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Pressure transduction and fluid evacuation during conventional negative pressure wound therapy of the open abdomen and NPWT using a protective disc over the intestines

Background: Negative pressure wound therapy (NPWT) has gained acceptance among surgeons, for the treatment of open abdomen, since very high closure rates have been reported with this method, compared to other kinds of wound management for the open abdomen. However, the method has occasionally been associated with increased development of fistulae. We have previously shown that NPWT induces ischemi

Pulsating flow and mass transfer in an asymmetric system of bifurcations

Pulsating flow through bifurcations are of general interest. In the human body such flows are also very common; for example in blood vessels and the respiratory tract. The characteristics of the flow in arteries have been related to the process of atherogenesis, based on the observation that the initial manifestation of the process is observed at certain common locations, i.e., near bifurcations i

Sexuality, apomixis and polyploidy; Potentilla argentea as a critical example

Popular Abstract in Swedish Denna avhandling utgår ifrån en önskan att finna en växtart som är diploid fakutativ apomikt. En diploid är en organism som, liksom människan, innehåller två kromosomuppsättningar, och en fakultativ apomikt är en växt som sätter frön både sexuellt (med befruktning) och apomiktiskt (utan befruktning). En växt med de begärda egenskaperna skulle ge oss goda möjligheter attFinding a diploid facultative apomictic plant species would give a great opportunity to solve problems concerning the existence and persistence of sexuality and also, it would be a possible source to get a transferable apomictic gene from. The putative diploid facultative apomict Potentilla argentea from southern Sweden was investigated with RAPD, isozymes and flow cytometry. Its mode of reproduct

Influence of hydrogen content on fracture toughness of CWSR Zr-2.5Nb pressure tube alloy

In this work, influence of hydrogen and temperature on the fracture toughness parameters of unirradiated, cold worked and stress relieved (CWSR) Zr-2.5Nb pressure tube alloys used in Indian Pressurized Heavy Water Reactor is reported. The fracture toughness tests were carried out using 17 mm width curved compact tension specimens machined from gaseously hydrogen charged tube-sections. Metallograph

Comparison of Four Single-Drug Regimens on Ventricular Rate and Arrhythmia-Related Symptoms in Patients With Permanent Atrial Fibrillation

Rate control of atrial fibrillation (AF) is a main treatment modality. However, data are scarce on the relative efficacy of calcium channel blockers and 13 blockers or between drugs within each class. The purpose of the present study was to compare the effect of 4 rate-reducing, once-daily drug regimens on the ventricular heart rate and arrhythmia-related symptoms in patients with permanent AF. We

Mechanisms of phagocytosis resistance in Streptococcus pyogenes

Popular Abstract in Swedish Streptococcus pyogenes (GAS) är en viktig sjukdomsframkallande bakterie som orsakar alltifrån lindriga infektioner som halsfluss (tonsillit) och svinkoppar (impetigo) till livshotande djupa infektioner som nekrotiserande fasceit eller ”Toxic shock syndrom”. På grund av det snabba sjukdomsförloppet i de livshotande infektionerna har streptokockerna fått beteckningen ”mörA distinguishing feature of Streptococcus pyogenes (GAS) is their ability to resist phagocytosis in whole human blood in the absence of type-specific antibodies, a property that is dependent on the expression of the surface associated M proteins. A common characteristic of M proteins is their interaction with a variety of host proteins including the complement regulatory protein factor H (FH) and

Novel Chromatography Matrices for Fast Isolation of Plasmid DNA

As new therapeutic areas in which genetic material is employed, i.e. gene therapy and DNA vaccination, are expanding, a substantial increase in the demand for gene vectors, e.g. plasmid DNA, is foreseen. Chromatography, being a high-resolution method, is considered essential for the purification of gene vectors when high purity is required. Plasmids are large molecules, which cannot penetrate the

Integrated optical read-out for polymeric cantilever-based sensors

Popular Abstract in Undetermined Denne afhandling præsenterer en ny udlæsnings metode udviklet til cantileverbaserede sensorer. Cantilevere er tynde vipper, der er fastgjorte i den ene ende, og som igennem de seneste ti °ar har vist sig at være en interessant ny type bio/kemisk sensor. Den specifikke genkendelse af et kemikalie viser sig ved at cantileveren bøjer som følge af det skabte overfladesThis thesis presents a novel read-out method developed for cantilever-based sensors. Cantilevers are thin beams clamped at one end and during the last 10 years they have emerged as an interesting new type of bio/chemical sensor. The specific recognition of a chemical manifests itself as a bending of the cantilever from the generated surface stress. Conventionally the read-out used for this type of

Elderly Immigrants, Socio-economic Status and Health. An epidemiological study of cardiovascular risk factors, impaired mobility and self-reported health status.

Popular Abstract in Swedish Under 1990-talet har vi bevittnat flera kriser i hela världen, men mest i Europa, Afrika och Mellanöstern. Det har oftast rört sig om inbördeskrig, men även om naturkatastrofer, fattigdom, samt politisk och/eller religiös förföljelse. Alla dessa faktorer har resulterat i en ökad migration. Enligt Statistiska centralbyrån (SCB) var 11,5 % av Sveriges befolkning utlandsfö

Exploring the Duration of EU Imports

The objective of this paper is twofold. First, against the background of an existing empirical literature on the duration of trade which has found that international trade is often of strikingly short duration, we aim to establish whether or not EU imports from the rest of the world also are short-lived. Second, since there is at this point no clear commonly accepted theoretical explanation for th

Factors influencing the skin exposure to diphenylguanidine in surgical gloves

Background: For health care personnelhandhygieneandwearing appropriate protective gloves are compulsory. We have noticed an increase of hand eczema caused by contact allergy from rubber chemicals such as diphenylguanidine (DPG) in synthetic rubber gloves used by surgeons and surgical nurses. The exposure time to surgical gloves as well as the number of gloves used per day vary. Furthermore surgery

Effects of tissue fixation and dehydration on tendon collagen nanostructure

Collagen is the most prominent protein in biological tissues. Tissue fixation is often required for preservation or sectioning of the tissue. This may affect collagen nanostructure and potentially provide incorrect information when analyzed after fixation. We aimed to unravel the effect of 1) ethanol and formalin fixation and 2) 24. h air-dehydration on the organization and structure of collagen f

Long-term variation in influenza A virus prevalence and subtype diversity in migratory mallards in northern Europe

Data on long-term circulation of pathogens in wildlife populations are seldom collected, and hence understanding of spatial-temporal variation in prevalence and genotypes is limited. Here, we analysed a long-term surveillance series on influenza A virus (IAV) in mallards collected at an important migratory stopover site from 2002 to 2010, and characterized seasonal dynamics in virus prevalence and

Comparing Self-Reported Sugar Intake With the Sucrose and Fructose Biomarker From Overnight Urine Samples in Relation to Cardiometabolic Risk Factors

Studies on sugar intake and its link to cardiometabolic risk show inconsistent results, partly due to dietary misreporting. Cost-effective and easily measured nutritional biomarkers that can complement dietary data are warranted. Measurement of 24-h urinary sugars is a biomarker of sugar intake, but there are knowledge gaps regarding the use of overnight urine samples. We aim to compare (1) overni

Angiotensin-Converting Enzyme Inhibitors and Angiotensin II Receptor Blockers Are Associated With Improved Outcome but do Not Prevent New-Onset Atrial Fibrillation After Acute Myocardial Infarction

Background-Treatment with renin-angiotensin system (RAS) inhibitors might restrain the structural/electrical remodeling associated with atrial fibrillation (AF). Limited evidence exists regarding the potential benefits of RAS inhibition post-acute myocardial infarction (AMI) in patients with AF. This study sought to assess the association between RAS inhibition and all-cause mortality and new-onse

Protease activation, pancreatic leakage, and inflammation in acute pancreatitis: differences between mild and severe cases and changes over the first three days.

BACKGROUND/AIMS: The pathophysiology of acute pancreatitis (AP) may be studied using markers of protease activation (active carboxypeptidase B (aCAP), the activation peptide of carboxypeptidase B (CAPAP)), leakage of pancreatic enzymes (trypsinogen-2, procarboxypeptidase B (proCAP), amylase), and inflammation (monocyte chemoattractant protein-1 (MCP-1), CRP). METHODS: This prospective study includ

Moisture Induced Stresses in Timber Structures

Wood is a hygroscopic material; always striving to reach equilibrium with the surrounding air, and consequently the moisture content is different in different climate conditions. The strength of wood is directly dependent on the moisture content, lower moisture content leads to increasing strength. Generally, state moisture equilibrium is seldom obtained because the moisture transport in wood is v