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The influence of tool steel microstructure on friction in sheet metal forming

The frictional behavior of a number of conventional tool materials used in the sheet forming industry has been studied by a recently developed tribotester based on flat-die strip drawing. The main objective was to study the frictional performance of the materials and correlate the tribological behavior mainly to the microstructure. Tooling materials tested ranged from powder metallurgical tool ste

Bioinformatic strategies for unambiguous identification of prostate specific antigen in clinical samples

Prostate specific antigen (PSA), as a widely used clinical biomarker in prostate cancer diagnostics, exists in multiple molecular forms. However, all of these forms might not be recognized in a given sample by the standard immunoassays. Therefore, we have investigated PSA isoforms separated by size using mass spectrometric analyses. The objective of these developments was to identify and specify t

High activity of xylose reductase and xylitol dehydrogenase improves xylose fermentation by recombinant Saccharomyces cerevisiae

Xylose fermentation performance was studied of a previously developed Saccharomyces cerevisiae strain TMB 3057, carrying high xylose reductase (XR) and xylitol dehydrogenase (XDH) activity, overexpressed non-oxidative pentose phosphate pathway (PPP) and deletion of the aldose reductase gene GRE3. The fermentation performance of TMB 3057 was significantly improved by increased ethanol production an

Trisomies in Hematologic Malignancies

Acquired clonal chromosome aberrations, closely associated with leukemogenesis, are found in many hematologic malignancies. Although the balanced rearrangements, such as translocations and inversions, are the ones most commonly thought of in the context of leukemias, gains of chromosomes ? e.g.., trisomies ? are also frequent. Little is known about the biologic outcome, the pathogenetic significan

α-l-FucosyItransferases in Human Serum from Donors of Different ABO, Secretor and Lewis Blood-Group Phenotypes

The presence of α-l-fucosyltransferases in human serum of different ABO, secretor and Lewis blood-group phenotypes was investigated with guanosine diphosphate fucose as the sugar donor and low-molecular-weight oligosaccharides, or a macromolecular glycoprotein, as acceptors. In contrast to the α-2-l-fucosyltransferases in human milk, submaxillary glands and stomach mucosa that occur only in ABH se

Corneal surface changes in keratoconjunctivitis sicca. Part II: the mucus component. A non-contact photomicrographic in vivo study in the human cornea

Purpose Description of mucus on the corneal surface and in the precorneal tear film in keratoconjunctivitis sicca (KCS). Methods In all, 24 patients with KCS examined with slit lamp and by non-contact photomicrography. Results Material interpreted as mucus seemed to exist in three varieties: one optically dense, light reflecting, and with definite forms ( fine threads, variously thick and long str

Identification of a novel calreticulin isoform (Crt2) in human and mouse

Calreticulin is a Ca2+-binding chaperone localized mainly in the endoplasmic/sarcoplasmic reticulum in all higher organisms. To date, only one calreticulin isoform has been identified in human and mouse. Here we report a novel calreticulin isoform (Crt2) in human and mouse, with 53 (human) and 49% (mouse) identity to the previously identified calreticulin in respective species. The gene encoding t

Konversion och konfession – om konversionsliknande övergångar hos Henric Schartau och F. G. Hedberg i relation till en andra konfessionaliseringsperiod

Conversion and Confession – Religious Transitions similar to Conversion in Henric Schartau and F. G. Hedberg, related to a Second Confessional Age The nineteenth century has often been called an Age of Secularisation. This has been criticized as blindness of religion. The »long» nineteenth century meant a mobilization of religion. German Historian Olaf Blaschke has interpreted the period as a sec

Palliative care training: a survey of physicians in Australia and Europe

The purpose of this paper is to present data about the level and background characteristics of physicians' training in palliative care in Australia (AU), Belgium (BE), Denmark (DK), Italy (IT), the Netherlands (NL), Sweden (SE) and Switzerland (CH) (n=16,486). The response rate to an anonymous questionnaire differed between countries (39%-68%). In most countries approximately half of all respondin

Selenoprotein P. Nutritional and clinical aspects

In this thesis, the nutritional regulation and clinical significance of selenoprotein P (SeP) in human plasma of healthy and diseased subjects was investigated. For the analysis of SeP, a radioimmunoassay was developed using polyclonal antibodies. The epitope recognized by the antibodies was apparently stable after storage of plasma in the frozen state for years. In the studies included, the coeff

Evaluating the discriminative power of multi-trait genetic risk scores for type 2 diabetes in a northern Swedish population

We determined whether single nucleotide polymorphisms (SNPs) previously associated with diabetogenic traits improve the discriminative power of a type 2 diabetes genetic risk score. Participants (n = 2,751) were genotyped for 73 SNPs previously associated with type 2 diabetes, fasting glucose/insulin concentrations, obesity or lipid levels, from which five genetic risk scores (one for each of the

Clustering of concordant and discordant cancer types in Swedish couples is rare

Background: Spouses are exposed to common environmental cancer risk factors during adulthood. Investigating the aggregation of cancer in couples might provide valuable insights into cancer development. Methods: The 2008 update of the Swedish Family-Cancer Database includes over 2 million couples with at least one child in common with one single partner. We quantified the contribution of shared adu

Ordbetoning och ordbetydelse i rumänska.

Popular Abstract in Swedish Denna avhandling är en dokumentation av mina undersökningar av det rumänska ordet. Jag har som allmänlingvist undersökt några aspekter av det rumänska ordet fonologiskt, fonetiskt och semantiskt. Det finns också mycket skrivet om morfologin i rumänska. Man är väl medveten om att en del suffix tar betoning och andra inte. Men ingen har utnyttjat denna kunskap för att sysThe book is divided into three parts. All three parts dealwith the Romanian word. Part A: Word stress has not been defined in one rule before. I show how one rule can be applied to nouns, verbs and countnouns of Romanian. The principal method is taken from lexical phonology. Part B: Part A gave me the idea to investigate phonological length in the forms of infinitive, 3sg imperfect and perfect. An

COPD and the risk of tuberculosis--a population-based cohort study.

BACKGROUND: Both chronic obstructive pulmonary disease (COPD) and tuberculosis (TB) primarily affect the lungs and are major causes of morbidity and mortality worldwide. COPD and TB have common risk factors such as smoking, low socioeconomic status and dysregulation of host defence functions. COPD is a prevalent co-morbid condition, especially in elderly with TB but in contrast to other diseases k

Cesarean section scar defects: agreement between transvaginal sonographic findings with and without saline contrast enhancement.

OBJECTIVES: To determine the agreement between transvaginal ultrasound examinations performed before and at saline contrast sonohysterography (SCSH) with regard to number, size and shape of Cesarean section (CS) scar defects. METHODS: In all, 108 women underwent transvaginal ultrasound examination with SCSH at least 6 months after CS: 68 had undergone one CS, 32 two CSs and eight women had undergo

Orthostatic Hypotension Predicts Incidence of Heart Failure: The Malmö Preventive Project.

BackgroundThe presence of orthostatic hypotension (OH) predicts all-cause mortality and incident cardiovascular disease. Whether or not OH is associated with the development of heart failure (HF) remains unknown.MethodsIn this Swedish population-based prospective study (the Malmö Preventive Project), the incidence of HF in relation to baseline OH, defined as decrease in systolic (SBP) >/=20 mm Hg

Software deployment activities and challenges – an industrial case study of four software product companies

Abstract in UndeterminedSoftware deployment, including both clean installs and updates, is a crucial activity for all software vendors. It starts with a customer's order of a new release and incorporates all steps taken until the customer is satisfied with the deployed product. Using interviews as the main data collection method, we conducted a case study of four companies to discover their softwa