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OBJECTIVE: To monitor changes in family physicians' reported practice on hypertension and hypercholesterolaemia. DESIGN: Random samples of physicians were selected for telephone interviews on their practice regarding cut-off levels and pharmacological treatment of hypertension and hypercholesterolaemia, related to a case scenario of a 48-year-old man, in 1989, 1991 and 1993. SETTING: Primary care
Purpose Randomized clinical trials can provide strong evidence regarding effective treatment options. The quality of reporting and the type of outcome measures used are important when judging whether results justify change in clinical practice. The aim of this study was to assess the quality of reporting of randomized clinical trials related to treatment of upper-extremity disorders, published in
This population-based register study examined if factors during the fetal and neonatal period influence the risk for the child to develop bronchial asthma (asthma). From the Swedish Hospital Discharge Register we identified children, born between 1987 and 1999, who had been hospitalized for asthma up to 2001. Thus, the outcome measure contains only hospitalized cases, not all children with asthma.
OBJECTIVE: To explore the feasibility of prospectively monitoring treatment efficacy and tolerability of infliximab, etanercept, and leflunomide over a two year period in patients with established rheumatoid arthritis (RA) in clinical practice using a structured protocol. METHODS: All patients with RA at seven centres in southern Sweden, for whom at least two disease modifying antirheumatic drugs,
Pigs of the same genetic type at the RN and HAL loci, i.e. rn(+) RN-/NN were reared in similar conditions of feeding and housing. They were slaughtered in two abattoirs (referred to as A1 and A2) using a mixture of air (30%) and CO2 (70%), at a rate of 300 pigs per hour per slaughterline. One hundred and thirty-two pigs from I I farms were slaughtered in A I using a corusinga restrainer and 127 pi
Background: Studies during the 1990s showed that it was possible to reduce the rate of negative appendectomies by using various diagnostic methods. The present study aims to evaluate the effect on diagnostic accuracy of implementation of repeated clinical examination and blood tests in a small county hospital without possibilities of radiological assistance on a 24-hour basis. Methodology: Prospec
Objective: To identify the reasons and their relative importance why medicines are returned to Swedish pharmacies unused. Setting: A random sample of the pharmacies in Sweden. Method: Interviews using a semi-structered interview form with pharmacy customers returning unused medicines to the pharmacy. Main outcome measure: Reasons given by patients/relatives/carers for returning unused medicines to
Calcium phosphate materials (CaPs) have proven biocompatible and useful in clinical situations. One CaP showing promise in the clinic is alpha phase tricalcium phosphate ([alpha]-TCP). [alpha]-TCP in powder form can be hydrated and undergoes a reaction resulting in calcium deficient hydroxyapatite (CDHA). The similarity of CDHA and human bone makes [alpha]-TCP a very viable material for applicatio
In the male moth, Agrotis ipsilon, the neuronal basis for juvenile hormone (JH)-linked modulation of sex pheromone responsiveness was investigated following stimulation of the antenna with i) an extract of female pheromone gland, ii) the synthetic pheromone blends from A. ipsilon and a closely related species, A. segetum, and iii) single components of the A. ipsilon blend. Response characteristics
OBJECTIVE: To assess prevalence figures for psychiatric disorders among institutionalized adolescents due to behavioural problems and/or delinquency. METHOD: Participants were recruited from consecutive referrals to/or treated at two Swedish adolescent units, SIS1 (n = 60) and SIS2 (n = 70) with ranging age of 12-20.3 years (mean age = 16.2; SD = 1.8) during 1 year. Clinical and diagnostic info
Background. An altered renal function is an essential component of the patho-physiology of pre-eclampsia. The plasma levels of low molecular mass proteins, e. g. beta-trace protein, beta-2-microglobulin and cystatin C, are increased in the third trimester of normal pregnancy. The plasma levels of cystatin C and beta-2-microglobulin are further increased in preeclampsia, and the cystatin C level ha
A chemiluminescence inummoassay for the detection of four heart marker proteins: myoglobin, creatine kinase mb [CKmb], troponin I [Tnl], and fatty acid-binding protein [FABP], was designed. The inummoassay was based on enzyme-linked immunosorbent assay [ELISA] and antibodies immobilized in glass capillaries pre-treated with 3-aminopropyltriethoxysilane. The protein bound to the antibody was detect
"Lethal midline granuloma" of the upper airways generally encompasses T-cell lymphoma and Wegener's granulomatosis in Western populations. Treatment and outcome for each is different, but their pathological distinction may not always be possible on routine biopsy specimens. Within a defined population between 1947 and 1994, we found 12 cases of primary sinonasal T-cell lymphoma, all with a CD20-,
This study aimed to evaluate the association between objectively measured habitual physical activity and calcaneal and forearm bone mineral density (BMD, g/cm(2)), one mechanically more loaded and one less loaded skeletal region, in children aged 6-8 years. BMD was measured in 297 boys and 265 girls by peripheral dual-energy X-ray absorptiometry in the forearm and calcaneus. An accelerometer regis
It is widely accepted that alkaline phosphatase activity (APA) is an efficient indicator of phosphate limitation in freshwater phytoplankton communities. In this study, we investigated whether the response in APA to phosphate limitation differs among the taxa in a mixed phytoplankton assemblage. We used the new enzyme-labeled fluorescence (ELF) technique, which allows microscopic detection of phos
After time-consuming and costly investigations, patients with neck metastases from an occult primary often receive unnecessarily large radiation volumes to treat a possible origin in the nasopharynx. In this study a colorimetric antisense Epstein-Barr early ribonucleoprotein 1 (EBER1) oligonucleotide probe specific for Epstein-Barr virus RNA was hybridized in situ to metastatic tissue obtained fro
The modeling of industrial combustion applications today is almost exclusively based on two-equation turbulence models. Despite its known limitations, the most the widely used model is still the standard k-ε model. The objective of this paper is to investigate the performance of two-equation turbulence models applied to a confined swirling flow. Numerical modeling of an axis-symmetric confined sud
The pathologic mechanisms of chronic obstructive pulmonary disease (COPD) most certainly involves neutrophil granulocytes, cytotoxic T-cells, macophages and mast cells. The aim of this study was to investigate the relation between the number of mast cells in different compartments in bronchial biopsies of central proximal airways to structural changes, lung function tests and emphysema detected by
Describing the biotic and abiotic processes that are responsible for the formation of spatial patterns in predators and their prey is crucial for improving our understanding of food-web interactions. We studied the spatial distribution of four abundant spider species and three common groups of epedaphic Collembola prey in a beech-dominated (Fagus sylvatica) forest floor habitat and related the obs
