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Whole-genome Bisulfite Sequencing of Human Pancreatic Islets Reveals Novel Differentially Methylated Regions in Type 2 Diabetes Pathogenesis

Current knowledge about the role of epigenetics in type 2 diabetes (T2D) remains limited. Only a few studies have investigated DNA methylation of selected candidate genes or a very small fraction of genomic CpG sites in human pancreatic islets, the tissue of primary pathogenic importance for diabetes. Our aim was to characterize the whole-genome DNA methylation landscape in human pancreatic islets

Ultrasonographic fetal soft markers in a low-risk population : Prevalence, association with trisomies and invasive tests

Objective To investigate the prevalence of soft markers identified at second trimester ultrasound in a low-risk population and the association of these markers with trisomies and invasive testing. Design Prospective observational study. Setting Swedish University Hospital. Population All women with fetuses examined by ultrasound at 15+0-22+0 weeks gestation between July 2008 and March 2011. Method

Investigation of avian haemosporidian parasites from raptor birds in Turkey, with molecular characterisation and microscopic confirmation

Avian haemosporidians are common vector-borne blood parasites that have been reported in birds all over the world. Investigations of avian haemosporidian parasites are conducted mainly on passerine birds. However, studies that focus on non-passerine avian hosts are important for our understanding of the true diversity, host specificity and genetic variability among these widespread parasites. In t

Three New PAX2 Gene Mutations in Patients with Papillorenal Syndrome

Papillorenal syndrome (PAPRS; Mendelian Inheritance in Man [MIM] 120330) is an autosomal dominant disease characterised by the presence of congenital renal and optic nerve abnormalities associated with mutations of the PAX2 gene. In this article, the authors present four patients with PAPRS who are carriers of three new PAX2 mutations, as well as another patient with a possible non-pathogenic vari

Age of enlightenment : Long-term effects of outdoor aesthetic lights on bats in churches

We surveyed 110 country churches in south-western Sweden for presence of brown long-eared bats Plecotus auritus in summer 2016 by visual inspection and/or evening emergence counts. Each church was also classified according to the presence and amount of aesthetic directional lights (flood-lights) aimed on its walls and tower from the outside. Sixty-one of the churches had previously been surveyed b

Choral singing under the microscope : Identifying vocal leaders through comparison of individual recordings of the singers

Singing in groups and choirs is one of the main and generally most widespread musical activities: in schools at all levels among children and adolescents as well as in leisure time activities from "non-singer choirs" to more advanced and professional choirs. Previous studies indicate the need to identify vocal collaboration between choral singers. This article investigates how individuals in a cho

Significance of Ischemic Heart Disease in Patients with Heart Failure and Preserved, Midrange, and Reduced Ejection Fraction : A Nationwide Cohort Study

Background - The pathogenic role of ischemic heart disease (IHD) in heart failure (HF) with reduced ejection fraction (HFrEF; EF <40%) is well established, but its pathogenic and prognostic significance in HF with midrange (HFmrEF; EF 40%-50%) and preserved EF (HFpEF; EF ≥50%) has been much less explored. Methods and Results - We evaluated 42 987 patients from the Swedish Heart Failure Registry wi

Epidemiology of primary systemic vasculitis in children : a population-based study from southern Sweden

Objectives: To estimate the annual incidence rate of paediatric primary systemic vasculitis (PSV) in a defined geographical area in southern Sweden. Methods: Potential cases of PSV [IgA vasculitis (IgAV, Henoch–Schönlein purpura), Kawasaki disease (KD), granulomatosis with polyangiitis (GPA), microscopic polyangiitis (MPA), eosinophilic granulomatosis with polyangiitis (EGPA), polyarteritis nodosa

Modern Thermal Power Plants - Aspects on Modelling and Evaluation

The European Union (EU) has laid down very clear objectives for the reduction of greenhouse gases in the hope that it will prevent or mitigate climate change. Political incentives are used to make the power industry adopt changes in order to reach these EU targets. In this thesis, some solutions that could help power companies meet the EU objectives are evaluated. Thermodynamic models have been de

The different roles of crayfish in benthic food webs

Popular Abstract in Swedish Vad pysslar kräftorna med? Kräftor äter allt! Jag har visat att kräftor äter gamla blad från träd, alger, vattenväxter och även smådjur som till exempel sländlarver, iglar och sövattensgråsuggor. Dessa olika typer av mat har olika näringsvärde. Om vi jämför med vad vi äter så är det ju uppenbart att t.ex. västerbottenpaj och kokta kräftor har olika näringsvärde. Pajen I show that crayfish consume detritus, algae, macrophytes, and an array of invertebrates. Crayfish were found to reduce invertebrate densities. However, prey mobility seemed to be a key factor regulating the strength of interactions between crayfish and prey. Since crayfish seek to maximize growth, they benefit from feeding on invertebrates, shown to promote high growth rates. I found crayfish to

Mechanical Analysis of Lubrication and Lubricants

This thesis comprises three different topics within the field of tribology. First, design functions for analyses of slider bearings are developed. Second, a lubricant model applied to elastohydrodynamically lubricated (EHL) line contacts considering wall-slip is presented. Finally, an experimental apparatus for investigations of lubricants at high pressures is presented. The design of hydrodynami

Determination of age-specific and sex-specific familial risks for the different manifestations of venous thromboembolism: A nationwide family study in Sweden.

This nationwide study aimed to determine whether differences exist in age-specific and sex-specific familial risks for pulmonary embolism (PE), venous thrombosis of the lower limbs (VT) and other forms of venous thromboembolism (OVTE) among offspring, siblings and spouses of affected individuals. The Swedish Multi-Generation Register was linked to the Hospital Discharge Register data for the perio

Beslut-delegationsordning-20260212

FÖRSÄTTSSIDA STYRDOKUMENT Riktlinjer för fördelning av beslutsbefogenheter samt arbetsformer vid Samhällsvetenskapliga fakulteten Typ av styrdokument: Riktlinjer Definition av typen av styrdokument: Enligt universitetets riktlinjer för styrdokument (STYR 2024/1601) fastställer riktlinjer hur någon ska eller bör handla inom det område riktlinjerna omfattar. En ska-regel ska följas medan en bör-rege

https://www.sam.lu.se/internt/sites/sam.lu.se.internt/files/2026-02/beslut-delegationsordning-20260212.pdf - 2026-05-06

Juridiska-fakultetens-handlingsplan-for-forskning-och-utbildning-pa-forskarniva-221001--241231 0

Juridiska fakultetens handlingsplan för forskning och utbildning på forskarnivå 2022-2024 HANDLINGSPLAN 2022-09-21 Dnr STYR 2022/165 Juridiska fakultetsstyrelsen Juridiska fakultetens handlingsplan för forskning och utbildning på forskarnivå 2022-10-01–2024-12-31 Juridiska fakultetens strategiska plan omfattar perioden 2018–2026 och bygger på den strategiska planen för Lunds universitet för samma

https://www.jur.lu.se/sites/jur.lu.se/files/2026-01/Juridiska-fakultetens-handlingsplan-for-forskning-och-utbildning-pa-forskarniva-221001--241231_0.pdf - 2026-05-06

Schedule sgem20

SGEM20_2019_Course_programme – 1 – Human Geography SGEM20 GEOGRAPHICAL THOUGHT Autumn 2019 COURSE PROGRAMME SCHEDULE Day: Time: Room: Lecturer: Title: 2 Sep. 13:15 – 15 Rio HGL 1. Making geography (a) 4 Sep. 13:15 – 15 Rio HGL 2. Making geography (b) Regional geography (a) 6 Sep. 13:15 – 15 Rio HGL 3. Regional geography (b) (seminar) Spatial science (a) 9 Sep. 13:15 – 15 Rio HGL 4. Spatial science

https://www.keg.lu.se/en/sites/keg.lu.se.en/files/schedule_sgem20.pdf - 2026-05-06

Phd course invitation

Invitation to PhD course in: Methods in Causal Inferences for health economic and medical research (2 course credits) Lecture on May 9-10 and seminars on May 16 and June 4, 2019 Goal To give an overview and understanding of recent developments in methods for causal inference. To provide skills and experience in applying methods for causal inference in practical research. Content The course will gi

https://www.epihealth.lu.se/sites/epihealth.lu.se/files/phd_course_invitation.pdf - 2026-05-06

Wierup project 11

LUDC-IRC Postdoctoral Program 2020 – Project 11 LUDC-IRC Postdoctoral Program 2020 – Project 11 Incretin biology in T2D -Still a black box PI: Nils Wierup Co-PI: Marju Orho-Melander Purpose and aims Type 2 diabetes (T2D) is a major global health problem and there is a need for improved therapies. Here we will use unique approaches to identify T2D disease mechanisms by studies in the small intestin

https://www.ludc.lu.se/sites/ludc.lu.se/files/wierup_project_11.pdf - 2026-05-06

Rs-beslut-170127-170330

Bästa resultat får du om du öppnar den här PDF-portföljen i Acrobat X eller Adobe Reader X eller senare. Hämta Adobe Reader nu! http://www.adobe.com/go/reader_download_se Postadress Box 117, 221 00 Lund Besöksadress Universitetshuset, Paradisgatan 2 Telefon 046-222 70 24, 046-222 00 00, 072-231 71 64 E-post anna.akesson@rektor.lu.se Rektor Föreskrifter om val till universitetskollegiet samt val på

https://www.medarbetarwebben.lu.se/sites/medarbetarwebben.lu.se/files/rs-beslut-170127-170330.pdf - 2026-05-06

A2030 monthly Update 241209

Agenda 2030 Graduate School monthly newsletter #11 2024-12-09 Ylva van Meeningen Hi! Christmas preparations are in the air and it seems to be in a hurry this year. I think I am the last one on my street who have not set up my tree yet and everywhere you go there are lit up candy canes or little polar bears sitting around makeshift camp fires. There is even a house down the street who were not sati

https://www.agenda2030graduateschool.lu.se/sites/agenda2030graduateschool.lu.se/files/2025-02/A2030_monthly%20update_241209.pdf - 2026-05-06