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Prognostic factors in squamous cell carcinoma of the head and neck, with emphasis on 11q13 rearrangements and cyclin D1 overexpression.

Popular Abstract in Swedish Populärvetenskaplig sammanfattning Skivepitelcancer i huvud- och halsregionen (SCCHN) Kliniska aspekter Prognosen vid SCCHN är i stort sett oförändrat dålig sedan 30 år tillbaka; cirka hälften av patienterna dör av sin sjukdom. Trots stora tekniska framsteg kring behandlingsteknikerna (ofta en kombination av kirurgi, strål- och i viss mån cellgiftsbehandling) medför dAt present, clinical outcome or response to therapy can not be fully predicted in individual cases of squamous cell carcinoma of the head and neck (SCCHN). The overall aim of the present studies was to investigate potential prognostic factors, more closely related to the malignant progression of a tumor than the established markers, such as the TNM-classification system. Tumor samples were investi

Law and reform in Morocco

Morocco has for twenty years been in what is officially described as a transition to democracy. During the former king Hassan II negotiations with the opposition resulted in two constitutional reforms and a new government in 1998 dominated by the former opposition parties. In the 2000s two important law reforms were made: a new law of personal status in 2004 and a new constitution in 2011. The new

Evaluation of seven different enzyme-linked immunosorbent assays for serodiagnosis of Staphylococcus aureus bacteremia

Objective: Serologic assays for Staphylococcus aureus antibodies were evaluated regarding their ability to differentiate between uncomplicated and complicated S. aureus bacteremia, between S. aureus and non-S. aureus bacteremia, and between S. aureus and non-S. aureus endocarditis. Methods: Enzyme-linked immunosorbent assays (ELISAs) were performed to measure Ig G antibodies against seven S. altre

Contamination of polyethylene cups with polymethyl methacrylate particles: an experimental study

The articulating surfaces of 6 ultra-high molecular weight polyethylene cups were exposed to curing polymethyl methacrylate (PMMA) bone-cement and examined with scanning electron microscopy and laser ablation inductively coupled plasma mass spectrometry (LA-ICPMS). Three of the cups were exposed to blood and bone-cement, and the rest were exposed to bone-cement only. After removal of the bone-ceme

Perceived participation in life situations in persons with late effects of polio

Objective: To investigate how persons with late effects of polio perceive their participation and problems with participation in life situations and to determine the association between perceived problems with participation and sex, age, marital status, use of mobility aids and access to instrumental support. Design: Cross-sectional. Subjects: A total of 160 persons with prior polio 6-30 months af

Hur har coronapandemin påverkat byggbranschens verksamhet?

Bakgrund: Världshälsoorganisationen, WHO, deklarerade Covid-19 som en pandemi den 11 mars 2020. Viruset satte snabbt sina spår på byggbranschen och det ledde till vidtagna åtgärder. Lösningen som gick efter folkhälsomyndighetens centralt styrda restriktioner handlar framförallt om att undvika fysisk kontakt och skapa en säker och god fysisk miljö för arbetarna. För att säkerställa en god arbetsmilBackground: The World Health Organization, WHO, declared Covid-19 a pandemic on March 11, 2020. The virus quickly left its mark on the construction industry and this led to measures taken. The solution that followed the public health authority's restrictions is above all, avoiding physical contact and creating a safe environment for the employees. To ensure a functionate environment, the const

Polynomial Computer Algebra and implementation of Wilf-Zeilberger's method

The purpose of the thesis is to get a better understanding of computer algebra in general, and polynomial computer algebra in particular. This is done by implementing a library for a polynomials and methods that are needed to be able to perform operations on the polynomials. Then this library is used to implement Wilf-Zeilberger’s method, which is a method that can be used to prove certain combina

Rädda eller låta dö? En idéanalys av en riksdagsdebatt om SAAB-krisen

The following thesis studies a debate around the economic hardships for SAAB Automobile AB in particular as well as for the entire Swedish automobile industry in general. The debate took place in the Swedish parliament, the 20th of March 2009. The purpose with this study is to investigate which ideological bases the participants of the debate were grounding their statements upon. The study also i

Co-evolution of the HIV-1 R5 phenotype and the viral envelope glycoproteins

To gain entry into target cells, HIV-1 binds to CD4 via the viral glycoprotein gp120. This interac-tion initiates a series of events including binding of a coreceptor, CCR5 and/or CXCR4, and ulti-mately leads to gp41-mediated fusion of the viral and cell membranes. CCR5-restricted (R5) vi-ruses predominate in early, asymptomatic stages of the infection. Emergence of viruses able to use CXCR4 inste

Hjälp och stöd? - föräldrar till barn med Aspergers syndrom

Our purpose with this essay was to examine and compare the help, that children with Asperger’s syndrome and their parents receive and have received from the Swedish welfarestate. The question we asked were: · From the parents point of view, what do they and their children need help with? · Which help have they received? We decided to divide our study into two time-periods, the time before and the

Invandrarmammors sociala nätverk

The purpose of this study was to investigate how immigrant mothers in Sweden view their social network and how they think their social network affects their parenthood. The study is based on a qualitative method. We interviewed eight immigrant women with children under the age of 18. During the interviews we used maps of networks in order to get a clearer picture of the size and the structure of t

Treatment outcome in T-cell lymphoblastic lymphoma in adults - a population-based study from the Swedish Lymphoma Registry

Background. T-cell lymphoblastic lymphoma (T-LBL) is a rare neoplasm of precursor lymphoblast origin, for which there is no standard treatment for adults. Results of current treatment strategies in selected populations do exist but are largely unreported for unselected series. Here, we aimed to investigate treatment outcome in a population-based cohort. Material and methods. Patients were identifi

CdTe@Cu(OH)(2) nanocomposite: Aqueous synthesis and characterization

CdTe@Cu(OH)(2) nanocomposites were synthesized in aqueous solution by a seed-mediated growth approach. The effect of refluxing time and the concentration of Cu2+ on the preparation of these samples were measured using UV-visible absorption and photoluminescence analysis. The emission peak of the synthesized nanocomposites (CdTe@Cu(OH)(2)) was shifted from 605 (CdTe seed) to 621 nm. The size of CdT

Upper gastrointestinal trauma. Analysis of 45 cases of gastric, duodenal or pancreatic injury

Injuries to the upper gastrointestinal tract occurring over a 30-year period in a geographically well defined region were analyzed. The incidence was low in comparison with other abdominal injuries, but duodenal and pancreatic injuries were increasingly common in the study's last decade. The stomach injuries were mainly caused by penetrating trauma. The duodenal and pancreatic injuries most common

Bioinspired covalently grafted Cu(II)-C protected amino acid complexes: selective catalysts in the epoxidation of cyclohexene

In this work, the syntheses of covalently grafted C-protected Cu(II)-amino acid (methylesters of l-histidine and l-cystine) uniform and mixed ligand complexes with two different amino acid esters are described using chloropropylated silica gel as the support. The conditions of the syntheses were systematically altered. The structural features of the substances obtained were studied by the Kjeldahl

No association of COMT val158met polymorphism and psychotic symptoms in Lewy body dementias

We sought to determine whether the COMT val158met polymorphism (rs4680) is associated with delusions and hallucinations in people with dementia with Lewy bodies (DLB) and Parkinson's disease dementia (PDD). A total of 218 individuals, recruited from centres in Norway, Sweden and the UK were included in this study; 121 with clinically or neuropathologically diagnosed DLB/PDD and 97 age-matched, cog

Determination of amylose content in different starches using modulated differential scanning calorimetry

A simple calorimetric method for determination of amylose content in starch is reported. Starches were heated in the presence of two common surfactants, viz., sodium dodecyl sulphate (SDS) and cetyltrimethylammonium bromide (CTAB), and the enthalpies of melting of the amylose-surfactant complexes were determined using Modulated Differential Scanning Calorimetry (MDSC). A large number of native sta