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Intervention thresholds for osteoporosis in men and women: a study based on data from Sweden

The aim of this study was to determine the threshold of fracture probability at which interventions became cost-effective in men and women, based on data from Sweden. We modeled the effects of a treatment costing $500 per year given for 5 years that decreased the risk of all osteoporotic fractures by 35% followed by a waning of effect for a further 5 years. Sensitivity analyses included a range of

Further insight in the web consolidation process - Part III. Modelling of paper shrinkage

A model for the web consolidation process in the paper dryer is developed and compared with experimental data for the kraft pulps. The model contains one parameter called the shrinkage factor which is used as the fitting parameter to the experimental data. The shrinkage factor can have a value between zero implying no shrinkage and a value of one which implies that all the liquid volume removed le

Gastrointestinal symptoms and psychological well-being in patients with microscopic colitis.

Abstract Objective. Microscopic colitis (MC) and irritable bowel syndrome (IBS) are both gastrointestinal disorders with female predominance that affect well-being. Autoantibodies against gonadotropin-releasing hormone (GnRH) have recently been detected in IBS patients. The purpose of this study was to compare gastrointestinal symptoms and well-being in MC female outpatients, with or without coexi

A comparison between flexible electrogoniometers, inclinometers and three-dimensional video analysis system for recording neck movement

This study compared neck range of movement recording using three different methods goniometers (EGM), inclinometers (INC) and a three-dimensional video analysis system (IMG) in simultaneous and synchronized data collection. Twelve females performed neck flexion-extension, lateral flexion, rotation and circumduction. The differences between EGM, INC, and IMG were calculated sample by sample. For fl

Turbulence and combustion interaction: High resolution local flame front structure visualization using simultaneous single-shot PLIF imaging of CH, OH, and CH2O in a piloted premixed jet flame

High resolution planar laser-induced fluorescence (PLIF) was applied to investigate the local flame front structures of turbulent premixed methane/air jet flames in order to reveal details about turbulence and flame interaction. The targeted turbulent flames were generated on a specially designed coaxial jet burner, in which low speed stoichiometric gas mixture was fed through the outer large tube

Factors Associated with Multiple Medication Use in Different Age Groups

BACKGROUND: Multiple medicine use among elderly persons is likely to be the result of treatment regimens developed over a long period of time. By learning more about how multiple medication use develops, the quality of prescribing may be improved across the adult lifespan. OBJECTIVE: To describe patterns of multiple medicine use in the general Swedish population and its association with sociodemog

The mode of school transportation in pre-pubertal children does not influence the accrual of bone mineral or the gain in bone size - two year prospective data from the paediatric osteoporosis preventive (POP) study

Background: Walking and cycling to school are one source of regular physical activity. The aim of this two years observational study in pre-pubertal children was to evaluate if walking and cycling to school was associated with higher total amount of physical activity and larger gain in bone mineral content (BMC) and bone width than when going by car or bus. Methods: 133 boys and 99 girls aged 7-9

Living with cancer and perception of care: Icelandic oncology outpatients, a qualitative study

Aim This qualitative study was set out to explore oncology outpatient experiences of having cancer, to illuminate coping strategies and to explore perceptions of care and service provided while treated for cancer. Materials and methods Thirty patients undergoing chemotherapy or radiotherapy were consecutively selected for the study in three oncology outpatient clinics in Iceland; mean age was 55 y

Incident investigations by the regulatory authority of Swedish healthcare - a 20-year perspective

Objective: The purpose of this study was to describe procedural changes in hospital incident investigations and show the consequences of these changes over time. Methods: A two-stage method was used. First component of the study was a content analysis of 87 incident investigations conducted 1995-2014 by the regulatory authority after adverse events in a Swedish university hospital. Second compone

Sequence Analysis of the Capsid Gene during a Genotype II.4 Dominated Norovirus Season in One University Hospital: Identification of Possible Transmission Routes.

Norovirus (NoV) is a leading cause of gastroenteritis and genotype II.4 (GII.4) is responsible for the majority of nosocomial NoV infections. Our objective was to examine whether sequencing of the capsid gene might be a useful tool for the hospital outbreak investigation to define possible transmission routes. All NoV positive samples submitted from one university hospital during the 2007/8 season

Impact on allergic immune response after treatment with vitamin A

Background: Vitamin A may have some influence on the immune system, but the role in allergy modulation is still unclear. Objective: To clarify whether high levels of retinoic acid (RA) affects allergic response in vivo, we used a murine experimental model of airway allergic disease. Methods: Ovalbumin (OVA)-immunization/OVA-challenge (OVA/OVA) and house dust mite (HDM)-immunization/HDM-challenge (

Detection of intracavitary uterine pathology using offline analysis of three-dimensional ultrasound volumes: interobserver agreement and diagnostic accuracy

Objective To estimate the diagnostic accuracy and interobserver agreement in predicting intracavitary uterine pathology at offline analysis of three-dimensional (3D) ultrasound volumes of the uterus. Methods 3D volumes (unenhanced ultrasound and gel infusion sonography with and without power Doppler, i.e. four volumes per patient) of 75 women presenting with abnormal uterine bleeding at a bleeding

Algal MIPs, high diversity and conserved motifs

Background: Major intrinsic proteins (MIPs) also named aquaporins form channels facilitating the passive transport of water and other small polar molecules across membranes. MIPs are particularly abundant and diverse in terrestrial plants but little is known about their evolutionary history. In an attempt to investigate the origin of the plant MIP subfamilies, genomes of chlorophyte algae, the sis

Evaluation of a treatment protocol in distal radius fractures: a prospective study in 581 patients using DASH as outcome.

BACKGROUND AND PURPOSE: Distal radius fractures are most often treated nonoperatively, but sometimes they are treated surgically when deemed unstable. Based on the literature, a consensus protocol for treatment has been developed in southern Sweden to aid clinicians in their decision making. We evaluated the results of this protocol prospectively using a validated outcome instrument (DASH) in a la

TGF-B signaling in Neuroblastoma and Renal Cell Carcinoma

The tubular cells of the adult kidney are normally mitotically quiescent, in stark contrast to the massive regenerative capacity of the injured renal epithelium. In Paper I we characterized a new cell population of progenitor cells using ALDH as a selection marker. These cells are situated in the proximal tubular epithelium and are called proximal tubular progenitor cells (PTPCs). Gene expression

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This thesis, “Die Wiedergabe der Wirklichkeit” (“The Reported Reality”), explores from a contrastive perspective what linguistic strategies serious German and Swedish newspapers use in different text genres as they report from reality. Two German – die Frankfurter Allgemeine Zeitung and die Süddeutsche Zeitung – and two Swedish newspapers – Dagens Nyheter and Svenska Dagbladet – are studied. For e

Structure-property correlations of ion-containing polymers for fuel cell applications

In order to investigate the structure-property correlations of grafted proton conducting membranes, the model system consisting of an ETFE base film grafted with polystyrene and subsequent sulfonation (ETFE-g-PSSA) along with crosslinked derivatives ETFE-g-P(SSA-co-DiPB) were synthesized. The characteristics of the final membranes were characterized by PFG-NMR diffusometry, in-plane conductivity a

BRCA2 germ-line mutations are frequent in male breast cancer patients without a family history of the disease

Breast cancer is a rare disease in men, affecting less than 0.1% of the male population. Two heritable gene defects have been associated with a predisposition to male breast cancer development, ie., germ-line mutations in the breast cancer susceptibility gene BRCA2 and the androgen receptor (AR) gene. In this study, the entire coding regions of BRCA2 and AR were screened for mutations in 34 consec