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Prevalence and prognostic value of electrocardiographic abnormalities in hypokalemia: A multicenter cohort study

AbstractBackgroundHypokalemia is common in hospitalized patients and associated with ECG abnormalities. The prevalence and prognostic value of ECG abnormalities in hypokalemic patients are, however, not well established.MethodsThe study was a multicentered cohort study, including all ault patients with an ECG and potassium level <4.4 mmol/L recorded at arrival to four emergency departments in Denm

Pain as bad as you can imagine or extremely severe pain? A randomized controlled trial comparing two pain scale anchors

Background: A common method of pain assessment is the numerical rating scale, where patients are asked to rate their pain on a scale from 0 to 10, where 0 is “no pain” and 10 is “pain as bad as you can imagine”. We hypothesize such language is suboptimal as it involves a test of a cognitive skill, imagination, in the assessment of symptom severity. Methods: We used a large-scale online research re

Development of boosted machine learning models for estimating daily reference evapotranspiration and comparison with empirical approaches

Proper irrigation scheduling and agricultural water management require a precise estimation of crop water requirement. In practice, reference evapotranspiration (ETo) is firstly estimated, and used further to calculate the evapotranspiration of each crop. In this study, two new coupled models were developed for estimating daily ETo. Two optimization algorithms, the shuffled frog-leaping algorithm

Autoimmune congenital heart block and primary Sjögren's syndrome : characterisation and outcomes of 49 cases

OBJECTIVES: To characterise autoimmune congenital heart block (CHB) associated with a maternal diagnosis of primary Sjögren's syndrome (pSS) confirmed either before, concomitant or after the first pregnancy complicated with CHB.METHODS: The following inclusion criteria were applied: (i) Mothers with positive Ro/La autoantibodies detected previously or at the time of diagnosis of the first case of

Falls After Stroke : A Follow-up after Ten Years in Lund Stroke Register

OBJECTIVES: To evaluate incidence of self-reported falls and associated factors in a ten-year perspective after stroke.METHODS: From a population-based cohort of first-ever stroke patients (n = 416) included in the Lund Stroke Register between March 1, 2001, and February 28, 2002, we performed a follow up of all 145 survivors ten years after stroke. We collected data on age, gender, main stroke ty

Estimation of physical performance and measurements of habitual physical activity may capture men with high risk to fall-Data from the Mr Os Sweden cohort

To evaluate if clinically usable estimates of physical performance and level of habitual physical activity are associated with fall risk in elderly men. A population-based sample of 3014 randomly selected men aged 69-80 years was recruited to medical centers in Gothenburg, Malmoe, or Uppsala. The level of physical activity and self-reported falls during the preceding 12 months was evaluated using

Recurrent Pregnancy Loss. Aspects of Epidemiology, Immunology, Treatment and Obstetric Outcomes.

Aims: Recurrent pregnancy loss (RPL), defined as three consecutive miscarriages, is a multifaceted problem whose resolution needs a broad approach. In this thesis, epidemiology, immunology, treatment and obstetrical outcomes areexplored. The aims are as follows: To establish the incidence of the diagnosis of RPL in the National Patient Register (NPR) in Sweden from 2003 to 2012 (Paper I). To evalu

Effects of cardiovascular pharmacotherapies on incident dementia in patients with atrial fibrillation : A cohort study of all patients above 45 years diagnosed with AF in hospitals in Sweden

Background: Patients with atrial fibrillation (AF) have an increased dementia risk dementia. We aimed to study the effect of antihypertensive drugs on dementia in AF patients. Methods: Included patients were ≥45 years diagnosed with AF in Swedish National Patient Register (n = 160,251; 89,723 men and 70,528 women) and alive on January 1, 2007. We excluded patients with dementia before onset of AF.

Implementing Telemedicine During the COVID-19 Pandemic: Disparities in Utilization in an Urban Pain Medicine Practice

Purpose: The COVID-19 pandemic led to a drastic expansion in utilizing telemedicine, circumventing some of the geographical barriers to accessing pain care. However, uncertainties around the impact of telemedicine across various sociodemographic groups still exist, prompting further exploration. Therefore, this study aimed to evaluate the impact of sociodemographic factors in telemedicine utilizat

Mortality not increased in patients with non-functional adrenal adenomas : a matched cohort study

CONTEXT: Mild autonomous cortisol secretion (MACS) is associated with increased mortality in patients with adrenal incidentalomas (AI), but little is known regarding the potential risk associated with non-functional adrenal adenomas (NFAA), which constitute the majority of AI.OBJECTIVE: Compare mortality risk in patients with NFAA, and different levels of MACS, to matched controls.METHOD: This was

Diagnostic value of repeated comprehensive investigation with CT urography and cystoscopy for recurrent macroscopic haematuria

Objectives: To perform a descriptive analysis of a series of patients with recurrent macroscopic haematuria after a primary standard evaluation including computed tomography urography (CTU) and cystoscopy negative for urinary bladder cancer (UBC) and upper tract urothelial cancer (UTUC) and to identify potential factors associated with occurrence of recurrent macroscopic haematuria. Methods: All p

Bivalirudin vs Heparin Anticoagulation in STEMI : Confirmation of the BRIGHT-4 Results

Background: In the BRIGHT-4 (Bivalirudin With Prolonged Full-Dose Infusion During Primary PCI Versus Heparin Trial-4), anticoagulation with bivalirudin plus a 2- to 4-hour high-dose infusion after percutaneous coronary intervention (PCI) reduced all-cause mortality and bleeding without increasing reinfarction or stent thrombosis compared with heparin alone in patients with ST-segment elevation myo

Optimization of Bacterial Strains and Development of Fermented Seaweed

This study aimed to understand the exploitation of bacterial strains used in various combinations to assist in the fermentation of seaweeds. The topic stems from the need to consider the valorization of seaweeds due to their abundance in natural habitats as well as their use as an innovative and sustainable food. Fermentation is a traditional method that has been utilized for food preservation. It

The Potential Use of Degradable Starch Microspheres as a Carrier for Nasal Drug Administration

Nasal administrering är en administeringsmetod där läkemedel inhaleras genom näsan. Metodens huvudsakliga syfte är att snabbt och effektivt behandla lokala symtom. Men på senare tid har det även ökats intresse för att uppnå en systemisk effect, där läkemedlet når blodomloppet och därigenom påverkar hela kroppen. Näshålan är ungefär 15-20 ml, med en yta på cirka 150 cm2 och är uppdelad i två symmIntranasal drug delivery is a practical and accessible method for treating localized symptoms as well as achieving systemic drug absorption. The approach takes advantage of the permeability, vascularization, and limited enzymatic activity of nasal tissue, leading to enhanced drug absorption. Moreover, drugs can bypass the blood-brain barrier and directly reach the brain through the olfactory route

Vård som inte kan anstå – En analys av begreppet i förhållande till Sveriges internationella åtaganden om hälso- och sjukvård för papperslösa

Personer som vistas i Sverige utan tillstånd, papperslösa, har enligt lag (2013:407) om hälso- och sjukvård till vissa utlänningar som vistas i Sverige utan nödvändiga tillstånd, rätt att erhålla en begränsad hälso- och sjukvård. Bland annat ska regioner erbjuda gruppen ”vård som inte kan anstå”. Begreppet har av yrkesverksamma, frivilligorganisationer och myndigheter kritiserats för att vara svårPeople staying in Sweden without permit – undocumented migrants – have, according to the Act (2013:407) on health care for certain foreigners who are staying in Sweden without necessary permits, a right to receive limited health care. Among other things, Swedish regions must offer this group “care that cannot be deferred”. This wording has been criticized by medical professionals, organizations, a

Resilience Uncovered: A review of professional resilience measurement methodologies

Recent policy developments on the global, regional and national levels have materialised strategic goals for building resilience. Implementing resilience fundamentally requires operationalising the concept in order to make it measurable. This thesis scoped for professional resilience measurement methodologies across grey literature and analysed their organisational purposes and specifics of measur

Geographical inequalities in burden of disease at local authority level in Scotland: A subnational analysis for the Scottish Burden of Disease Study 2016

Background: Scotland possesses the worst mortality outcomes and slowest improvement in life expectancy of Western Europe. Within Scotland, stark inequalities exist in both morbidity and mortality. There remains paucity in assessment of subnational variation in disease burden. Aim: This thesis explored geographical inequalities in burden of disease (BoD) across 32 Scottish authorities. Secondary an

Den rättsliga regleringen av barnaga under 1900-talet - en del i civiliseringsprocessen?

Syftet med denna uppsats är att utreda hur och varför lagstiftarens inställning till och den rättsliga regleringen av bruket av kroppsaga mot barn förändrades under 1900-talet och huruvida denna förändring kan sägas vara en följd av en civiliseringsprocess. De frågeställningar som använts är följande: hur förändrades den rättsliga regleringen av kroppsaga av barn mellan år 1900 och år 1979? Hur föThe purpose of this essay is to study how and why the legislator’s opinion on and the legal regulation of the corporal punishment of children changed during the 20th century as well as examine if it can be explained as a part of a civilizing process. The research questions are as follows: how did the legal regulation of the corporal punishment of children change between 1900 and 1979? How did the

Functional ingredients in rapeseed

Vid produktion av kallpressad rapsolja bildas en biprodukt, kallad presskaka som för närvarande säljs som djurfoder för en billig peng. Att hitta nya användningsområden för presskakan skulle därför kunna gynna svenska rapsbönder ekonomiskt. Odling av raps är den enskilt största oljefröväxten i Sverige och odlas just för att pressa rapsoljan ur fröna. Rapsoljan anses som en bra fettråvara då den inPress cake is a residual after rapeseed oil production, which is currently sold as animal feed at a relatively low price. In order to raise the value of the press cake and also to obtain non-allergenic food emulsions, it would be beneficial to extract a protein called oleosin from rapeseed. These proteins have been found to have good emulsifying properties. Unlike other sources of emulsifying agen