Filetype
The protective effect of most currently available vaccines is dependent on high-affinity antibodies and long lived B cell memory, which develop within organized structures of secondary lymphoid organs called germinal centers (GCs). GC formation is supported by T follicular helper (Tfh) cells, a subset of CD4+ T cells that develop in parallel to other effector T cells and specifically localizes to
A mechanochemical method (grinding the components without added water - dry grinding, followed by further grinding in the presence of minute amount of water or NaOH solution - wet grinding) was used in this work for the preparation and intercalation of CaFe-layered double hydroxides (LDHs). Both the pristine LDHs and the amino acid anion (cystinate and tyrosinate) intercalated varieties were prepa
Alveolar rhabdomyosarcoma is an aggressive pediatric cancer of striated muscle characterized in 60% of cases by a t(2;13)(q35;q14). This results in the fusion of PAX3, a developmental transcription factor required for limb myogenesis, with FKHR, a member of the forkhead family of transcription factors. The resultant PAX3-FKHR gene possesses transforming properties; however, the effects of this chi
Antibody array-based technology is a powerful emerging tool in proteomics, but to enable global proteome analysis, antibody array layouts with even higher density has to be developed. To this end, we have further developed the first generation of a nanoarray platform, based on attoliter sized vials, attovials, which we have characterized and used for the detection of complement factor C1q in human
B cell superantigens (SAgs) have been implicated in human diseases by demonstrating non-clonotypic expansion of B cells bearing certain immunoglobulin variable region genes. One possibility is that, during infection with microorganisms secreting SAgs, these potent molecules might modulate BcR expression. To test this hypothesis, we investigated the potential effects of a SAg, protein L from Peptos
To determine which chemokine receptors might be involved in T lymphocyte localization to the intestinal mucosa, we examined receptor expression on human intestinal lamina propria lymphocytes (LPL), intraepithelial lymphocytes (IEL) and CD45RO+beta7hi gut homing peripheral blood lymphocytes (PBL). Virtually all LPL and IEL expressed CXCR3 and CCR5, receptors that have been associated with Th1(Tc1)/
In this chapter, we explore whether eyeblinks can be used as a measurementof spectators’ narrative transportation into a cinematic narrative. In ourexperiment, we show that spectators’ eyeblinks increase when watchingfilm clips together with what might be called congruent music. Increasedeyeblinks indicate an emotional arousal that motivates attention, whichin turn is a prerequisite for narrative
BACKGROUND AND OBJECTIVES: Polymorphic molecules expressed on the surface of certain blood cells are traditionally categorized as blood groups and human platelet or neutrophil antigens. CD36 is widely considered a platelet antigen (Nak a ) and anti-CD36 can cause foetal/neonatal alloimmune thrombocytopenia (FNAIT) in CD36-negative pregnant women. CD36 is used as a marker of differentiation in earl
Vision is often considered to top the hierarchy of the senses, reflected for example in the high relative frequency of vision verbs, in comparison to other perception verbs. Results from some previous studies, however, have shown that there is greater cross-linguistic variation concerning perception language than previously thought, emphasising other sense modalities than vision. This thesis condu
Making Europe climate neutral by 2050 is the primary goal of the European Green Deal. This goal has given rise to sustainable finance and action plans for financing sustainable growth. Such commitment is ensured by the legal initiatives put forward by the Commission. The Non-Financial Reporting Directive introduced the requirements for some firms to produce a sustainability report based on disclos
Lasers and masers have numerous uses in today’s society. Improving our understanding of the underlying physics and its application is thus of great importance. In this paper, the physics of a three-level maser when treated as a heat-engine was investigated: certain levels were coupled to thermal-reservoirs, effectively allowing for pumping without an external bias. The thermodynamical treatment fo
Syftet med denna studie är att undersöka vad som får elever att börja spela brassinstrument och vilka faktorer som motiverar dem till att fortsätta på Musik- och Kulturskolan. Bakgrunden till studien är att antalet elever på brassinstrumenten i Musik- och Kulturskolorna har minskat i Sverige under lång tid. Data består av gruppintervjuer med 11 elever i tre åldersbaserade grupper. Resultatet viThe purpose of this study is to investigate what motivates students to begin playing a brass instrument and the factors that motivate them to continue in the Community School of Music and Arts. The background for this study is that the number of students on brass instruments in the Community Schools of Music and Arts in Sweden has been decreasing for many years. Data collection was performed thro
This thesis explores current trends in social and political organising in Northern Syria, in areas controlled by the PYD. The research is built on discussions between eight participants from the Syrian Kurdish-speaking community living in the areas. While most discourses on Syria and the Kurdish-speaking community have a macro-political focus and produce racialising descriptions of “Kurdishness” i
This report is the result of a fire safety evaluation of the Royal Opera in Stockholm. This report was written as a project by students at the fire protection engineering program at Lund University. The objective of the evaluation is to ensure successful egress of visitors of the Royal Opera in case of fire. No concern has been taken of environmental or economical damage nor the safety of the staf
