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In the body, all cell surfaces are covered with glycans, and many regulatory components havecarbohydrates attached to them, which can aid in their function. Galectins are a family of proteins whichcan bind to specific glycans and oligosaccharides and cross-link them to influence a wide range of cellularprocesses. The members of the galectin family are structurally similar and can be involved in th
Background: Cardiovascular disease (CVD) is a major global health issue, primarily caused by atherosclerosis. Psychological factors may play a role in the development and progression of CVD. However, the relationship between psychological factors and atherosclerosis is complex and poorly understood. This study, therefore, aimed to examine the association of psychological factors with (i) coronary
While many industrial processes have been thoroughly exposed to machine learning models, the realm of powder metallurgy is still underexplored. This thesis aims to investigate the potential for a machine learning model to predict the characteristics of metal powders after a reduction annealing process using time series process data from the furnace. A supervised learning model was developed to pre
PURPOSE:Among available tumour necrosis factor inhibitors (TNF-inhibitors) only etanercept is approved for treatment of children with polyarticular course juvenile arthritis. Nevertheless also infliximab and adalimumab are used in selected cases, especially in patients having failed on etanercept.The objective was to evaluate adherence to therapy (a combined measure of efficacy and side effects as
Objective The aim of this work was to study the histologic and manometric changes in the distal esophagus beyond 2 years following endoscopic sclerotherapy (EST) and/or surgical intervention, and to try to understand the etiological factors associated with these changes. Patients and interventions Forty patients, with an average age of 61.5 years, were studied for 2-12 years following sclerotherap
OBJECTIVE: To identify predictors of sick leave and disability pension in patients with early rheumatoid arthritis (RA). METHODS: Individuals aged 19-59 years diagnosed with early RA (≤12 months symptom duration) were identified in the Swedish Rheumatology Quality Register (1999-2007; n=3029). We retrieved days of sick leave and disability pension from the Swedish Social Insurance Agency and basel
Purpose The purpose of this study was to examine psychometric properties of three translated versions of the Trust in Nurses Scale (TNS) and cancer patients’ perceptions of trust in nurses in a sample of cancer patients from four European countries. Methods A cross-sectional, cross-cultural, multi-site survey design was used. The data were collected with the Trust in Nurses Scale from patients wit
PURPOSE: We evaluated the biomechanical strength of two all suture anchors (ASA) of reduced diameter (1.4 mm) and compared them with the standard screw anchor (SA) with larger diameter (5.5 mm) used in rotator cuff tears. METHODS: We conducted 30 uniaxial vertical pullout tests using Material Testing System Instron 5566A until failure of the anchorage defined as rupture of the threads or anchor or
Progression from islet autoimmunity to clinical type 1 diabetes is influenced by genetic factors: results from the prospective TEDDY study 1Beyerlein A, et al. J Med Genet 2018;0:1–4. doi:10.1136/jmedgenet-2018-105532 Short report Progression from islet autoimmunity to clinical type 1 diabetes is influenced by genetic factors: results from the prospective TEDDY study Andreas Beyerlein,1 ezio Bonif
https://www.teddy.lu.se/sites/teddy.lu.se/files/2021-11/95%2010262018_679_95_MP165b_Beyerlein_JMedGenetics_2018.pdf - 2026-05-06
Abstract PTSD or Post Traumatic Stress Disorder (or, earlier, Syndrome) covers a great variety of symptoms which develop in a variety of contexts – accidents, natural disasters, terrorist attacks, wars and other events where people come face to face with violence and death. PTSD was included in the third edition of the Diagnostic and Statistical Manual of Mental Disorders, DSM-III, during the earl
Popular Abstract in Swedish I den här avhandlingen studeras de elektriska egenskaperna hos nanotrådar av halvledarmaterial. En halvledare är ett mellanting av en ledare och en isolator, där den elektriska ledningsförmågan kan styras både genom att förorena materialet med andra ämnen och genom att påverka materialet med ett elektriskt fält. I princip all modern elektronik bygger på komponenter av hThis thesis focuses on electron transport in semiconductor InAs/InP and InSb nanowire quantum devices. However, first the temperature dependence of classical charge transport in InSb nanowire field-effect transistors, FETs, is characterized, using InAs nanowire FETs as a reference. We find that the InSb FETs, in the same way as InAs FETs, are n-type with good current saturation and low voltage ope
Objective: To update estimates of cancer risk in SLE relative to the general population. Methods: A multisite international SLE cohort was linked with regional tumor registries. Standardized incidence ratios (SIRs) were calculated as the ratio of observed to expected cancers. Results: Across 30 centres, 16,409 patients were observed for 121,283 (average 7.4) person years. In total, 644 cancers occ
Background. Decompressive craniectomy (DC) is an option for the treatment of increased intracranial pressure resulting from an acute neurological insult, including insults caused by trauma. When the brain swelling has receded, the skull is reconstructed with a wide choice of materials, each with its own advantages and disadvantages in terms of cost, cosmetic appearance, biocompatibility, implant s
AIM: To examine whether rendezvous endoscopic retrograde cholangiopancreatography (ERCP) is associated with less pancreatic damage, measured as leakage of proenzymes, than conventional ERCP. METHODS: Patients (n = 122) with symptomatic gallstone disease, intact papilla and no ongoing inflammation, were prospectively enrolled in this case-control designed study. Eighty-one patients were subjected t
Whereas patients with multiple myeloma (MM) have a well-documented susceptibility to infections, this has been less studied in other B-cell disorders, such as Waldenstrom's macroglobulinemia (WM) and monoclonal gammopathy of undetermined significance (MGUS). We investigated the humoral immunity to 24 different pathogens in elderly patients with MM (n = 25), WM (n = 16), and MGUS (n = 18) and in ag
A systems approach was used to compare different heating systems from a consumer perspective. The whole energy system was considered from natural resources to the required energy services. District heating, electric heat pumps, electric boilers, natural-gas-, oil- or pellet-fired local boilers were considered when supplying heat to a detached house. The district heat production included wood-chip-
The paper is based on a joint research project between Lund University and Copenhagen Business School. The main research question is: Can the Oresund region position itself as a leading logistics centre in Scandinavia in light of the new conditions created by the bridge? The purpose is to create a fundamental understanding of the new logistics conditions in the Oresund region by identifying driver
This article is the second part of research on amylose-lipid complexes, where the first article dealt with monoglycerides. Here, a variety of fatty acids with chain lengths between 3 and 22 carbons and with varying degree of unsaturation were studied regarding their ability to form amylose-lipid complexes. In the present paper it is intended to investigate the formation of different fatty acid- am
