Facility-based cross-sectional study was conducted to assess level of quality of care provided to adult type 2 diabetes patients at three public hospitals in Gamo Gofa Zone, Southern Ethi

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Objectives:To assess the effectiveness of smoking cessation programs implemented during pregnancy and to assess the impact of these programs on the health of the fetus and infant, on the mother and on the family. Search strategy: Randomized and quasi-randomized controlled trials indentified by the search strategy of the Cochrane Pregnancy and Childbirth Group, supplemented by the search strategy o

Treatment With Reduced-Dose Trimethoprim-Sulfamethoxazole Is Effective in Mild to Moderate Pneumocystis jirovecii Pneumonia in Patients With Hematologic Malignancies

BACKGROUND: Recent studies have reported that reduced-dose trimethoprim-sulfamethoxazole (TMP-SMX) may be effective in the treatment of Pneumocystis jirovecii pneumonia (PJP), but data are lacking for patients with hematologic malignancies.METHODS: This retrospective study included all adult hematologic patients with PJP between 2013 and 2017 at 6 Swedish university hospitals. Treatment with 7.5-1

Comparison of four clinical risk scores in comatose patients after out-of-hospital cardiac arrest

Background and aims: Several different scoring systems for early risk stratification after out-of-hospital cardiac arrest have been developed, but few have been validated in large datasets. The aim of the present study was to compare the well-validated Out-of-hospital Cardiac Arrest (OHCA) and Cardiac Arrest Hospital Prognosis (CAHP)-scores to the less complex MIRACLE2- and Target Temperature Mana

Spatial Navigation and Its Association with Biomarkers and Future Dementia in Memory Clinic Patients Without Dementia

Background and ObjectivesImpaired spatial navigation is considered an early sign in many neurodegenerative diseases. We aimed to determine whether spatial navigation was associated with future dementia in patients with subjective cognitive decline (SCD) or mild cognitive impairment (MCI) and to explore associations between spatial navigation and biomarkers of Alzheimer disease (AD) and neurodegene

Merging dual-polarization X-band radar network intelligence for improved microscale observation of summer rainfall in south Sweden

Compact dual-polarization doppler X-band weather radars (X-WRs) have recently gained attention in Scandinavia for sub-km and minute scale rainfall observations. This study develops a method for merging data from two X-WRs in Dalby and Helsingborg, southern Sweden (operated at five and one elevation angle levels, respectively) to improve the accuracy of rainfall observations. In total, 87 rainfall

Studies of the ABO and FORS Histo-Blood Group Systems: Focus on Flow Cytometric and Genetic Analysis

ABO is the clinically most important blood group system and its antigens are carbohydrate moieties present on the surface of the red blood cell (RBC) but also on other tissues throughout the body. The ABO gene encodes an enzyme, a glycosyltransferase (GT),that adds a terminal monosaccharide to the precursor structure, H antigen, to define the A or B antigens. Blood group O is due to a non-function

Predictors of response to methotrexate in early DMARD naive rheumatoid arthritis: results from the initial open-label phase of the SWEFOT trial

Objective To identify predictors of response to methotrexate (MTX) in early rheumatoid arthritis (RA). Methods In the SWEFOT trial, patients with RA with symptom duration <1 year started MTX monotherapy (20 mg/weekly) and 405/487 continued until the 3-4-month visit. The primary outcome measure was the DAS28-based European League against Rheumatism (EULAR) response criteria. Multivariate logistic r

Clonal diversity and allozyme variation in populations of the arctic sedge Carex bigelowii (Cyperaceae).

1 A study of allozyme variation in vegetatively propagating populations of the rhizomatous sedge Carex bigelowii, revealed high levels of clonal diversity (genet diversity) within populations. The structure of allelic variation within the populations suggests that sexual reproduction has played a significant role in these C. bigelowii populations, despite present lack of seedling recruitment. The

Midterm results of laser generated in situ fenestration of the left subclavian artery during thoracic endovascular aneurysm repair

Objective: To analyze the midterm result of in situ fenestration (ISF) of the left subclavian artery (LSA) during thoracic endovascular aneurysm repair (TEVAR). Methods: In this clinical study, between 2014 and 2016, ISF for LSA revascularization was attempted during TEVAR in 10 patients (7 males; median age, 68 years). An excimer laser, placed from the left brachial artery, was used to create a f

Risk of Soft-Tissue Sarcoma Among 69 460 Five-Year Survivors of Childhood Cancer in Europe

Background: Childhood cancer survivors are at risk of subsequent primary soft-tissue sarcomas (STS), but the risks of specific STS histological subtypes are unknown. We quantified the risk of STS histological subtypes after specific types of childhood cancer.Methods: We pooled data from 13 European cohorts, yielding a cohort of 69 460 five-year survivors of childhood cancer. Standardized incidence

Depression in type 1 diabetes was associated with high levels of circulating galectin-3

Objective: Neuroinflammatory responses are implicated in depression. The aim was to explore whether depression in patients with type 1 diabetes (T1D) was associated with high circulating galectin-3, controlling for metabolic variables, s-creatinine, life style factors, medication, and cardiovascular complications.Design: Cross-sectional.Methods: Participants were T1D patients (n=283, 56% men, age

90-Day readmission after radical prostatectomy—a prospective comparison between robot-assisted and open surgery

Purpose: All types of surgery are associated with complications. The debate is ongoing whether robot-assisted radical prostatectomy can lower this risk compared to open surgery. The objective of the present study was to evaluate post-operative adverse events leading to readmissions, using clinical records to classify these adverse events systematically. Materials and methods: A prospective control

Assessment of lactate production as a response to sustained intrapartum hypoxia in large-for-gestational-age newborns.

Introduction Lactate concentration in umbilical cord blood is an important measure of intrapartum anaerobic metabolism. The aim of the study was to compare lactate production of large‐for‐gestational‐age (LGA) fetuses against appropriate‐for‐gestational‐age (AGA) fetuses during hypoxia, in diabetic and non‐diabetic mothers. Material and methods A total of 17 358 validated paired arterial and ven

Clonal chromosome aberrations are present in vivo in synovia and osteophytes from patients with osteoarthritis

We have previously reported recurrent clonal chromosomal aberrations in synovia, osteophytes and articular cartilage from patients with osteoarthritis (OA). In particular, gain of chromosomes 5 and 7 was found to be strongly associated with OA. In order to exclude the possibility of in vitro artefacts, we studied three to four parallel, independent cultures from ten samples of synovia and three sa

Children's practice of computer-based composition

Today’s children live in a world where music in all its different forms has become a significant factor in their everyday life. This article describes a 2-year empirical study of nine 8-year-old Swedish children creating music with synthesiser and computer software. The aim of the study is to describe and clarify the creative processes of computer-based composition. The tasks given to the children

Sociolinguistic, comparative and historical perspectives on Scandinavian gender: With focus on Jamtlandic

The present thesis investigates gender assignment in Jamtlandic from a sociolinguistic and historical/comparative perspective. Jamtlandic is a language variety spoken in northwestern Sweden in the province of Jämtland. It maintains a three-gender system, in contrast to Standard Swedish, which has a two-gender system. Study 1 of the thesis looks at Jamtlandic gender assignment from a sociolinguisti