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Alzheimers sjukdom är den vanligaste orsaken till demens och omkring 100 000 svenskar beräknas lida av sjukdomen. Runt om i världen beräknas ungefär 50 miljoner människor lida av Alzheimers sjukdom. En peptid som är inblandad i sjukdomen är Amyloidβ som kan vara olika lång beroende på vilka APP-sekretas som klyver Amyloid-βproteinprekursor. I den här studien har de peptider med 40 (Amyloidβ40), re

I Sverige finns det ingen lagstadgad skyldighet att bistå nödställda personer. Undantag finns i vissa situationer när det framgår av lag eller allmänna principer. Att se på när en okänd människa drunknar utan att hjälpa till, trots att personens liv enkelt kan räddas är idag straffritt. Syftet med denna uppsats är att med hjälp av en rättsdogmatisk metod utreda om en civilkuragelag bör införas i SIn Sweden there is no statutory duty to rescue distressed persons. Exceptions can be made when this is required by a special law or by legal principles, but watching an unknown person drown when his life easily can be saved is not illegal. The purpose of this essay is to, by using a traditional judicial method, examine whether this behaviour should be criminalized or not. If the duty to rescue di

Barn och föräldrars värderingar, underlag för lösningen på ett växande trafik- och samhällsproblem? Resultat från LTH:s nya examensarbete om barns säkra och trygga skolvägar förväntas kunna ge underlag för att minska problemen skapade genom föräldrar som skjutsar sina barn till skolan. Trafiksituationen vid många svenska skolor har beskrivits som kaosartad och skapat många frågetecken för framtidThis master thesis focuses on safe and secure routes to school and the point of departure is the phenomena that parents take their children to school by car instead of using sustainable alternatives as cycling and walking. This behavior creates a number of problems around schools as congestion and lack of traffic safety. Also the roads that are used for traveling to and from school, experience the

Abstract This thesis work was performed at RUAG Space AB, Göteborg, Sweden. The aim of this thesis is to test the performance boundaries of SiGe based heterojunction bipolar transistor in designing a low noise amplifier meant for GNSS applications. After careful consideration of different alternatives for active components in SiGe HBT process, BFY640-04 from Infineon was selected as the active com

Having a specialized editor or IDE has become commonplace for many programming languages. Smaller languages, especially domain-specific ones that normally have very narrow usage areas, often lack such convenience features due to their naturally small user base. Tools for implementing editor support for these languages are called language workbenches. Unfortunately these often lack features for mor

Background: Health care reforms introducing patient choice have been gaining popularity during the last decades and several countries have implemented patient choice. The underlying principle of patient choice is anchored in the concept of the well-informed patient, an individual that knows what he or she is choosing between. Several information sources, related to choice of caregiver and treatmen

Abstract Author: Lisa Avenius Title: Suspicion that a child is being maltreated - a study of preschool teachers views on mandatory reporting The aim of this study was to get preschool-teachers views and experiences on previously researched areas surrounding the notification tendency regarding mandatory reporting. The mandatory report contains an obligation to immediately report suspected child mal

In today’s housing market, open house plans are requested increasingly. This puts a demand on the beams being used to manage longer spans and is therefore exposed to larger loads. To manage these larger loads, one solution is to increase the beam dimensions. Because of demands to fulfill standardized measurements for doors, ceiling heights and roofing heights, there is not always room for the beam

Control of haemorrhage is vital in all operative settings. As complement to traditional surgical haemostatic techniques, a heterogeneous collection of absorbable substances with haemostatic capacity have been developed; topical haemostatic agents. The widespread variety of the products and the study-populations (clinical or experimental) make interpretation of previously performed studies difficul

Popular Abstract in Swedish SVENSK SAMMANFATTNING Den kliniska effekten av läkemedel som administreras till näsa eller lunga beror på läkemedlets egenskaper och på dess lokala deposition. Depositionsstudier är därför värdefulla för att kunna karakterisera olika beredningar. Depositionen påverkas av partiklarnas storlek och hastighet, genom att stora partiklar med hög hastighet ger upphov till en hThe local deposition, pharmacokinetics, and systemic activity of inhaled and intranasal glucocorticosteroids in different formulations and devices(ICSs) has been investigated. After nasal administration of the ICS budesonide (Bud), the systemic availability (F) was found to be significantly higher from an aqueous pump spray and from the powder inhaler Turbuhaler, than from a pressurized metered do

The presented thesis work is concerned with the study of molecular dynamics using liquid nuclear magnetic resonance (NMR) spectroscopy. Spin relaxation dispersion experiments in the rotating frame (R_1ρ) are employed to provide a detailed, atomic-resolution view of protein dynamics. Comprehensive investigations of ¹⁵N backbone and ¹³C methyl side-chain confor

Popular Abstract in Swedish Mörkerseendet är en mycket känslig nervfunktion och mycket känsligare för låg syrgastillförsel än högre mentala funktioner. Mörkerseendet är kraftigt reducerat hos patienter med två kliniskt sett så olika tillstånd som förträngd halspulsåder (carotisstenos) och "trögflytande blod" (polycytämi). Gemensamt för båda patientgrupperna är en under lång tid störd blodcirculatiPurpose: To study dark adaptation in patients with symptomatic carotid artery disease or polycythemia before and after treatment. This necessitated determinations of pupillary changes as such may influence the findings. To determine whether changes in the retinal blood flow in light and darkness occur in healthy humans. Methods: Repeated automatic dark adaptometry was recorded monocularly in 21 c

Anomaly detection is becoming a powerful and necessary component as wireless networks gain popularity. In this paper, we evaluate the efficacy of PCA based anomaly detection for wireless mesh networks (WMN). PCA based method [1] was originally developed for wired networks. Our experiments show that it is possible to detect different types of anomalies, such as Denial-of-service (DoS) attack, port

Through in-depth interviews, students’ experiences and perceptions of good teaching practice in literature and physics during one school year were investigated in eight upper secondary classes of the first, second and third years in Greece. Students’ feelings of joy, pleasure and personal meaning in the teaching and learning situation were in focus of the research. Three main and interconnected as

OBJECTIVE: Patients with non-muscle-invasive bladder cancer are traditionally followed by repeat cystoscopy and urine cytology. A fluorescence in situ hybridisation technique called UroVysion((R)) (UV) is now available for clinical diagnosis of urothelial cancer cells. The aim of the present study was to compare UV analysis with routine follow-up methods. METHODS: We studied an unselected cohort o

In this work the syntheses, structure and SOD activity of covalently grafted Fe(III)-complexes formed with various N- or C-protected amino acid ligands (L-histidine and L-tyrosine) inspired by the active site of the Fe SOD enzyme are presented. Chloropropylated silica gel was used as support to mimic the proteomic skeleton of the enzyme. Anchored complexes having uniform amino acids as well as the

Background: Synaptic degeneration is an early pathogenic event in Alzheimer's disease, associated with cognitive impairment and disease progression. Cerebrospinal fluid biomarkers reflecting synaptic integrity would be highly valuable tools to monitor synaptic degeneration directly in patients. We previously showed that synaptic proteins such as synaptotagmin and synaptosomal-associated protein 25