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Global sequence and dispersion of ventricular repolarization: In vivo validation of non-invasive parameters using monophasic action potential mapping technique

The purposes are to validate the noninvasive parameters, QT interval, QT dispersion, Tpeak-Tend interval, and the activation recovery time (ART) for estimation of global dispersion of ventricular repolarization (DVR), and to investigate the changes of repolarization sequence and DVR by altered ventricular pacing sites. The material consisted of 12 patients (Study I) and two series healthy pigs wi

Cytogenetic and fluorescence in situ hybridization characterization of chromosome 8 rearrangements in head and neck squamous cell carcinomas

Structural rearrangements of chromosome 8 are frequently encountered in squamous cell carcinomas of the head and neck (HNSCC). These aberrations often affect the centromeric region, resulting in the formation of isochromosome i(8q) and whole arm translocations. Some tumors may display structural rearrangements of 8p23. To characterize further the localization of the breakpoints in such rearrangeme

Size, concentration, and solvency effects on the viscosifying behavior of PEO-PS-PEO triblock copolymers in AOT oil-continuous microemulsions

The effect of changing the block lengths of triblock copolymers of poly(ethylene oxide) -polystyrene -poly(ethylene oxide) on the relative viscosity of AOT oil-continuous microemulsions, with cyclohexane as the oil, was investigated. Five different microemulsion compositions were used to have (a) a series of increasing droplet concentration at constant droplet size and (b) a series with increasing

Environmental Monitoring - using diode-laser-based spectroscopic techniques

Monitoring of environmental gases is necessary to understand the complex processes governing global warming and the impact of pollutant emissions related to human activity. Diode-laser-based spectroscopic techniques, being robust and affordable, have a great potential to become an industrially well-established technology for environmental sensing. This thesis deals with the further development of

Developments in radiotherapy

A systematic assessment of radiotherapy for cancer was conducted by The Swedish Council on Technology Assessment in Health Care (SBU) in 2001. The assessment included a review of future developments in radiotherapy and an estimate of the potential benefits of improved radiotherapy in Sweden. The conclusions reached from this review can be summarized as: Successively better knowledge is available o

Coagulation disturbances in the critically ill patient with special reference to prediction of outcome

Popular Abstract in Swedish Kritiskt sjuka patienter på intensivvårdsavdelningar (IVA) har ofta störningar i blodets levringsförmåga (koagulation). Kliniska tecken som blodpropp (djup ventrombos eller blodpropp i lungorna) och/eller blödning kan vara resultatet av aktivering och konsumtion av koagulationsfaktorer och koagulationshämmare. Disseminerad intravaskulär koagulation (DIC, som är en samtiCritically ill patients in intensive care units (ICU) often have coagulation disturbances. Clinical manifestations such as thromboembolism and/or bleeding may result from activation and consumption of coagulation factors and inhibitors. Disseminated intravascular coagulation (DIC) is a severe condition with an often-poor prognosis. Global haemostatic tests are inexpensive, widely available, and ma

Preoperative vestibular ablation with gentamicin and vestibular 'prehab' enhance postoperative recovery after surgery for pontine angle tumours - first report

Conclusions. Preoperative gentamicin in combination with vestibular 'prehab' offers a possibility to reduce postoperative malaise and speed up recovery and may be used for patients undergoing such surgery when there is remaining vestibular function. Objectives. Removal of pontine angle tumours in a patient with remaining vestibular function causes symptoms of acute vestibular loss. A simultaneous

Lund Stroke Register: hospitalization pattern and yield of different screening methods for first-ever stroke

Objectives To explore case ascertainment, hospitalization, characteristics of both hospitalized and non-hospitalized patients in a population-based group of stroke patients. Materials and methods One-year screening in Lund-Orup district for first-ever strokes using multiple prospective and retrospective methods. Results A total of 456 patients with first-ever stroke (n = 412 prospective screening

Large deletions of the PROS1 gene in a large fraction of mutationnegative patients with protein S deficiency

Protein S deficiency is an autosomal dominant disorder that results from mutations in the PROS I gene. Conventional mutation detection techniques fail to detect a pathogenic PROSI mutation in approximately 50% of cases. The present study investigates whether large deletions of PROS I are found in families where mutations in the PROS I gene have not been found despite sequencing. For this purpose,

Variation in sapflow and stem growth in relation to tree size, competition and thinning in a mixed forest of pine and spruce in Sweden

The aim of this study was to analyse the relationship between different biometric parameters and sapflow and growth, respectively, in order to assess their potential for use in scaling. The effect of thinning on these relationships was also investigated. The studied stand consisted of Scots pine (ca. 60%), Norway spruce (ca. 35%) and downy birch (ca. 5%). Sapflow was measured by the tissue heat-ba

Including everyone and boring no one : on the advantages and challenges of teaching interdisciplinary courses

For the 2012 Pedagogical Inspiration Conference for teachers at the Faculties of Humanities and Theology at Lund University, my course team and I presented a paper entitled “Interdisciplinarity, group responsibility and conflict as resources for learning”. The paper discussed our experiences with The City: Boundary Transgressions and Visual Expressions (KOVR02), an interdisciplinary course given i

Functional Data Analysis of Tongue Articulation in Palatal Vowels: Gothenburg and Malmöhus Swedish /i:, y:, u-:/

This study used Functional Data Analysis (FDA) to analyse tongue articulation dynamics, more specifically the height and frontness of the tongue body and tip in the palatal vowels /i:, y:, u-:/ of two varieties of Swedish. Articulatory data were collected from nine speakers each of Gothenburg and Malmöhus Swedish. Standard z-score transformations were used for speaker normalisation. Results showed

Functional data analysis of tongue articulation in Gothenburg and Malmöhus Swedish /i:, y:, u-:/

Articulatory data collected from nine speakers each of Gothenburg and Malmöhus Swedish were used in a Functional Data Analysis (FDA) to study tongue articulation dynamics, more specifically the height and frontness of the tongue body and tip in the palatal vowels /i ̆, y ̆, u̟ ̆/. Standard z-score transformations were used for speaker normalisation. Results showed that the tongue articulation for

Specific cysteine protease inhibitors act as deterrents of western flower thrips, Frankliniella occidentalis (Pergande), in transgenic potato

In this study, the effects of the accumulation of cysteine protease inhibitors on the food preferences of adult female western flower thrips, Frankliniella occidentalis (Pergande), were investigated. Representative members of the cystatin and thyropin gene families (stefin A, cystatin C, kininogen domain 3 and equistatin) were expressed in potato (Solanum tuberosum) cv. Impala, Kondor and Line V p

A description of some aspects of the triangular meeting between immigrant patients, their interpreters and GPs in primary health care in Stockholm, Sweden

Objectives. The first aim was to describe some aspects of each of the three perspectives in the triangular meeting between immigrant patients, interpreters and GPs, including their experiences, reflections and interactions during the consultation in primary health care. The second aim was to analyse patients' satisfaction with the consultation; whether satisfaction is influenced by respect for pat

Chronic hyperbaric exposure activates proinflammatory mediators in humans

Decompression illness (DCI) is an illness affecting divers subjected to reductions in ambient pressure. Besides a mechanical explanation to DCI, an inflammatory mechanism has been suggested. In this study, levels of interleukin (IL)-8, IL-6, IL-1 receptor antagonist (IL-1ra), secretory leukocyte protease inhibitor (SLPI), and neutrophil gelatinase-associated lipocalcin (NGAL) were measured in dive

Alterations in electroretinograms and retinal morphology in rabbits treated with vigabatrin

PURPOSE: To determine whether long-term treatment with the anti-epileptic drug vigabatrin causes damage to rabbit retina.METHODS: Five rabbits were treated continuously with a daily dose of vigabatrin solution per orally during a period of 1-8 months. Two rabbits receiving water were used as controls. Repeated full-field electroretinograms (every two weeks) were assessed during this period. Vigaba

Vision in the deep sea

The deep sea is the largest habitat on earth. Its three great faunal environments - the twilight mesopelagic zone, the dark bathypelagic zone and the vast flat expanses of the benthic habitat- are home to a rich fauna of vertebrates and invertebrates. In the mesopelagic zone (150-1000 in), the down-welling daylight creates an extended scene that becomes increasingly dimmer and bluer with depth. Th