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Late-Onset Hypogonadism and Mortality in Aging Men

Context: Late-onset hypogonadism (LOH) has recently been defined as a syndrome in middle-aged and elderly men reporting sexual symptoms in the presence of low T. The natural history of LOH, especially its relationship to mortality, is currently unknown. Objective: The aim of this study was to clarify the associations between LOH, low T, and sexual symptoms with mortality in men. Design, Setting, a

From sign to action : studies in chimpanzee pictorial competence. : Studies in chimpanzee pictorial competence

Many studies of children and apes realized in psychology address issues that are highly relevant to semiotics, but they often do so indirectly, or they use a terminology that is confusing and/or too vague from a semiotical point of view. The studies reported here, however, follow the paradigm of these psychological studies, but they are couched in an explicit semiotical terminology. They involve t

Hodgkin lymphoma after autoimmune diseases by age at diagnosis and histological subtype

Increased risk of Hodgkin lymphoma (HL) associated with personal history of several autoimmune diseases (ADs), such as rheumatoid arthritis, systemic lupus erythematosus, sarcoidosis, and immune thrombocytopenic purpura, are known. Whether there are other HL-related ADs and whether the increased risk of HL after ADs holds across sex, age, year of diagnosis, or HL histological subtype is unclear. W

Urologic disease in a resource-poor country

BACKGROUND: Understanding the role that urologic disease plays within central Haiti could lead to the development of sustainable and regionally appropriate urologic care. We aim to document the prevalence of urologic surgical disease presenting for treatment in central Haiti. METHODS: The present study is based on a retrospective review of surgical case logs at five Partners in Health and Zanmi La

Presynaptic calcium signalling in cerebellar mossy fibres

Whole-cell recordings were obtained from mossy fibre terminals in adult turtles in order to characterize the basic membrane properties. Calcium imaging of presynaptic calcium signals was carried out in order to analyse calcium dynamics and presynaptic GABA B inhibition. A tetrodotoxin (TTX)-sensitive fast Na+ spike faithfully followed repetitive depolarizing pulses with little change in spike dura

Adverse Reactions after Vaccination and Allergen-Specific Immunotherapy: Contact Allergy to Aluminium and Itching Nodules

Popular Abstract in Swedish Oönskade reaktioner efter vaccination och allergenspecifik immunoterapi - Kontaktallergi för aluminium och kliande knutor För att ett vaccinationsprogram ska fungera krävs kontinuerlig uppföljning av vaccinernas säkerhet vad gäller eventuella oönskade reaktioner. Under de senaste 10 till 15 åren har en ökad oro noterats bland allmänhet och profession beträffande oönskadThe aim of the work presented in this thesis was to investigate two different types of adverse reactions, persistent itching nodules and contact allergy to aluminium, after immunization with aluminium-containing vaccines and aluminium-containing allergen extracts used for allergen-specific immunotherapy (ASIT). The first paper describes active parental reporting of adverse events (AEFIs) after a

Expression of innate immunity genes and damage of primary human pancreatic islets by epidemic strains of echovirus: implication for post-virus islet autoimmunity.

Three large-scale Echovirus (E) epidemics (E4,E16,E30), each differently associated to the acute development of diabetes related autoantibodies, have been documented in Cuba. The prevalence of islet cell autoantibodies was moderate during the E4 epidemic but high in the E16 and E30 epidemic. The aim of this study was to evaluate the effect of epidemic strains of echovirus on beta-cell lysis, beta-

Social capital, the miniaturisation of community and consumption of homemade liquor and smuggled liquor during the past year.

Background: To study the impact of social participation, trust and the miniaturisation of community, i.e. high social participation/low trust, on consumption of homemade liquor and smuggled liquor during the past year. Methods: The Scania 2000 public health survey is a cross-sectional, postal questionnaire study. A total of 13,604 persons aged 18–80 years were included. A logistic regression model

In situ hydrogen loading on zirconium powder

For the first time, various hydride phases in a zirconium-hydrogen system have been prepared in a high-energy synchrotron X-ray radiation beamline and their transformation behaviour has been studied in situ. First, the formation and dissolution of hydrides in commercially pure zirconium powder were monitored in real time during hydrogenation and dehydrogenation, then whole pattern crystal structur

Pollen production estimates (PPEs) and fall speeds for major tree taxa and relevant source areas of pollen (RSAP) in Changbai Mountain, northeastern China

For model-based quantitative reconstructions of past vegetation cover on the scale of landscapes, pollen productivity estimates (PPEs) are key input parameters. In this study, we employed a random sampling strategy to collect moss polsters at 20 sites in Changbai Mountain, northeastern China. A detailed vegetation survey within 1000-m radius around each sampling point was carried out and digitized

Electronic structure and chemical bonding in W-2 molecule

The electronic structure of the lowest-lying electronic states of W-2 were investigated at the CASPT2 level. The ground state is a X-1 Sigma(+)(g) state, followed by the a(3)Delta(u), b(3)Sigma(+)(u) and A(1)Delta(u) electronic states. Seven low-lying Omega-states were computed: (1)0(g)(+), (2)3(u), (3)2(u), (4)1(u), (5)0(u)(-), (6)1(u), and (7)2(u), with the ground state corresponding to the (1)0

Tumor location and patient characteristics of colon and rectal adenocarcinomas in relation to survival and TNM classes

Background: Old age at diagnosis is associated with poor survival in colorectal cancer (CRC) for unknown reasons. Recent data show that colonoscopy is efficient in preventing left-sided cancers only. We examine the association of Tumor Node Metastasis (TNM) classes with diagnostic age and patient characteristics. Methods: The Swedish Family-Cancer Database has data on TNM classes on 6,105 CRC aden

Social Inequalities and Mortality in Europe - Results from a Large Multi-National Cohort

Background: Socio-economic inequalities in mortality are observed at the country level in both North America and Europe. The purpose of this work is to investigate the contribution of specific risk factors to social inequalities in cause-specific mortality using a large multi-country cohort of Europeans. Methods: A total of 3,456,689 person/years follow-up of the European Prospective Investigation

Pulse Wave Velocity Measurements by Magnetic Resonance Imaging in Neonates and Adolescents : Methodological Aspects and Their Clinical Implications

Pulse wave velocity (PWV) by cardiovascular magnetic resonance (CMR) lacks standardization. The aim of this study was to investigate methodological aspects of PWV measurements by CMR in neonates and adolescents. A computer phantom was created to validate the temporal resolution required for accurate PWV. Fifteen neonates and 71 adolescents underwent CMR with reference standard 3D angiography and p

Outcomes After Acute Coronary Syndrome in Patients With Diabetes Mellitus and Peripheral Artery Disease (from the TRACER, TRILOGY-ACS, APPRAISE-2, and PLATO Clinical Trials)

Patients with acute coronary syndrome (ACS) are at risk for recurrent adverse events, and multiple reports suggest that this risk is increased in patients with concomitant diabetes mellitus (DM) and peripheral artery disease (PAD). The aim of this article was to investigate cardiovascular outcomes in patients with DM presenting with ACS, stratified by PAD status. Data were derived from 4 randomize

Physical Activity in Late Prepuberty and Early Puberty Is Associated With High Bone Formation and Low Bone Resorption

Background: Physical activity (PA) increases bone mass, especially in late prepuberty and early puberty, but it remains unclear if and how PA affects both bone formation and bone resorption. Materials and Methods: We included 191 boys and 158 girls aged 7.7 ± 0.6 (mean ± SD) in a population-based PA intervention study. The intervention group (123 boys and 94 girls) received daily physical educatio

Associations between physical frailty and living arrangements in Japanese older adults living in a rural remote island : The Shimane CoHRE study

Background: Living arrangements have been known to be associated with physical frailty. However, the prevalence of frailty and its risk factors in remote islands is not understood. We examined the association between living arrangements and objectively measured frailty among older adults living in a remote island of Japan. Methods: Among older people living in Okinoshima, 656 older adults (75.6 ±

Scheimpflug lidar range profiling of bee activity patterns and spatial distributions

Background: Recent declines of honeybees and simplifications of wild bee communities, at least partly attributed to changes of agricultural landscapes, have worried both the public and the scientific community. To understand how wild and managed bees respond to landscape structure it is essential to investigate their spatial use of foraging habitats. However, such studies are challenging since the