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Antipsychotics - Postmortem fatal and non-fatal reference concentrations

Making the diagnosis fatal intoxication is a challenging task for the forensic pathologist and toxicologist, particularly when the cases involve substances where reference information is scarce or not at all available. This study presents postmortem femoral blood concentrations for 24 antipsychotic substances, based on samples collected and analyzed from 4949 autopsy cases in Sweden during 1992-20

Two-dimensional imaging of glyoxal (C2H2O2) in acetylene flames using laser-induced fluorescence

Laser-induced fluorescence measurements have been performed in turbulent non-premixed flames close to the lift-off point and in laminar premixed acetylene flames. The spectrally analyzed fluorescence signal showed good correspondence to known spectra from glyoxal (C2H2O2). Laser-induced fluorescence spectra from glyoxal vapor using the same excitation wavelength of 428 nm showed the same strongest

ORGAN DOSES AND EFFECTIVE DOSE FOR FIVE PET RADIOPHARMACEUTICALS

Diagnostic investigations with positron-emitting radiopharmaceuticals are dominated by (18)F-fluorodeoxyglucose ((18)F-FDG), but other radiopharmaceuticals are also commercially available or under development. Five of them, which are all clinically important, are (18)F-fluoride, (18)F-fluoroethyltyrosine ((18)F-FET), (18)F-deoxyfluorothymidine ((18)F-FLT), (18)F-fluorocholine ((18)F-choline) and (

Validity of a small low-cost triaxial accelerometer with integrated logger for uncomplicated measurements of postures and movements of head, upper back and upper arms

Repetitive work and work in constrained postures are risk factors for developing musculoskeletal disorders. Low-cost, user-friendly technical methods to quantify these risks are needed. The aims were to validate inclination angles and velocities of one model of the new generation of accelerometers with integrated data loggers against a previously validated one, and to compare meaurements when usin

A study of the influence of exhaust gas recirculation and stoichiometry on the heat release in the end-gas prior to knock using rotational coherent anti-Stokes-Raman spectroscopy thermometry

Heat release in the end-gas prior to autoignition was investigated using different experimental methods including transducers for heat flux and pressure as well as rotational coherent anti-Stokes-Raman spectroscopy, which is a laser-based method for non-intrusive instantaneous thermometry of the gas. The time history was examined in the cases of mixtures of various stoichio-metries, where some wer

Cereal Dietary Fibre - Physicochemical Properties and Suitability for Addition to Low-Fat Meat Products

Popular Abstract in Swedish Kostfiber kallas de kolhydrater från växtriket som inte bryts ner under matsmältningen och därför når tjocktarmen i stort sett opåverkade. Kostfiber finns till exempel i våra fyra sädesslag, havre, råg, korn och vete, vilka alla är cerealier. Framför allt är det de yttre delarna av cerealiekärnorna, klidelen, som innehåller mycket kostfiber. I cerealier är de vanligasteIt is well known that dietary fibre is good for the health. Cereals, and in particular the outer parts of the cereal kernels, are rich in dietary fibre. Rye bran, wheat bran, oat bran and barley fibre have been investigated regarding their suitability as additives in low-fat meat products. Two types of meat products, frankfurter-type sausages and meatballs have been evaluated in this thesis. In th

Development of Second and Third Generation Bioelectronics

The field of research dealing with the integration of biomolecules with electronic elements to form functional devices is called ‘‘bioelectronics’’. Bioelectronics based on mediated electron transfer (MET) between the biological element and the electrodes are designated as “second generation” while the one based on direct electron transfer (DET) is specified as “third generation”. Implanted bioele

Internal labour dynamics of a downsizing firm: The Swedish Tobacco Monopoly in the 1920s

Labour management in the past has been the studied by researchers from various disciplines and perspectives. Among labour economists and economic historians, there is an emerging current that aims to test hypotheses derived from theories about internal labour markets. So far, most studies have focused on companies whose workforces have been stable or expanding over time. This paper analyzes the in

Electrical isolation of coils in Soft Magnetic Composite applications

Soft Magnetic Composites (SMC) based on iron powder have a strong potential for improving both the performance and the manufacturing of various electromagnetic components and devices, such as inductors, induction heaters and electrical machines. A new casting or moulding method we have developed makes use of a modified composite, termed SM2C, or soft magnetic mouldable composite. Use of it makes i

The link between diffusion MRI and tumor heterogeneity : Mapping cell eccentricity and density by diffusional variance decomposition (DIVIDE)

The structural heterogeneity of tumor tissue can be probed by diffusion MRI (dMRI) in terms of the variance of apparent diffusivities within a voxel. However, the link between the diffusional variance and the tissue heterogeneity is not well-established. To investigate this link we test the hypothesis that diffusional variance, caused by microscopic anisotropy and isotropic heterogeneity, is assoc

Pedicle Screw Fixation Study in Immature Porcine Spines to Improve Pullout Resistance during Animal Testing

The porcine model is frequently used during development and validation of new spinal devices, because of its likeness to the human spine. These spinal devices are frequently composed of pedicle screws with a reputation for stable fixation but which can suffer pullouts during preclinical implantation on young animals, leading to high morbidity. With a view to identifying the best choices to optimiz

Determination of dust deposition and associated nutrients in natural forest and plantation - A case study from the moist semi-deciduous forest zone in Ghana

Every year in December to February the dust laden Harmattan blows from Sahara towards southwest to the countries along the east west going coast of the Gulf of Guinea. Only few investigations have quantified external dust deposition in forests and plantations in that region and hereby the nutrient input by dust. This paper investigates three different methods for sampling and quantifying dust depo

Inflation and switches between specie and paper standards in Sweden 1668-1931 : A public finance interpretation

In this study, the recent literature on the integration of fiscal and monetary policy is used to examine the suspensions and resumptions of currency convertibility in Sweden during the period 1668-1931. We demonstrate that urgent demands for financing of war expenditures forced the Swedish Riksbank to abandon convertibility of its notes in all cases of suspensions prior to 1914. We argue that the

Perceptions of diabetes control among people with type 2 diabetes treated with basal insulin in Sweden, Switzerland, and the United Kingdom

Objective: To investigate perceptions of control among people with uncontrolled and well controlled type 2 diabetes (T2D) treated with basal insulin, as well as differences in perceptions and diabetes management practices between the two groups. Research design and methods: Web surveys of 1012 people with uncontrolled T2D (HbA1c >8.0% or 64 mmol/mol) on basal insulin in Sweden, Switzerland, and th

Physical inactivity during leisure time and irregular meals are associated with functional gastrointestinal complaints in middle-aged and elder subjects

Objectives: Few studies have examined how lifestyle factors affect functional gastrointestinal disorders. The aim of this study was to see if leisure time physical inactivity, dietary habits or body mass index (BMI) were associated with increased risk of functional abdominal pain, functional bloating, functional constipation or functional diarrhea. Methods and materials: This study was based on a

Medborgarskapande på olika villkor : Självbilder, skolkoder och syn på kunskap i den svenska gymnasieskolan

Citizens are not born, they are made. Based on fieldwork in two upper-secondary school classes in Sweden – an Introductory Programme class and a Social Science Programme class – this dissertation focuses on how pupils form their identities as citizens in a democratic society. Citizens are made in interaction with the society they inhabit, an interaction where power is always present. Although Swed

The regional aerosol-climate model REMO-HAM

REMO-HAM is a new regional aerosol-climate model. It is based on the REMO regional climate model and includes most of the major aerosol processes. The structure for aerosol is similar to the global aerosol-climate model ECHAM5-HAM, for example the aerosol module HAM is coupled with a two-moment stratiform cloud scheme. On the other hand, REMO-HAM does not include an online coupled aerosol-radiatio

Sympathomimetic drug allergy: cross-reactivity study by patch test

INTRODUCTION: Sympathomimetic (alpha-adrenergic) drugs are mainly used because of their vasoconstrictor properties, for nasal congestion, or as mydriatics. Although sympathomimetic drugs are used often, allergic reactions are rare, especially when the drugs are administered systemically. Cross-reactivity may exist among catecholamine derivatives, although reported data on this are contradictory. I

Structural characterization of insulin NPH formulations

Insulin NPH (neutral protamine hagedorn) has for long been one of the most important therapeutic formulations for the treatment of diabetes. The protracted action profile of NPH formulations is gained from crystallizing insulin with zinc in the presence of the basic poly-arginine peptide protamine. In spite of its long history and successful use, the binding mode of the insulin-protamine complex i

Increased expression of non-muscle myosin heavy chain-B in connective tissue cells of hypertrophic rat urinary bladder

Expression of the non-muscle myosin heavy chain-B (NM-MHC-B, also denoted as the embryonic smooth muscle myosin heavy chain, SMemb) was examined in rat urinary bladder during growth in response to a partial urinary outflow obstruction. Following obstruction, the weight of the urinary bladder increased more than five-fold within 10 days. Immunohistochemistry with a polyclonal antiserum against the