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Objective To compare the genetic regulation of collagen-induced arthritis (CIA) with that of pristane-induced arthritis (PIA) in rats. Methods A genome-wide linkage analysis of an (E3 × DA)DA backcross of rats with CIA (n = 364 male rats; the same strain combinations as previously used to determine the genetic control of PIA) was performed. The strongest loci in both CIA and PIA (i.e., Cia12/Pia4
Large-scale studies are essential to assess the emission patterns and spatial distribution of organohalogenated pollutants (OHPs) in the environment. Bird eggs have several advantages compared to other environmental media which have previously been used to map the distribution of OHPs. In this study, large-scale geographical variation in the occurrence of OHPs, such as polychlorinated biphenyls (P
Adult neurons possess the ability to adapt to a changing environment. Loss of target-derived neurotrophic factors due to axotomy or isolation by culturing is known to induce changes in neuropeptide expression in several types of peripheral neurons. The aim of the present study was to investigate changes in the expression of vasoactive intestinal polypeptide (VIP) and nitric oxide synthase (NOS) in
Background: The haem-binding protein alpha(1)-microglobulin (alpha(1)m) is involved in protection against oxidative damage induced by extracellular haem/haemoglobin. A carboxy-terminally truncated form of alpha(1)m (t-alpha(1)m), formed by reactions with haemoglobin, degrades haem into a yellow-brown chromophore linked to the protein. The aim of this work was to investigate if t-alpha(1) in is pre
Background: The frequencies with which physicians make different medical end-of-life decisions (ELDs) may differ between countries, but comparison between countries has been difficult owing to the use of dissimilar research methods. Methods: A written questionnaire was sent to a random sample of physicians from 9 specialties in 6 European countries and Australia to investigate possible differences
The objective of present work was to determine and compare the components of bioaerosol in several sectors of plant processing industries. The Study was conducted in 10 Facilities engaged in herb and grain processing, flax threshing, grain storing, baking, and cereals production. The air samples were taken on glass fibre litters with an AS-50 sampler. We determined the concentrations of airborne m
Popular Abstract in Swedish Ett system där flera personer och maskiner kan kommunicera samtidigt över ett gemensam medium kallas ett fleranvändarsystem. Den här avhandlingen presenterar och analyserar olika fleranvändarsystem där mediet består av en radiokanal med hög bandbredd. Analyser av hur många användare som kan kommunicera samtidigt och olika sätt för att öka denna kapacitet är presenterad.Wideband CDMA (Code Division Multiple Access) is one of the key technologies for future mobile communication systems. This thesis studies various coding and transmission methods for wideband CDMA communications. In a cellular environment, the system performance depends on the interference from other cells. An analysis of the other-cell interference in the forward link, from the base station to the
Popular Abstract in Swedish Nanotrådar har potential att bli en mycket flexibel plattform för design av halvledarkomponenter. I nanotrådar är det möjligt att bilda kristallstrukturer som normalt sett inte förekommer i bulkmaterial, och att kombinera olika III-V och grupp IV material i axiella eller radiella heterostrukturer. Eftersom så pass komplicerade strukturer kan skapas, både avsiktligt och Nanowires have the potential to be a very flexible platform for the design of semiconductor devices. In nanowires it is possible to form crystal structures not found in the bulk materials under normal conditions, and to combine different III-V and group IV materials into axial or radial heterostructures. As quite complex structures can be formed, both intentionally and unintentionally, characteriz
The aim of this chapter is to move the issue a bit beyond the polarized views of profound critical reflection versus excessive trust in the checking procedures behind standards. We claim that the polarized views are largely due to an over-simplistic understanding of transparency. By comparing practical policy processes surrounding various standards, we aim to provide nuance to the issue of transpa
The pains Macrocarpaea (Griseb.) Gilg (Gentianaceae. Helieae) is among the largest woody genera of tropical gentians, with most of its species occurring in the wet mountainous forest., of the Andes. Phylogenetic and dispersal-vicariance analyses (DIVA) of 57 of the 105 currently recognized species in the genus. Using two data sets front nuclear DNA (ITS and 5S-NTS sequences) and morphology. show i
Musculoskeletal disorders are very common and affects the individual by pain and functional impairment, and the society through work disability and healthcare utilisation. To what extent is less studied. Routinely collected healthcare registers is a potential resource for epidemiological studies of musculoskeletal disorders. Skåne region, as opposed to nationally in Sweden, has healthcare register
Segmentation is an important task in all kinds of image analysis. In medical image analysis segmentation has a great clinical value since the aim could be to localize organs or pathologies in order to raise the quality of diagnoses. This thesis consists of three papers where different segmentation techniques have been applied to different imaging modalities. In the first paper a full computer assi
Background: Optimal manual closed chest compressions are difficult to give. A mechanical compression/ decompression device, named LUCAS, is programmed to give compression according to the latest international guidelines (2005) for cardiopulmonary resuscitation (CPR). The aim of the present study was to compare manual CPR with LUCAS-CPR. Methods: 30 kg pigs were anesthetized and intubated. After a
Background: Prior studies have identified some risk factors for stress fracture in athletes and military recruits. Objective: To determine whether historical factors, physical measures, biochemical variables of skeletal metabolism, genetic factors, bone density (BMD) and bone size could predict risk of stress fracture over 4 years in physically fit cadets at the US Military Academy (USMA). Methods
The critical levels for ozone effects on vegetation have been reviewed and revised by the LRTAP Convention. Eight new or revised critical levels based on the accumulated stomatal flux of ozone (POD gamma, the Phytotoxic Ozone Dose above a threshold flux of Y nmol m(-2) PLA s(-1), where PLA is the projected leaf area) have been agreed. For each receptor, data were combined from experiments conducte
Telavancin is a novel bactericidal lipoglycopeptide with multiple mechanisms of action against gram-positive pathogens. The aim of this study was to describe the dynamics of the antimicrobial effect of telavancin against two strains of Staphylococcus aureus (methicillin susceptible and methicillin resistant) in an in vitro kinetic model with simulated human pharmacokinetics. Also, static experimen
Background: Non-linearities in observed log-ratios of gene expressions, also known as intensity dependent log-ratios, can often be accounted for by global biases in the two channels being compared. Any step in a microarray process may introduce such offsets and in this article we study the biases introduced by the microarray scanner and the image analysis software. Results: By scanning the same sp
The Fra a I allergen in strawberry (Fragaria ananassa) is homologous to the major birch pollen allergen Bet v 1, which has numerous isoforms differing in terms of amino acid sequence and immunological impact. To map the extent of sequence differences in the Fra a I allergen, PCR cloning and sequencing was applied. Several genomic sequences of Fra a 1, with a length of either 584, 591 or 594 nucleo
